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Total 15067 results found since Jan 2013.
Sulfur-aided aerobic biostabilization of swine manure and sawdust mixture: Humification and carbon loss
Bioresour Technol. 2023 Aug 1:129602. doi: 10.1016/j.biortech.2023.129602. Online ahead of print.ABSTRACTTo investigate how sulfur addition affects humification and carbon loss during swine manure (SM) biostabilisation, various proportions of sulfur, i.e., 0 (CK), 0.2%-0.8% (S1-S4) were added to SM in a 70-day pilot-scale test. Compared to CK (16.07%), sulfur addition resulted in the mineralization of 17.05%-24.27% of the total organic carbon. Sulfur addition also reduced CH4 emissions, which were 3.7%-29.3% lower than that of CK. The total global warming potential values were in the range of 913.1-968.2 g CO2 eq kg-1 for ...
Source: Bioresource Technology - August 3, 2023 Category: Biotechnology Authors: Yang Wang Jingwen Wang Guorong Yi Xuan Wu Xiu Zhang Xu Yang Kuok Ho Daniel Tang Ran Xiao Zengqiang Zhang Guangzhou Qu Ronghua Li Source Type: research
The effects of carbon nitrogen ratio and salinity on the treatment of swine digestion effluent simultaneously producing bioenergy by microalgae biofilm
Chemosphere. 2023 Aug 1;339:139694. doi: 10.1016/j.chemosphere.2023.139694. Online ahead of print.ABSTRACTIn order to remove high concentrations of ammonia nitrogen (NH4+-N) and refractory sulfamethazine (SM2) from swine digestion effluent, different carbon/nitrogen (C/N) ratios and salinity were used to determine the effects of pollutants removal in the microalgae biofilm system. Microalgae biofilm treatment under optimal environmental conditions in synthetic swine digestion effluent were C/N ratio of 20 and salinity of 140 mM. In order to make the actual swine digestion effluent discharge up to the standard, three differ...
Source: Chemosphere - August 3, 2023 Category: Chemistry Authors: Yiwen Mou Na Liu Tianxiang Lu Cong Jia Chongqing Xu Mingming Song Source Type: research
African Swine Fever Virus pF778R Attenuates Type I Interferon Response by Impeding STAT1 Nuclear Translocation
In this study, we discovered a negative regulation of the type I interferon (IFN) response by the ASFV ribonuclease reductase large subunit pF778R. This novel type Ⅰ IFN response antagonist significantly inhibits IFN-α-induced interferon-stimulated response element promoter activation, precludes the upregulation of various interferon-stimulated genes, and prevents STAT1 nuclear translocation. Mechanistically, pF778R did not affect the protein levels of crucial molecules in the JAK/STAT signaling pathway or engage in direct interactions. However, pF778R expression impedes type I IFN responses mediated by the JAK/STAT sig...
Source: Virus Research - August 3, 2023 Category: Virology Authors: Qichao Chen Liang Li Lixinjie Liu Zhankui Liu Shibang Guo Chen Tan Huanchun Chen Xiangru Wang Source Type: research
The role of zinc sulfate in enhancing cellular and humoral immune responses to foot-and-mouth disease vaccine
Virus Res. 2023 Aug 1:199189. doi: 10.1016/j.virusres.2023.199189. Online ahead of print.ABSTRACTFoot-and-mouth disease (FMD) is a rapidly propagating infectious disease of cloven-hoofed animals, especially cattle and pigs, affecting the productivity and profitability of the livestock industry. Presently, FMD is controlled and prevented using vaccines; however, conventional FMD vaccines have several disadvantages, including short vaccine efficacy, low antibody titers, and safety issues in pigs, indicating the need for further studies. Here, we evaluated the efficacy of a novel bivalent vaccine containing zinc sulfate as an...
Source: Virus Research - August 3, 2023 Category: Virology Authors: Mi-Kyeong Ko Hyeong Won Kim So Hui Park Jong-Hyeon Park Su-Mi Kim Min Ja Lee Source Type: research
The effects of carbon nitrogen ratio and salinity on the treatment of swine digestion effluent simultaneously producing bioenergy by microalgae biofilm
Chemosphere. 2023 Aug 1;339:139694. doi: 10.1016/j.chemosphere.2023.139694. Online ahead of print.ABSTRACTIn order to remove high concentrations of ammonia nitrogen (NH4+-N) and refractory sulfamethazine (SM2) from swine digestion effluent, different carbon/nitrogen (C/N) ratios and salinity were used to determine the effects of pollutants removal in the microalgae biofilm system. Microalgae biofilm treatment under optimal environmental conditions in synthetic swine digestion effluent were C/N ratio of 20 and salinity of 140 mM. In order to make the actual swine digestion effluent discharge up to the standard, three differ...
