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Condition: Diabetes Mellitus
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Total 39189 results found since Jan 2013.
The Intersocietal IWGDF, ESVS, SVS Guidelines on Peripheral Artery Disease in People With Diabetes Mellitus and a Foot Ulcer
Eur J Vasc Endovasc Surg. 2023 Sep 6:S1078-5884(23)00586-5. doi: 10.1016/j.ejvs.2023.07.020. Online ahead of print.ABSTRACTDiabetes related foot complications have become a major cause of morbidity and are implicated in most major and minor amputations globally. Approximately 50% of people with diabetes and a foot ulcer have peripheral artery disease (PAD) and the presence of PAD significantly increases the risk of adverse limb and cardiovascular events. The International Working Group on the Diabetic Foot (IWGDF) has published evidence based guidelines on the management and prevention of diabetes related foot complication...
Source: PubMed: Eur J Vasc Endovasc ... - September 19, 2023 Category: Surgery Authors: Robert Fitridge Vivienne Chuter Joseph Mills Robert Hinchliffe Nobuyoshi Azuma Christian-Alexander Behrendt Edward J Boyko Michael S Conte Misty Humphries Lee Kirksey Katharine C McGinigle Sigrid Nikol Joakim Nordanstig Vincent Rowe David Russell Jos C va Source Type: research
Control of diabetes mellitus and the risk of neointimal hyperplasia after percutaneous coronary intervention: Post-hoc analysis from the BLADE-PCI trial
CONCLUSIONS: Uncontrolled DM at the time of PCI performed with contemporary drug-eluting stents was not associated with an increased risk of NIH development.PMID:37726192 | DOI:10.1016/j.atherosclerosis.2023.117264
Source: Atherosclerosis - September 19, 2023 Category: Cardiology Authors: Michael Jonas Philippe Genereux Akiko Maehara Ori Ben-Yehuda Gregg W Stone Gil Chernin Source Type: research
Maintaining renin-angiotensin-aldosterone system inhibitor treatment with patiromer in hyperkalaemic chronic kidney disease patients: comparison of a propensity-matched real-world population with AMETHYST-DN
CONCLUSIONS: These results demonstrate the benefit of patiromer for sK+ management to enable RAASi use, while revealing beneficial effects on BP.PMID:37725919 | DOI:10.1159/000533753
Source: American Journal of Nephrology - September 19, 2023 Category: Urology & Nephrology Authors: Rajkumar Chinnadurai Sharmilee Rengarajan Jeffrey J Budden Carol Moreno Quinn Philip A Kalra Source Type: research
Error traps in the perioperative management of children with type 1 diabetes
This article reviews common errors of associated with the perioperative management of patients with T1D, including failure to assess and coordinate patient care preoperatively; failure to understand diabetes management and technology; failure to monitor blood glucose and recognize dysglycemia; and failure to appropriately administer basal insulin.PMID:37724489 | DOI:10.1111/pan.14763
Source: Paediatric Anaesthesia - September 19, 2023 Category: Anesthesiology Authors: M Hoagland B Duggar J Hamrick G Todd Alonso L Martin Source Type: research
Finerenone (Kerendia) for the Treatment of Chronic Kidney Disease in Patients With Type 2 Diabetes Mellitus
Am Fam Physician. 2023 Sep;108(3):305-306.NO ABSTRACTPMID:37725467
Source: American Family Physician - September 19, 2023 Category: Primary Care Authors: Autumn Stewart-Lynch Source Type: research
Gestational Diabetes Mellitus: Update on Screening, Diagnosis, and Management
Am Fam Physician. 2023 Sep;108(3):249-258.ABSTRACTGestational diabetes mellitus (GDM) is a common condition of pregnancy with increasing prevalence in the United States. GDM increases risks of complications, including operative delivery, hypertensive disorders, shoulder dystocia, fetal macrosomia, large-for-gestational-age infants, neonatal hypoglycemia, and neonatal respiratory distress. In patients who are overweight or obese, prepregnancy weight loss and lifestyle modifications during pregnancy may prevent GDM. First-trimester screening can identify preexisting diabetes and early-onset GDM for prompt implementation of g...
Source: American Family Physician - September 19, 2023 Category: Primary Care Authors: Joshua S Will Holly Crellin Source Type: research
Diverticulosis and cardiometabolic risk factors: a systematic literature review
ConclusionBased on the synthesized data, there is an association between arterial hypertension, obesity, and fatty liver disease in younger patients. The formation of diverticula seems to be influenced by age and genetic factors. The study suggests a connection with cardiometabolic risk factors. To gain a better understanding of the role of metabolic risk factors in asymptomatic diverticulosis, targeted studies are necessary based on these findings.
