This page shows you your search results in order of date. This is page number 10.

Order by Relevance | Date

Total 1980994 results found since Jan 2013.

GSE210888 Enhancer retargeting at the PAX5/ZCCHC7 locus
Contributors : Lijing Wu ; Wanwei Zhang ; Gerson Rothschild ; Junghyun Lim ; Rebecca Leeman-Neill ; Uttiya BasuSeries Type : OtherOrganism : Homo sapiens2 kinds of SU-DHL-10 cell clones (Pax5-TSS2mut/deletion) were generated to investigate enhancer relocation, we campared 4C-seq data between the Pax5-TSS2mut/deletion clones and wild type SU-DHL-10.
Source: GEO: Gene Expression Omnibus - September 22, 2023 Category: Genetics & Stem Cells Tags: Other Homo sapiens Source Type: research

GSE210497 SARS-CoV-2 pathogenesis mediated by E protein's PBM was prevented by modulators of CFTR function
Contributors : Jose M Honrubia ; Francisco J Guti érrez-Álvarez ; Alejandro Sanz ; Diego Muñoz ; Ezequiel González ; Carlos Castaño-Rodríguez ; Jorge Ripoll ; Ana Esteban ; Raúl Fernández-Delgado ; Juan C Oliveros ; Stanley Perlman ; Paul McCray ; Luis EnjuanesSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe three human deadly coronaviruses (CoVs) (SARS-CoV, MERS-CoV and SARS-CoV-2) have infected around eight thousand, two thousand six hundred and 262 million people so far (December 2021), causing the death of 10%, 37% and 2% of them, respectively, so their implication in h...
Source: GEO: Gene Expression Omnibus - September 22, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research

GSE206868 Epithelial Gab1 calibrates RIPK3-dependent necroptosis to prevent intestinal inflammation
We report that epithelial-Gab1 deficiency in mice facilitates inflammatory cell infiltration and aggravates colonic inflammation in colitis microenvironment
Source: GEO: Gene Expression Omnibus - September 22, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research

Unprecedented Multifunctionality in Novel Monophase Micro/Nanostructured Ti ‐Zn Alloy
This study highlights the remarkable multifunctionality of an unexplored monophase of structurally and thermally stable micro/nanostructured Ti0.5Zn0.5 alloy. The integrated glucose-sensing-triggered energy-storage-device, featuring high-quality Ti0.5Zn0.5 electrodes, exhibits outstanding biocompatibility, antiwear characteristics, anticorrosive behavior, mechanical robustness, and antibacterial activity. This alloy shows promise for applications in durable, wearable, and point-of-care diagnostic tools for human and animal healthcare, and tracking applications. AbstractIt is always challenging to integrate multiple functio...
Source: Small - September 22, 2023 Category: Nanotechnology Authors: Hajeesh Kumar Vikraman, Jeena George, Rence P. Reji, Guru Prasad Kuppuswamy, Sanjay. D. Sutar, Anita Swami, Sharmiladevi Ramamoorthy, Anandhakumar Sundaramurthy, Sumit Pramanik, Surya Velappa Jayaraman, Suresh Perumal, Yuvaraj Sivalingam, S. R Tags: Research Article Source Type: research

A new scaffold-free tumoroid model provides a robust preclinical tool to investigate invasion and drug response in Renal Cell Carcinoma
Cell Death & Disease, Published online: 22 September 2023; doi:10.1038/s41419-023-06133-zA new scaffold-free tumoroid model provides a robust preclinical tool to investigate invasion and drug response in Renal Cell Carcinoma
Source: Cell death and disease - September 22, 2023 Category: Internal Medicine Authors: Irinka S éraudie Catherine Pillet Beatrice Cesana Pauline Bazelle Florian Jeanneret Bertrand Evrard Fr édéric Chalmel Assilah Bouzit Christophe Battail Jean-Alexandre Long Jean Luc Descotes Claude Cochet Odile Filhol Source Type: research

FBXW2 suppresses breast tumorigenesis by targeting AKT-Moesin-SKP2 axis
Cell Death & Disease, Published online: 22 September 2023; doi:10.1038/s41419-023-06127-xFBXW2 suppresses breast tumorigenesis by targeting AKT-Moesin-SKP2 axis
Source: Cell death and disease - September 22, 2023 Category: Internal Medicine Authors: Ganesh Kumar Barik Osheen Sahay Anindya Mukhopadhyay Rajesh Kumar Manne Sehbanul Islam Anup Roy Somsubhra Nath Manas Kumar Santra Source Type: research

M2 macrophage inhibits the antitumor effects of Lenvatinib on intrahepatic cholangiocarcinoma
ConclusionCompared with M1, M2 macrophages can inhibit the anti-tumor effect of Lenvatinib on cholangiocarcinoma through immune regulation, which may be related to the tumor angiogenesis factor effect of M2 macrophage.
Source: Frontiers in Immunology - September 22, 2023 Category: Allergy & Immunology Source Type: research

