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Sarcopenic obesity and hypertension in elderly patients: a narrative review of pathophysiology and management strategies
CONCLUSION: Sarcopenic obesity and hypertension present significant challenges to global public health. Addressing arterial stiffness is paramount in managing these conditions effectively. Lifestyle modifications, including weight management and physical activity, remain central to the treatment of sarcopenic obesity, while additional research is needed to explore potential pharmacological options.PMID:37712242 | DOI:10.4415/ANN_23_03_10
Source: Annali dell'Istituto Superiore di Sanita - September 15, 2023 Category: International Medicine & Public Health Authors: Mihaela Jurdana Lovro Žiberna Source Type: research

Report on Cardiovascular Health and Diseases in China 2022: an Updated Summary
Biomed Environ Sci. 2023 Aug 20;36(8):669-701. doi: 10.3967/bes2023.106.ABSTRACTIn the past 30 years, the accessibility and quality index of medical care have made remarkable progress in China, ranking the first among middle-income countries. Many cardiovascular technologies are at or near the world's leading level, and significant progress has been achieved in China solving the problem of "treatment difficulty" of cardiovascular diseases (CVD). However, due to the prevalence of unhealthy lifestyles among Chinese residents, a huge population with CVD risk factors, accelerated population aging, and other reasons, the incide...
Source: Biomedical and Environmental Sciences : BES - September 15, 2023 Category: Biomedical Science Authors: Writing Committee Of The Report On Cardiovascular Health And Diseases In China The Source Type: research

Mitochondria Derived Vesicle Packaging as a Novel Therapeutic Mechanism in Pulmonary Hypertension
Am J Respir Cell Mol Biol. 2023 Sep 15. doi: 10.1165/rcmb.2023-0010OC. Online ahead of print.ABSTRACTIncreasing evidence suggests that mitochondrial dysfunction in pulmonary endothelial cells (ECs) plays a causative role in the initiation and progression of pulmonary hypertension (PH); how mitochondria become dysfunctional in PH remains elusive. Mitochondria-derived vesicles (MDVs) are small subcellular vesicles that excise from mitochondria. Whether or not MDVs deregulation causes mitochondrial dysfunction in PH is unknown. This aim of this study was to determine MDVs regulation in ECs and to elucidate how MDVs deregulati...
Source: Am J Respir Cell Mol... - September 15, 2023 Category: Respiratory Medicine Authors: Qiang Zhao Zhixue Liu Ping Song Zuyi Yuan Ming-Hui Zou Source Type: research

Tissue Transglutaminase: A Multifunctional and Multisite Regulator in Health and Disease
In conclusion, TG2 provides a multifunctional and multisite response to physiological stress.PMID:37712623 | DOI:10.1152/physrev.00003.2023
Source: Physiological Reviews - September 15, 2023 Category: Physiology Authors: Zhouzhou Yao Yuhua Fan Lizhen Lin Rodney E Kellems Yang Xia Source Type: research

Report on Cardiovascular Health and Diseases in China 2022: an Updated Summary
Biomed Environ Sci. 2023 Aug 20;36(8):669-701. doi: 10.3967/bes2023.106.ABSTRACTIn the past 30 years, the accessibility and quality index of medical care have made remarkable progress in China, ranking the first among middle-income countries. Many cardiovascular technologies are at or near the world's leading level, and significant progress has been achieved in China solving the problem of "treatment difficulty" of cardiovascular diseases (CVD). However, due to the prevalence of unhealthy lifestyles among Chinese residents, a huge population with CVD risk factors, accelerated population aging, and other reasons, the incide...
Source: Biomedical and Environmental Sciences : BES - September 15, 2023 Category: Biomedical Science Authors: Writing Committee Of The Report On Cardiovascular Health And Diseases In China The Source Type: research

Tissue Transglutaminase: A Multifunctional and Multisite Regulator in Health and Disease
In conclusion, TG2 provides a multifunctional and multisite response to physiological stress.PMID:37712623 | DOI:10.1152/physrev.00003.2023
Source: Physiological Reviews - September 15, 2023 Category: Physiology Authors: Zhouzhou Yao Yuhua Fan Lizhen Lin Rodney E Kellems Yang Xia Source Type: research

