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Condition: Hypertension

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Total 62632 results found since Jan 2013.

Establishment and Validation of Risk Prediction Model for Postpartum Hemorrhage for Pregnant Women ≥35 Years of Age in Natural Delivery
CONCLUSIONS: The PPH risk-prediction model for vaginal delivery for pregnant women ≥35 years of age showed that a greater age, pregnancy-induced hypertension, a lower prelabor FIB, a longer third stage of labor, and a higher birth weight for the newborn were significantly related to the incidence of PPH and that its use could be clinically helpful.PMID:37708560
Source: Alternative Therapies in Health and Medicine - September 14, 2023 Category: Complementary Medicine Authors: Chunxue Yang Hongxia Wu Source Type: research

Clinical Application Value of left Ventricular Pressure-Strain Loop Examination of Myocardial Dysfunction in Patients with Hypertension at Various Risk Levels
CONCLUSION: Left ventricular pressure-strain loop can be used to evaluate changes in left ventricular myocardial work of essential hypertension patients in the early stage and with different risk stratifications.PMID:37708557
Source: Alternative Therapies in Health and Medicine - September 14, 2023 Category: Complementary Medicine Authors: Shaochun Li Fanxuan Wang Rongan Zeng Qun Lei Xionghong Liu Source Type: research

Correlation Study of Chronic Renal Insufficiency and Long-Term Prognosis of Patients with Acute Ischemic Cerebral Apoplexy After Intravenous rt-PA Thrombolysis
CONCLUSION: CKD is an independent risk factor for acute ischemic cerebral apoplexy patients with intravenous rt-PA thrombolysis.PMID:37708556
Source: Alternative Therapies in Health and Medicine - September 14, 2023 Category: Complementary Medicine Authors: Cui Zhao GuoMin Xie Source Type: research

α2δ-1 as a New Target for Immunosuppressant-Induced Hypertension
Circ Res. 2023 Sep 15;133(7):628-630. doi: 10.1161/CIRCRESAHA.123.323500. Epub 2023 Sep 14.NO ABSTRACTPMID:37708245 | PMC:PMC10513733 | DOI:10.1161/CIRCRESAHA.123.323500
Source: Circulation Research - September 14, 2023 Category: Cardiology Authors: Antentor Hinton Annet Kirabo Source Type: research

Outcome of obstructed total anamalous pulmonary venous connection (TAPVC) repair patients with milrinone versus milrinone and inhaled nitric oxide (INO): A prospective randomized observational study
CONCLUSION: Most of the patients with obstructed TAPVC had severe PAH. Management of severe PAH with a combination of milrinone with iNO had a better outcome than milrinone alone.PMID:37706383 | PMC:PMC10284474 | DOI:10.4103/aca.aca_56_22
Source: Annals of Cardiac Anaesthesia - September 14, 2023 Category: Anesthesiology Authors: Srikanth Gujja Mrugesh Prajapati Tanya R Chuada Hemang Gandhi Varun Arora Vivek Kaul Sanjay Patel Source Type: research

Comparison of hyperoxia or normoxia resolution of intermittent hypoxia and intermittent hyperoxia episodes on liver histopathology, IGF-1, IGFBP-3, and GHBP in neonatal rats
CONCLUSIONS: Exposure to IH or intermittent hyperoxia during the first few weeks of life regardless of resolution in RA or hyperoxia is detrimental to the immature liver. These findings may suggest that interventions to prevent frequent fluctuations in oxygen saturation during early neonatal life remain a high priority.PMID:37708588 | DOI:10.1016/j.ghir.2023.101559
Source: Growth Hormone and IGF Research - September 14, 2023 Category: Endocrinology Authors: Charles L Cai Matthew Marcelino Jacob V Aranda Kay D Beharry Source Type: research

Gene-environment interactions that influence CVD, lipid traits, obesity, diabetes, and hypertension appear to be able to influence gene therapy
Mol Aspects Med. 2023 Sep 11;94:101213. doi: 10.1016/j.mam.2023.101213. Online ahead of print.ABSTRACTMost mind boggling diseases are accepted to be impacted by both genetic and environmental elements. As of late, there has been a flood in the improvement of different methodologies, concentrate on plans, and measurable and logical techniques to examine gene-environment cooperations (G × Es) in enormous scope studies including human populaces. The many-sided exchange between genetic elements and environmental openings has long charmed the consideration of clinicians and researchers looking to grasp the complicated starting...
Source: Molecular Medicine - September 13, 2023 Category: Molecular Biology Authors: Moataz Dowaidar Source Type: research

Model-Informed Dosing Regimen of Ticagrelor in Chinese Patients with Acute Coronary Syndrome
Clin Pharmacol Ther. 2023 Sep 13. doi: 10.1002/cpt.3048. Online ahead of print.ABSTRACTThe exposure to ticagrelor is higher in the East Asian population compared to the Caucasian population, thus, East Asians have an increased risk of bleeding. We developed a population pharmacokinetic model of ticagrelor based on a randomized 3 × 3 crossover study in healthy subjects. The area under concentration-time curve (AUC) of Chinese patients with acute coronary syndrome was simulated based on this model. Following this, eight machine learning methods were used to construct bleeding risk models. Variables included in the final ble...
Source: Clinical Pharmacology and Therapeutics - September 13, 2023 Category: Drugs & Pharmacology Authors: Yaxin Liu Yun Kuang Min Hai Cheng Cui Dongyang Liu Guoping Yang Source Type: research

