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Condition: Hypertension
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Total 62632 results found since Jan 2013.
Male kidney-specific BMAL1 knockout mice are protected from Potassium-deficient, high salt diet-induced blood pressure increases
Am J Physiol Renal Physiol. 2023 Sep 14. doi: 10.1152/ajprenal.00126.2023. Online ahead of print.ABSTRACTThe circadian clock protein BMAL1 is a transcription factor that impacts kidney function, including blood pressure (BP) control. Previously, we showed that male, but not female, kidney-specific cadherin Cre positive BMAL1 knockout mice (KS-BMAL1 KO) exhibit lower BP compared to littermate controls. The goal of this study was to determine the BP phenotype and immune response in male KS-BMAL1 KO in response to a low potassium, high salt diet (LKHS). BP, renal inflammatory markers and immune cells were measured in male mic...
Source: Am J Physiol Renal P... - September 14, 2023 Category: Urology & Nephrology Authors: G Ryan Crislip Hannah M Costello Alexandria Juffre Kit-Yan Cheng I Jeanette Lynch Jermaine G Johnston Charles B Drucker Phillip Bratanatawira Annanya Agarwal Victor M Mendez Ryanne S Thelwell Lauren G Douma Charles S Wingo Abdel A Alli Yogesh M Scindia Mi Source Type: research
Probiotics for pancreatic β-cell function: from possible mechanism of action to assessment of effectiveness
Crit Rev Microbiol. 2023 Sep 13:1-21. doi: 10.1080/1040841X.2023.2257776. Online ahead of print.ABSTRACTType 2 diabetes (T2D) is a metabolic disease characterized by chronic hyperglycemia because of insulin resistance (IR) and\or pancreatic β-cell dysfunction. Last century research showed that gut microbiota has a direct effect on metabolism and metabolic diseases. New studies into the human microbiome and its connection with the host is making it possible to develop new therapies for a wide variety of diseases. Inflammation is a well-known precursor to metabolic syndrome, which increases the risk of hypertension, viscera...
Source: Critical Reviews in Microbiology - September 14, 2023 Category: Microbiology Authors: Nazarii Kobyliak Maria Khomenko Tetyana Falalyeyeva Alexandra Fedchenko Oleksii Savchuk Yuliya Tseyslyer Liudmyla Ostapchenko Source Type: research
Male kidney-specific BMAL1 knockout mice are protected from Potassium-deficient, high salt diet-induced blood pressure increases
Am J Physiol Renal Physiol. 2023 Sep 14. doi: 10.1152/ajprenal.00126.2023. Online ahead of print.ABSTRACTThe circadian clock protein BMAL1 is a transcription factor that impacts kidney function, including blood pressure (BP) control. Previously, we showed that male, but not female, kidney-specific cadherin Cre positive BMAL1 knockout mice (KS-BMAL1 KO) exhibit lower BP compared to littermate controls. The goal of this study was to determine the BP phenotype and immune response in male KS-BMAL1 KO in response to a low potassium, high salt diet (LKHS). BP, renal inflammatory markers and immune cells were measured in male mic...
Source: Am J Physiol Renal P... - September 14, 2023 Category: Urology & Nephrology Authors: G Ryan Crislip Hannah M Costello Alexandria Juffre Kit-Yan Cheng I Jeanette Lynch Jermaine G Johnston Charles B Drucker Phillip Bratanatawira Annanya Agarwal Victor M Mendez Ryanne S Thelwell Lauren G Douma Charles S Wingo Abdel A Alli Yogesh M Scindia Mi Source Type: research
α2δ-1 as a New Target for Immunosuppressant-Induced Hypertension
Circ Res. 2023 Sep 15;133(7):628-630. doi: 10.1161/CIRCRESAHA.123.323500. Epub 2023 Sep 14.NO ABSTRACTPMID:37708245 | DOI:10.1161/CIRCRESAHA.123.323500
Source: Circulation Research - September 14, 2023 Category: Cardiology Authors: Antentor Hinton Annet Kirabo Source Type: research
Impaired vascular β-adrenergic relaxation in spontaneously hypertensive rats: The differences between conduit and resistance arteries
In conclusion, attenuated β-adrenergic vasodilatation of conduit arteries of SHR but similar β-adrenergic relaxation of resistance mesenteric arteries from WKY and SHR and their similar BP response to β-adrenergic agonists do not support major role of altered β-adrenergic vasodilatation for high BP in genetic hypertension.PMID:37708986 | DOI:10.1016/j.ejphar.2023.176045
Source: European Journal of Pharmacology - September 14, 2023 Category: Drugs & Pharmacology Authors: Pavol Valovi č Michal Behuliak Ivana Van ěčková Josef Zicha Source Type: research
Male kidney-specific BMAL1 knockout mice are protected from Potassium-deficient, high salt diet-induced blood pressure increases
Am J Physiol Renal Physiol. 2023 Sep 14. doi: 10.1152/ajprenal.00126.2023. Online ahead of print.ABSTRACTThe circadian clock protein BMAL1 is a transcription factor that impacts kidney function, including blood pressure (BP) control. Previously, we showed that male, but not female, kidney-specific cadherin Cre positive BMAL1 knockout mice (KS-BMAL1 KO) exhibit lower BP compared to littermate controls. The goal of this study was to determine the BP phenotype and immune response in male KS-BMAL1 KO in response to a low potassium, high salt diet (LKHS). BP, renal inflammatory markers and immune cells were measured in male mic...
