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Condition: Diabetes Mellitus
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Total 39189 results found since Jan 2013.
Implications of lifestyle changes on the incidence of childhood obesity - a systematic review and meta-analysis
CONCLUSIONS: An overall balanced diet, parental awareness pertaining to BMI and physical activity in children were the three major factors influencing a child's obesity levels. However, more studies are needed in this regard so as to ascertain a complete, holistic treatment plan that can further validate the implementation of our findings.PMID:37667948 | DOI:10.26355/eurrev_202308_33424
Source: European Review for Medical and Pharmacological Sciences - September 5, 2023 Category: Drugs & Pharmacology Authors: Y Abud Alanazi Source Type: research
Effect of sodium-glucose co-transporter-2 inhibitors on coronary blood flow in patients with type 2 diabetes mellitus
CONCLUSIONS: We have demonstrated that the use of SGLT-2is improves coronary artery blood flow in patients with T2DM who have normal or nearly normal coronary angiography.PMID:37667939 | DOI:10.26355/eurrev_202308_33414
Source: Pharmacological Reviews - September 5, 2023 Category: Drugs & Pharmacology Authors: E Ta ştan S S öner A D C ömert M Altunba ş R T üzün C Öztürk A Aky üz F I şık M Çap Ö Bilge M S üleymanoğlu M Ok şul Source Type: research
Placenta-derived exosomal miR-135a-5p promotes gestational diabetes mellitus pathogenesis by activating PI3K/AKT signalling pathway via SIRT1
In this study, we looked into how placental exosomes and their miRNAs may contribute to GDM. When compared to exosomes from healthy pregnant women, it was discovered that miR-135a-5p was elevated in placenta-derived exosomes that were isolated from the maternal peripheral plasma of GDM women. Additionally, we discovered that miR-135a-5p encouraged HTR-8/SVneo cell growth, invasion and migration. Further research revealed that miR-135a-5p activates HTR-8/SVneo cells' proliferation, invasion and migration by promoting PI3K/AKT pathway activity via Sirtuin 1 (SIRT1). The transfer of exosomal miR-135a-5p generated from the pla...
Source: J Cell Mol Med - September 5, 2023 Category: Molecular Biology Authors: Qiuyu Zhang Xu Ye Xia Xu Jianying Yan Source Type: research
A randomized placebo-controlled, double-blind study to investigate the effect of a high oral loading dose of cholecalciferol in non-alcoholic fatty liver disease patients, new insights on serum STAT-3 and hepassocin
CONCLUSIONS: Cholecalciferol is recommended as additional therapy to modulate lipid peroxidation and systemic inflammation alongside other NAFLD therapies.PMID:37667938 | DOI:10.26355/eurrev_202308_33413
Source: Pharmacological Reviews - September 5, 2023 Category: Drugs & Pharmacology Authors: S J Alarfaj M M Bahaa H A Yassin E El-Khateeb F A Kotkata M A El-Gammal A I Elberri E Habba E E Zien El-Deen M O Khrieba T A El-Masry W A Negm E I Elberri Source Type: research
Association between serum asprosin and diabetic peripheral neuropathy in patients with type 2 diabetes mellitus in the community
CONCLUSIONS: Serum asprosin was found to be positively correlated with DPN, and it resulted as an influencing factor for DPN in patients with T2DM in the community. With the increase of asprosin, the risk of DPN also increased.PMID:37667933 | DOI:10.26355/eurrev_202308_33408
Source: Pharmacological Reviews - September 5, 2023 Category: Drugs & Pharmacology Authors: L-X Xu J-H Yin D Liang P Li M-G Xu G-L Shi Y Wang J Yang Source Type: research
Diabetes and factors associated with cognitive and functional decline. The screening for CKD among older people across Europe (SCOPE) study
CONCLUSION: Decline in functional and cognitive status of community-dwelling older adults with DM was similar to participants without DM in a short period of 2 years of follow-up, though several clinical factors may increase its risk in this population.PMID:37668841 | DOI:10.1007/s40520-023-02536-2
Source: Aging Clinical and Experimental Research - September 5, 2023 Category: Geriatrics Authors: Francesc Formiga Ana Mar ía Badía-Tejero Andrea Corsonello Johan Ärnlöv Axel C Carlsson Francesco Mattace-Raso Lisanne Tap Tomasz Kostka Agnieszka Guligowska Cornel C Sieber Robert Kob Ronit Ben-Romano Ilan Yehoshua Regina Roller-Wirnsberger Gerhard H Source Type: research
Implications of lifestyle changes on the incidence of childhood obesity - a systematic review and meta-analysis