Source: Chemosphere - August 3, 2023 Category: Chemistry Authors: Yiwen Mou Na Liu Tianxiang Lu Cong Jia Chongqing Xu Mingming Song Source Type: research
Sulfur-aided aerobic biostabilization of swine manure and sawdust mixture: Humification and carbon loss
Bioresour Technol. 2023 Aug 1:129602. doi: 10.1016/j.biortech.2023.129602. Online ahead of print.ABSTRACTTo investigate how sulfur addition affects humification and carbon loss during swine manure (SM) biostabilisation, various proportions of sulfur, i.e., 0 (CK), 0.2%-0.8% (S1-S4) were added to SM in a 70-day pilot-scale test. Compared to CK (16.07%), sulfur addition resulted in the mineralization of 17.05%-24.27% of the total organic carbon. Sulfur addition also reduced CH4 emissions, which were 3.7%-29.3% lower than that of CK. The total global warming potential values were in the range of 913.1-968.2 g CO2 eq kg-1 for ...
Source: Bioresource Technology - August 3, 2023 Category: Biotechnology Authors: Yang Wang Jingwen Wang Guorong Yi Xuan Wu Xiu Zhang Xu Yang Kuok Ho Daniel Tang Ran Xiao Zengqiang Zhang Guangzhou Qu Ronghua Li Source Type: research
African Swine Fever Virus pF778R Attenuates Type I Interferon Response by Impeding STAT1 Nuclear Translocation
In this study, we discovered a negative regulation of the type I interferon (IFN) response by the ASFV ribonuclease reductase large subunit pF778R. This novel type Ⅰ IFN response antagonist significantly inhibits IFN-α-induced interferon-stimulated response element promoter activation, precludes the upregulation of various interferon-stimulated genes, and prevents STAT1 nuclear translocation. Mechanistically, pF778R did not affect the protein levels of crucial molecules in the JAK/STAT signaling pathway or engage in direct interactions. However, pF778R expression impedes type I IFN responses mediated by the JAK/STAT sig...
Source: Virus Research - August 3, 2023 Category: Virology Authors: Qichao Chen Liang Li Lixinjie Liu Zhankui Liu Shibang Guo Chen Tan Huanchun Chen Xiangru Wang Source Type: research
The role of zinc sulfate in enhancing cellular and humoral immune responses to foot-and-mouth disease vaccine
Virus Res. 2023 Aug 1:199189. doi: 10.1016/j.virusres.2023.199189. Online ahead of print.ABSTRACTFoot-and-mouth disease (FMD) is a rapidly propagating infectious disease of cloven-hoofed animals, especially cattle and pigs, affecting the productivity and profitability of the livestock industry. Presently, FMD is controlled and prevented using vaccines; however, conventional FMD vaccines have several disadvantages, including short vaccine efficacy, low antibody titers, and safety issues in pigs, indicating the need for further studies. Here, we evaluated the efficacy of a novel bivalent vaccine containing zinc sulfate as an...
Source: Virus Research - August 3, 2023 Category: Virology Authors: Mi-Kyeong Ko Hyeong Won Kim So Hui Park Jong-Hyeon Park Su-Mi Kim Min Ja Lee Source Type: research
Impaired cardiac glycolysis and glycogen depletion are linked to poor myocardial outcomes in juvenile male swine with metabolic syndrome and ischemia
This study reveals that MetS and ischemia diminishes ATP availability in the myocardium via altering t he glucose-G6P-pyruvate axis at the level of metabolites and gene expression of related enzymes. The observed severe glycogen depletion in MetS coincides with disbalance in expression of GYS1 and both PYGM and PYGL. This altered energy substrate metabolism is a potential target of pharmacological ag ents for improving juvenile myocardial function in MetS and ischemia.