Source: American Journal of Physiology. Renal Physiology - September 14, 2023 Category: Physiology Authors: G Ryan Crislip Hannah M Costello Alexandria Juffre Kit-Yan Cheng I Jeanette Lynch Jermaine G Johnston Charles B Drucker Phillip Bratanatawira Annanya Agarwal Victor M Mendez Ryanne S Thelwell Lauren G Douma Charles S Wingo Abdel A Alli Yogesh M Scindia Mi Source Type: research
Outcome of obstructed total anamalous pulmonary venous connection (TAPVC) repair patients with milrinone versus milrinone and inhaled nitric oxide (INO): A prospective randomized observational study
CONCLUSION: Most of the patients with obstructed TAPVC had severe PAH. Management of severe PAH with a combination of milrinone with iNO had a better outcome than milrinone alone.PMID:37706383 | PMC:PMC10284474 | DOI:10.4103/aca.aca_56_22
Source: Annals of Cardiac Anaesthesia - September 14, 2023 Category: Anesthesiology Authors: Srikanth Gujja Mrugesh Prajapati Tanya R Chuada Hemang Gandhi Varun Arora Vivek Kaul Sanjay Patel Source Type: research
Comparison of hyperoxia or normoxia resolution of intermittent hypoxia and intermittent hyperoxia episodes on liver histopathology, IGF-1, IGFBP-3, and GHBP in neonatal rats
CONCLUSIONS: Exposure to IH or intermittent hyperoxia during the first few weeks of life regardless of resolution in RA or hyperoxia is detrimental to the immature liver. These findings may suggest that interventions to prevent frequent fluctuations in oxygen saturation during early neonatal life remain a high priority.PMID:37708588 | DOI:10.1016/j.ghir.2023.101559
Source: Growth Hormone and IGF Research - September 14, 2023 Category: Endocrinology Authors: Charles L Cai Matthew Marcelino Jacob V Aranda Kay D Beharry Source Type: research
Impaired vascular β-adrenergic relaxation in spontaneously hypertensive rats: The differences between conduit and resistance arteries
In conclusion, attenuated β-adrenergic vasodilatation of conduit arteries of SHR but similar β-adrenergic relaxation of resistance mesenteric arteries from WKY and SHR and their similar BP response to β-adrenergic agonists do not support major role of altered β-adrenergic vasodilatation for high BP in genetic hypertension.PMID:37708986 | DOI:10.1016/j.ejphar.2023.176045
Source: European Journal of Pharmacology - September 14, 2023 Category: Drugs & Pharmacology Authors: Pavol Valovi č Michal Behuliak Ivana Van ěčková Josef Zicha Source Type: research
Comparison of hyperoxia or normoxia resolution of intermittent hypoxia and intermittent hyperoxia episodes on liver histopathology, IGF-1, IGFBP-3, and GHBP in neonatal rats
CONCLUSIONS: Exposure to IH or intermittent hyperoxia during the first few weeks of life regardless of resolution in RA or hyperoxia is detrimental to the immature liver. These findings may suggest that interventions to prevent frequent fluctuations in oxygen saturation during early neonatal life remain a high priority.PMID:37708588 | DOI:10.1016/j.ghir.2023.101559
Source: Growth Hormone and IGF Research - September 14, 2023 Category: Endocrinology Authors: Charles L Cai Matthew Marcelino Jacob V Aranda Kay D Beharry Source Type: research
Probiotics for pancreatic β-cell function: from possible mechanism of action to assessment of effectiveness
Crit Rev Microbiol. 2023 Sep 13:1-21. doi: 10.1080/1040841X.2023.2257776. Online ahead of print.ABSTRACTType 2 diabetes (T2D) is a metabolic disease characterized by chronic hyperglycemia because of insulin resistance (IR) and\or pancreatic β-cell dysfunction. Last century research showed that gut microbiota has a direct effect on metabolism and metabolic diseases. New studies into the human microbiome and its connection with the host is making it possible to develop new therapies for a wide variety of diseases. Inflammation is a well-known precursor to metabolic syndrome, which increases the risk of hypertension, viscera...
Source: Critical Reviews in Microbiology - September 14, 2023 Category: Microbiology Authors: Nazarii Kobyliak Maria Khomenko Tetyana Falalyeyeva Alexandra Fedchenko Oleksii Savchuk Yuliya Tseyslyer Liudmyla Ostapchenko Source Type: research
Establishment and Validation of Risk Prediction Model for Postpartum Hemorrhage for Pregnant Women ≥35 Years of Age in Natural Delivery
CONCLUSIONS: The PPH risk-prediction model for vaginal delivery for pregnant women ≥35 years of age showed that a greater age, pregnancy-induced hypertension, a lower prelabor FIB, a longer third stage of labor, and a higher birth weight for the newborn were significantly related to the incidence of PPH and that its use could be clinically helpful.PMID:37708560
Source: Alternative Therapies in Health and Medicine - September 14, 2023 Category: Complementary Medicine Authors: Chunxue Yang Hongxia Wu Source Type: research
Clinical Application Value of left Ventricular Pressure-Strain Loop Examination of Myocardial Dysfunction in Patients with Hypertension at Various Risk Levels
CONCLUSION: Left ventricular pressure-strain loop can be used to evaluate changes in left ventricular myocardial work of essential hypertension patients in the early stage and with different risk stratifications.PMID:37708557
Source: Alternative Therapies in Health and Medicine - September 14, 2023 Category: Complementary Medicine Authors: Shaochun Li Fanxuan Wang Rongan Zeng Qun Lei Xionghong Liu Source Type: research
Correlation Study of Chronic Renal Insufficiency and Long-Term Prognosis of Patients with Acute Ischemic Cerebral Apoplexy After Intravenous rt-PA Thrombolysis
CONCLUSION: CKD is an independent risk factor for acute ischemic cerebral apoplexy patients with intravenous rt-PA thrombolysis.PMID:37708556
Source: Alternative Therapies in Health and Medicine - September 14, 2023 Category: Complementary Medicine Authors: Cui Zhao GuoMin Xie Source Type: research