Genetic selection for reduced health treatment costs in Holstein cows: implications from a long-term study
The objective of this study was to estimate genetic parameters of health treatment cost of Holstein cows from producer-recorded health treatments in 8 herds over an 8-yr period of time. Genetic parameters of health treatment cost were estimated in first (n = 2,214), second (n = 1,487) and third (n = 800) parities of US Holstein cows. The health treatments were uniformly defined and consistently recorded by 8 high-performance dairy herds in Minnesota from 2008 to 2015. A fixed treatment cost was assigned to 14 types of health treatments, and the cost included the mean veterinary expense obtained from the veterinary clinics ...
Source: Frontiers in Genetics - September 22, 2023 Category: Genetics & Stem Cells Source Type: research

Genes, Vol. 14, Pages 1832: Radiogenomic Features of GIMAP Family Genes in Clear Cell Renal Cell Carcinoma: An Observational Study on CT Images
This study demonstrates CT imaging features of GIMAP expression in ccRCC. These results could allow the collection of data on GIMAP expression through a CT-approach and could be used for the development of a targeted therapy.
Source: Genes - September 22, 2023 Category: Genetics & Stem Cells Authors: Federico Greco Andrea Panunzio Alessandro Tafuri Caterina Bernetti Vincenzo Pagliarulo Bruno Beomonte Zobel Arnaldo Scardapane Carlo Augusto Mallio Tags: Article Source Type: research

Viruses, Vol. 15, Pages 1976: Extracellular Vesicles as a Translational Approach for the Treatment of COVID-19 Disease: An Updated Overview
a Di Domenico Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a global pandemic in the years 2020–2022. With a high prevalence, an easy route of transmission, and a long incubation time, SARS-CoV-2 spread quickly and affected public health and socioeconomic conditions. Several points need to be elucidated about its mechanisms of infection, in particular, its capability to evade the immune system and escape from neutralizing antibodies. Extracellular vesicles (EVs) are phospholipid bilayer-delimited particles that are involved in cell-to-cell communication; they contain biological infor...
Source: Viruses - September 22, 2023 Category: Virology Authors: Enrica Serretiello Andrea Ballini Annafrancesca Smimmo Marina Acunzo Mariarosaria Raimo Stefania Cantore Marina Di Domenico Tags: Review Source Type: research

Viruses, Vol. 15, Pages 1975: Alterations in Patients & rsquo; Clinical Outcomes and Respiratory Viral Pathogen Activity following the COVID-19 Pandemic
Conclusions: We have demonstrated a reduction in the detection of several viruses, which might be due to the increase in public awareness toward infection protection measures after the COVID-19 pandemic.
Source: Viruses - September 22, 2023 Category: Virology Authors: Khaled Al Oweidat Ahmad A. Toubasi Ahmad Alghrabli Yasmeen Khater Noor Saleh Asma S. Albtoosh Rawan Shafeek Batarseh Tags: Article Source Type: research

Host microbiome in tuberculosis: disease, treatment, and immunity perspectives
Tuberculosis (TB), an airborne pulmonary disease caused by Mycobacterium tuberculosis (M. tb), poses an unprecedented health and economic burden to most of the developing countries. Treatment of TB requires prolonged use of a cocktail of antibiotics, which often manifest several side effects, including stomach upset, nausea, and loss of appetite spurring on treatment non-compliance and the emergence of antibiotic resistant M. tb. The anti-TB treatment regimen causes imbalances in the composition of autochthonous microbiota associated with the human body, which also contributes to major side effects. The microbiota residing...
Source: Frontiers in Microbiology - September 22, 2023 Category: Microbiology Source Type: research

Proteome level analysis of drug-resistant Prevotella melaninogenica for the identification of novel therapeutic candidates
In conclusion, our study reported novel drug and vaccine targets and designed a multi-epitope vaccine against the P. melaninogenica infection. Further experimental validation will help open new avenues in the treatment of this multi-drug-resistant pathogen.
Source: Frontiers in Microbiology - September 22, 2023 Category: Microbiology Source Type: research

A novel oncolytic virus-based biomarker participates in prognosis and tumor immune infiltration of glioma
ConclusionOur research uncovered a critical role of PTBP1 in outcomes and immune cell infiltration of glioma patients, particularly in those with LGG.
Source: Frontiers in Microbiology - September 22, 2023 Category: Microbiology Source Type: research

Editorial: Perspectives on the ultrastructure and cell biology of parasitic protists
Source: Frontiers in cellular and infection microbiology - September 22, 2023 Category: Microbiology Source Type: research