Source: Physiological Reports - August 3, 2023 Category: Physiology Authors: Mark Broadwin,
Dwight D. Harris,
Sharif A. Sabe,
Elif Sengun,
Amber J. Sylvestre,
Boian S. Alexandrov,
Frank W. Sellke,
Anny Usheva Tags: ORIGINAL ARTICLE Source Type: research
An Experimental Cold Gas Cannon for the Study of Porcine Lung Contusion and Behind Armor Blunt Trauma
Ann Biomed Eng. 2023 Aug 2. doi: 10.1007/s10439-023-03334-7. Online ahead of print.ABSTRACTBehind armor blunt trauma (BABT) is a non-penetrating injury caused by the rapid deformation of body armor, by a projectile, which may in extreme circumstances cause death. The understanding of the mechanisms is still low, in relation to what is needed for safety threshold levels. Few models of graded kinetic energy transfer to the body exist. We established an experimental model for graded BABT. The cold gas cannon was air-driven, consisted of a pressure vessel, a barrel, and a pressure actuator. It required short training to operat...
Source: Annals of Biomedical Engineering - August 2, 2023 Category: Biomedical Engineering Authors: Tomas Karlsson Lars-Gunnar Olsson Jenny Gustavsson Ulf P Arborelius M årten Risling Mattias G ünther Source Type: research
Deciphering the immune reaction leading to spontaneous melanoma regression: initial role of MHCII+ CD163 − macrophages
AbstractThe human cutaneous metastatic melanoma is the deadliest skin cancer. Partial, or less frequently complete spontaneous regressions could be observed, mainly mediated by T cells. Nevertheless, the underlying mechanisms are not fully unraveled. We investigated the first events of the immune response related to cancer regression in Melanoma-bearing Libechov Minipigs (MeLiM), a unique swine model of cutaneous melanoma that regresses spontaneously. Using a multiparameter flow cytometry strategy and integrating new clinical and histological criteria of the regression, we show that T cells and B cells are present only in ...
Source: Cancer Immunology, Immunotherapy - August 1, 2023 Category: Cancer & Oncology Source Type: research
Long-term longitudinal study on swine VML model
Volumetric Muscle Loss (VML), resulting from severe trauma or surgical ablation, is a pathological condition preventing myofibers regeneration, since skeletal muscle owns the remarkable ability to restore tiss...
Source: Biology Direct - July 31, 2023 Category: Biology Authors: Francesca De Paolis, Stefano Testa, Gabriele Guarnaccia, Alessio Reggio, Ersilia Fornetti, Felice Cicciarelli, Rebecca Deodati, Sergio Bernardini, Daniele Peluso, Jacopo Baldi, Roberto Biagini, Flavia Cobianchi Bellisari, Antonio Izzo, Ferruccio Sgalambro Tags: Research Source Type: research
Viruses, Vol. 15, Pages 1667: Emergence and Prevalence of an African Swine Fever Virus Variant in Wild Boar Populations in South Korea from 2019 to 2022
Weon-Hwa Jheong
African swine fever (ASF), a viral disease caused by the African swine fever virus (ASFV), is associated with high mortality rates in domestic pigs and wild boars. ASF has been spreading since its discovery in wild boars in Korea in October 2019. Genomic analyses have provided insights into the genetic diversity of the ASFV isolated from various regions, enabling a better understanding of the virus origin and transmission patterns. We conducted a genome analysis to evaluate the diversity and mutations of ASFV spreading among wild boars in Korea during 2019–2022. We compared the genomes o...
Source: Viruses - July 31, 2023 Category: Virology Authors: Garam Kim So-Jeong Kim Won-Jun Kim Jung-Hyeuk Kim Ji-Chul Kim Sang-Geon Lee Eun-Sol Kim Sang-Hyun Lee Weon-Hwa Jheong Tags: Article Source Type: research
O-062 Novel endovascular technique for pharmacological block of superior cervical ganglion prevents sympathetic mediated cerebral vasospasm
ConclusionsWe demonstrate a novel endovascular technique of transmural delivery of lidocaine to the SCG and carotid artery perivascular tissues to inhibit sympathetic mediated cerebral vasospasm. These results suggest promising translation to humans for clinical use in patients suffering from cerebral vasospasm.Abstract O-062 Figure 1AP view of right neck showing positioning and transmural lidocaine injection using the Micro-Infusion Device. (A) Fluoroscopy single shot showing Micro-Infusion Device positioned in the right common carotid artery with needle aimed towards the SCG. Electric needle stimulators placed in the rig...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Kim, W., Samarage, H., Jaffari, M., Zarrin, D., Goel, K., Qi, X., Wang, A., Johnson, J., Colby, G. Tags: SNIS 20th annual meeting oral abstracts Source Type: research