Association of Obesity Based on Different Metabolic Status with Risk of Gout Occurrence in Patients: A National Study
CONCLUSION: When metabolic abnormalities were present, obesity induced a higher risk of gout. Different components of metabolic abnormalities had different effects on the risk of gout occurrence, and the number of metabolic abnormalities was closely related to the risk of gout occurrence. Follow-up and intervention methods targeting obesity and metabolic abnormalities should be considered for patients with gout.PMID:37702179 | DOI:10.2174/1871530323666230911140635
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - September 13, 2023 Category: Endocrinology Authors: Yanyan Wang Xiude Fan Xu Hou Luna Liu Shizhan Ma Junming Han Zhixiang Wang Source Type: research

Rethinking the distribution of sleep services: discrepancy of obstructive sleep apnoea in rural compared with metropolitan men in Australia - a large national survey
CONCLUSION: This study highlights the need to ensure adequate services in rural areas, given the higher proportion of men diagnosed with, or at risk of, OSA in rural areas. OSA is also associated with an increase risk of comorbidities such as heart disease, hypertension and diabetes, which are diseases also seen more prevalently in rural men. Rethinking the distribution of healthcare services will go some way to addressing this problem.PMID:37700451 | DOI:10.22605/RRH7704
Source: Rural Remote Health - September 13, 2023 Category: Rural Health Authors: Lauren A Booker Brad Hodge Timothy C Skinner Source Type: research

Association of interleukin 6 and uric acid levels in patients with type 2 diabetes mellitus
Bioinformation. 2022 Dec 31;18(12):1136-1140. doi: 10.6026/973206300181136. eCollection 2022.ABSTRACTType 2 Diabetes Mellitus (T2DM) patients with coronary artery disease (CAD) coupled with hypertension (HTN) are leading cause of morbidity and mortality. Association of Interleukin 6 and uric acid levels can be used for early detection of CAD in patients with T2DM. This cross sectional study included 120 study participants, were sub grouped into three Group 1: controls (n=30), Group 2: CAD, HTN without T2DM (n=30) and Group 3: CAD, HTN with T2DM (n=30). Basic biochemical, clinical and experimental parameters were analysed a...
Source: Bioinformation - September 13, 2023 Category: Bioinformatics Authors: Setty Raghav Gutlur Nagarajaiah Pallavi Somashekar Rangaswamaiah Hareesh Ganesh Veluri Source Type: research

Machine learning approaches for biomarker discovery to predict large-artery atherosclerosis
In this study, we propose a new method integrates multiple machine learning algorithms and feature selection method to handle multidimensional data. Among the six machine learning models, logistic regression (LR) model exhibited the best prediction performance. The value of area under the receiver operating characteristic curve (AUC) was 0.92 when 62 features were incorporated in the external validation set for the LR model. In this model, LAA could be well predicted by clinical risk factors including body mass index, smoking, and medications for controlling diabetes, hypertension, and hyperlipidemia as well as metabolites...
Source: Atherosclerosis - September 13, 2023 Category: Cardiology Authors: Ting-Hsuan Sun Chia-Chun Wang Ya-Lun Wu Kai-Cheng Hsu Tsong-Hai Lee Source Type: research

Variability in Plasma Lipids Between Intensive Statin Therapy and Conventional-Dose Statins Combined with Ezetimibe Therapy in Patients with Coronary Atherosclerosis Disease
In this study, we aimed to examine the variability in plasma lipids under two different lipid-lowering regimens (intensive statin therapy versus the combination of conventional-dose statins with ezetimibe). In total, we have retrospectively examined 1275 patients with CAD from January 2009 to April 2019 and divided them into two groups: intensive statin group and conventional-dose statins combined with ezetimibe group. All patients were followed up for at least 1 year. Lipid variability was verified by standard deviation (SD), coefficient of variation (CV), and variability independent of mean (VIM) triple methods. Multiple...
Source: Atherosclerosis - September 13, 2023 Category: Cardiology Authors: Jinhua Jin Liwen Shan Manjun Wang Lu Liu Tian Xu Duanbin Li Zhezhe Chen Xianglan Liu Wenbin Zhang Ya Li Source Type: research

Exploring the Effects of Elevated Serum Uric Acid Levels on Hypertension: A Scoping Review of Hyperuricemia
Cureus. 2023 Aug 12;15(8):e43361. doi: 10.7759/cureus.43361. eCollection 2023 Aug.ABSTRACTHypertension (HTN) is a global health concern due to its increasing prevalence and association with life-threatening complications. An intriguing area of investigation in HTN research is the relationship between HTN and hyperuricemia. In light of this, we conducted a review to summarize the relevant studies exploring the link between elevated serum uric acid (sUA) concentration and new-onset HTN. Through a comprehensive search of PubMed Central, MEDLINE, and PubMed databases, we identified 20 studies that met our inclusion criteria. T...
Source: Atherosclerosis - September 13, 2023 Category: Cardiology Authors: Tyagi J Ubhadiya Nidhi Dubey Mihir H Sojitra Karan Shah Saumya Joshi Siddharth Kamal Gandhi Priyansh Patel Source Type: research

Heart rate variability and cardiovascular risk factors in patients with rheumatoid arthritis: A longitudinal study
CONCLUSION: This study showed that patients with RA have autonomic imbalance both at an early stage of the disease and after five years, despite anti-rheumatic medication, but no correlation between HRV and inflammation markers were observed. Reduced HRV was also significantly negatively correlated with increased SBP. Hypertension is a common finding in patients with RA. Thus, significant decline of HRV could be a useful early marker for development of hypertension in patients with RA.PMID:37703773 | DOI:10.1016/j.autneu.2023.103119
Source: Autonomic Neuroscience - September 13, 2023 Category: Neuroscience Authors: Sofia Erelund Anna S ödergren Urban Wiklund Nina Sundstr öm Source Type: research