Sarcopenic obesity and hypertension in elderly patients: a narrative review of pathophysiology and management strategies
CONCLUSION: Sarcopenic obesity and hypertension present significant challenges to global public health. Addressing arterial stiffness is paramount in managing these conditions effectively. Lifestyle modifications, including weight management and physical activity, remain central to the treatment of sarcopenic obesity, while additional research is needed to explore potential pharmacological options.PMID:37712242 | DOI:10.4415/ANN_23_03_10
Source: Ann Ist Super Sanita - September 15, 2023 Category: Biomedical Science Authors: Mihaela Jurdana Lovro Žiberna Source Type: research

Report on Cardiovascular Health and Diseases in China 2022: an Updated Summary
Biomed Environ Sci. 2023 Aug 20;36(8):669-701. doi: 10.3967/bes2023.106.ABSTRACTIn the past 30 years, the accessibility and quality index of medical care have made remarkable progress in China, ranking the first among middle-income countries. Many cardiovascular technologies are at or near the world's leading level, and significant progress has been achieved in China solving the problem of "treatment difficulty" of cardiovascular diseases (CVD). However, due to the prevalence of unhealthy lifestyles among Chinese residents, a huge population with CVD risk factors, accelerated population aging, and other reasons, the incide...
Source: Biomedical and Environmental Sciences : BES - September 15, 2023 Category: Biomedical Science Authors: Writing Committee Of The Report On Cardiovascular Health And Diseases In China The Source Type: research

Characteristics and Predictors of Apparent Treatment Resistant Hypertension in Real-World Populations Using Electronic Health Record-Based Data
CONCLUSIONS: In two large, diverse real-world populations, we observed similar comorbidities and predictors of aTRH as prior studies. In the future, these results may be used to improve healthcare professionals' understanding of aTRH predictors and associated comorbidities.PMID:37712350 | DOI:10.1093/ajh/hpad084
Source: American Journal of Hypertension - September 15, 2023 Category: Cardiology Authors: Eissa Jafari Rhonda M Cooper-DeHoff Mark B Effron William R Hogan Caitrin W McDonough Source Type: research

Mitochondria Derived Vesicle Packaging as a Novel Therapeutic Mechanism in Pulmonary Hypertension
Am J Respir Cell Mol Biol. 2023 Sep 15. doi: 10.1165/rcmb.2023-0010OC. Online ahead of print.ABSTRACTIncreasing evidence suggests that mitochondrial dysfunction in pulmonary endothelial cells (ECs) plays a causative role in the initiation and progression of pulmonary hypertension (PH); how mitochondria become dysfunctional in PH remains elusive. Mitochondria-derived vesicles (MDVs) are small subcellular vesicles that excise from mitochondria. Whether or not MDVs deregulation causes mitochondrial dysfunction in PH is unknown. This aim of this study was to determine MDVs regulation in ECs and to elucidate how MDVs deregulati...
Source: American Journal of Respiratory Cell and Molecular Biology - September 15, 2023 Category: Molecular Biology Authors: Qiang Zhao Zhixue Liu Ping Song Zuyi Yuan Ming-Hui Zou Source Type: research

Tissue Transglutaminase: A Multifunctional and Multisite Regulator in Health and Disease
In conclusion, TG2 provides a multifunctional and multisite response to physiological stress.PMID:37712623 | DOI:10.1152/physrev.00003.2023
Source: Physiological Reviews - September 15, 2023 Category: Physiology Authors: Zhouzhou Yao Yuhua Fan Lizhen Lin Rodney E Kellems Yang Xia Source Type: research

Sarcopenic obesity and hypertension in elderly patients: a narrative review of pathophysiology and management strategies
CONCLUSION: Sarcopenic obesity and hypertension present significant challenges to global public health. Addressing arterial stiffness is paramount in managing these conditions effectively. Lifestyle modifications, including weight management and physical activity, remain central to the treatment of sarcopenic obesity, while additional research is needed to explore potential pharmacological options.PMID:37712242 | DOI:10.4415/ANN_23_03_10
Source: Ann Ist Super Sanita - September 15, 2023 Category: Biomedical Science Authors: Mihaela Jurdana Lovro Žiberna Source Type: research

Characteristics and Predictors of Apparent Treatment Resistant Hypertension in Real-World Populations Using Electronic Health Record-Based Data
CONCLUSIONS: In two large, diverse real-world populations, we observed similar comorbidities and predictors of aTRH as prior studies. In the future, these results may be used to improve healthcare professionals' understanding of aTRH predictors and associated comorbidities.PMID:37712350 | DOI:10.1093/ajh/hpad084
Source: American Journal of Hypertension - September 15, 2023 Category: Cardiology Authors: Eissa Jafari Rhonda M Cooper-DeHoff Mark B Effron William R Hogan Caitrin W McDonough Source Type: research