CONCLUSIONS: An overall balanced diet, parental awareness pertaining to BMI and physical activity in children were the three major factors influencing a child's obesity levels. However, more studies are needed in this regard so as to ascertain a complete, holistic treatment plan that can further validate the implementation of our findings.PMID:37667948 | DOI:10.26355/eurrev_202308_33424
Source: Pharmacological Reviews - September 5, 2023 Category: Drugs & Pharmacology Authors: Y Abud Alanazi Source Type: research
Predictive performance of CHA2DS2-VASc-HS score and Framingham risk scores for coronary disease severity in ischemic heart disease patients with invasive coronary angiography
CONCLUSIONS: Our study demonstrated a high predictive performance of coronary artery injury using the CHA2DS2-VASc-HS score and Framingham risk scores. These scores could be applied in predicting ischemic heart disease in non-symptomatic cases where invasive coronary angiography is not indicated.GRAPHICAL ABSTRACT: https://www.europeanreview.org/wp/wp-content/uploads/Graphical-abstract-4.jpg.PMID:37667940 | DOI:10.26355/eurrev_202308_33415
Source: Pharmacological Reviews - September 5, 2023 Category: Drugs & Pharmacology Authors: A-V Tran K-D Nguyen K-D Nguyen A-T Huynh B-L-T Tran T-H Ngo Source Type: research
Effect of sodium-glucose co-transporter-2 inhibitors on coronary blood flow in patients with type 2 diabetes mellitus
CONCLUSIONS: We have demonstrated that the use of SGLT-2is improves coronary artery blood flow in patients with T2DM who have normal or nearly normal coronary angiography.PMID:37667939 | DOI:10.26355/eurrev_202308_33414
Source: Pharmacological Reviews - September 5, 2023 Category: Drugs & Pharmacology Authors: E Ta ştan S S öner A D C ömert M Altunba ş R T üzün C Öztürk A Aky üz F I şık M Çap Ö Bilge M S üleymanoğlu M Ok şul Source Type: research
A randomized placebo-controlled, double-blind study to investigate the effect of a high oral loading dose of cholecalciferol in non-alcoholic fatty liver disease patients, new insights on serum STAT-3 and hepassocin
CONCLUSIONS: Cholecalciferol is recommended as additional therapy to modulate lipid peroxidation and systemic inflammation alongside other NAFLD therapies.PMID:37667938 | DOI:10.26355/eurrev_202308_33413
Source: Pharmacological Reviews - September 5, 2023 Category: Drugs & Pharmacology Authors: S J Alarfaj M M Bahaa H A Yassin E El-Khateeb F A Kotkata M A El-Gammal A I Elberri E Habba E E Zien El-Deen M O Khrieba T A El-Masry W A Negm E I Elberri Source Type: research
Association between serum asprosin and diabetic peripheral neuropathy in patients with type 2 diabetes mellitus in the community
CONCLUSIONS: Serum asprosin was found to be positively correlated with DPN, and it resulted as an influencing factor for DPN in patients with T2DM in the community. With the increase of asprosin, the risk of DPN also increased.PMID:37667933 | DOI:10.26355/eurrev_202308_33408
Source: Pharmacological Reviews - September 5, 2023 Category: Drugs & Pharmacology Authors: L-X Xu J-H Yin D Liang P Li M-G Xu G-L Shi Y Wang J Yang Source Type: research
Placenta-derived exosomal miR-135a-5p promotes gestational diabetes mellitus pathogenesis by activating PI3K/AKT signalling pathway via SIRT1
In this study, we looked into how placental exosomes and their miRNAs may contribute to GDM. When compared to exosomes from healthy pregnant women, it was discovered that miR-135a-5p was elevated in placenta-derived exosomes that were isolated from the maternal peripheral plasma of GDM women. Additionally, we discovered that miR-135a-5p encouraged HTR-8/SVneo cell growth, invasion and migration. Further research revealed that miR-135a-5p activates HTR-8/SVneo cells' proliferation, invasion and migration by promoting PI3K/AKT pathway activity via Sirtuin 1 (SIRT1). The transfer of exosomal miR-135a-5p generated from the pla...
Source: J Cell Mol Med - September 5, 2023 Category: Molecular Biology Authors: Qiuyu Zhang Xu Ye Xia Xu Jianying Yan Source Type: research
Diabetes and factors associated with cognitive and functional decline. The screening for CKD among older people across Europe (SCOPE) study
CONCLUSION: Decline in functional and cognitive status of community-dwelling older adults with DM was similar to participants without DM in a short period of 2 years of follow-up, though several clinical factors may increase its risk in this population.PMID:37668841 | DOI:10.1007/s40520-023-02536-2
Source: Aging Clinical and Experimental Research - September 5, 2023 Category: Geriatrics Authors: Francesc Formiga Ana Mar ía Badía-Tejero Andrea Corsonello Johan Ärnlöv Axel C Carlsson Francesco Mattace-Raso Lisanne Tap Tomasz Kostka Agnieszka Guligowska Cornel C Sieber Robert Kob Ronit Ben-Romano Ilan Yehoshua Regina Roller-Wirnsberger Gerhard H Source Type: research