Source: International Journal of Colorectal Disease - September 19, 2023 Category: Gastroenterology Source Type: research
Identification of quality markers for < em > Cyanotis arachnoidea < /em > and analysis of its physiological mechanism based on chemical pattern recognition, network pharmacology, and experimental validation
In this study, ultra-high-performance liquid chromatography (UHPLC) fingerprint combined with chemical pattern recognition were performed, and four differential components were screened out as quality markers, including 20-Hydroxyecdysone, 3-O-acetyl-20-hydroxyecdysone, Ajugasterone C, and 2-O-acetyl-20-hydroxyecdysone. Network pharmacology analysis revealed 107 therapeutic target genes of Cyanotis arachnoidea in DM treatment, and the key targets were Akt1, TNF, IL-6, MAPK3, and JUN. The hypoglycemic mode of action of Cyanotis arachnoidea may be mediated by tumor necrosis factor (TNF) signaling, cancer, insulin resistance,...
Source: Cancer Control - September 18, 2023 Category: Cancer & Oncology Authors: Jingnan Hu Yu Feng Baolin Li Fengxia Wang Qi Qian Wei Tian Liying Niu Xinguo Wang Source Type: research
Health profile of workers from different industries in Singapore
CONCLUSION: Health issues are prevalent in the workforce and may affect work and employee safety. It is increasingly important for employees' health to be considered in risk assessments and prioritised in workplace safety and health management systems and strategies. Health promotion interventions should be targeted, and multilevel and multicomponent initiatives should be integrated with pre-existing occupational safety programmes.PMID:37721304 | DOI:10.4103/singaporemedj.SMJ-2021-414
Source: Singapore Medical Journal - September 18, 2023 Category: General Medicine Authors: Sin Eng Chia Mei Ling Tan Elise Cheok Peh Woon Ong Source Type: research
Monoamines' role in islet cell function and type 2 diabetes risk
Trends Mol Med. 2023 Sep 16:S1471-4914(23)00194-6. doi: 10.1016/j.molmed.2023.08.009. Online ahead of print.ABSTRACTThe two monoamines serotonin and melatonin have recently been highlighted as potent regulators of islet hormone secretion and overall glucose homeostasis in the body. In fact, dysregulated signaling of both amines are implicated in β-cell dysfunction and development of type 2 diabetes mellitus (T2DM). Serotonin is a key player in β-cell physiology and plays a role in expansion of β-cell mass. Melatonin regulates circadian rhythm and nutrient metabolism and reduces insulin release in human and rodent islets...
Source: Molecular Medicine - September 18, 2023 Category: Molecular Biology Authors: Fiona Louise Roberts Luis Rodrigo Cataldo Malin Fex Source Type: research
Clinical and Epidemiological Profile of Herpes Zoster and Its Complications in a Tertiary Care Center of Bihar: A Prospective Study
Conclusion A broader understanding of the clinical and epidemiological factors of herpes zoster and post-herpetic complications is important as this disease constitutes a considerable burden in a tertiary care center and if not treated adequately, the after-effects might last for many years altogether. Hence, early diagnosis and initiation of adequate antiviral therapy as well as pain management is the key aspect of management.PMID:37719532 | PMC:PMC10503883 | DOI:10.7759/cureus.43560
Source: Herpes - September 18, 2023 Category: Infectious Diseases Authors: Rajesh Sinha Pinki Kumari U K Pallavi Subhasree Sarkar Source Type: research
Resveratrol ameliorates diabetic encephalopathy through PDE4D/PKA/Drp1 signaling
This study illustrated the role of PDE4D in DE and investigated whether resveratrol protected against DE via inhibiting PDE4D. db/db male mice and hippocampus cell line (HT22) were used to investigate the role of PDE4D and the protective effect of resveratrol on cognitive function under high glucose (HG). PDE4D overexpression or knockdown lentivirus and PKA specific inhibitor H89 were used to further identify the indispensable role of PDE4D/PKA signaling pathway in resveratrol's amelioration effect of neurotoxicity. Resveratrol attenuated cognitive impairment in db/db mice, reduced PDE4D protein, restored the impaired mito...
Source: Brain Research Bulletin - September 18, 2023 Category: Neurology Authors: Yanjuan Cao Wen Sun Chang Liu Zihui Zhou Zongli Deng Mingjie Zhang Meng Yan Xiaoxing Yin Xia Zhu Source Type: research
Molecular docking analysis of calcium channel blockers with ALR2 and RAGE
We report that 1, 4-dihydropyridine compounds, particularly Benidipine, bind to the active sites with good efficiency. Thus, 1,4 dihydropyridine derivatives can be considered for further confirmation in drug discovery.PMID:37720280 | PMC:PMC10504517 | DOI:10.6026/97320630019028
Source: Bioinformation - September 18, 2023 Category: Bioinformatics Authors: Samreen Kazmi Surekha Challa Malini Devi Alaparthi Indira Devi M Swetha Sudha Nagamalla Priya Ej Source Type: research
