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Girl, 8, gets kidney transplant without need for life-long drugs in UK-first
The stem cell transplant performed at London's Great Ormond Street (Gosh), means the eight-year-old's body accepted the organ as her own, sparing her a lifetime of medication.
Source: the Mail online | Health - September 21, 2023 Category: Consumer Health News Source Type: news
Self-buckling and self-writhing of semi-flexible microorganisms
Soft Matter, 2023, Advance Article DOI: 10.1039/D3SM00572K, PaperWilson Lough, Douglas B. Weibel, Saverio E. Spagnolie Motility of multiflagellated cells requires a delicate balance between flagellar activity, geometry, and mechanical properties of the cell body. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Soft Matter latest articles - September 21, 2023 Category: Chemistry Authors: Wilson Lough Source Type: research
Piet Borst Wins a Lasker Award for Scientific Excellence
This year's Lasker~Koshland Award for Special Achievement was awarded to Piet Borst for his stellar work on cell organelles, trypanosomes, and cancer drug resistance.
Source: The Scientist - September 21, 2023 Category: Science Tags: News News & Opinion Source Type: news
Associations Between Volunteering, STEM Backgrounds, and Information-Processing Skills in Adult Populations of the United States
AbstractVolunteering, STEM education and occupation, and information-processing skills such as literacy, numeracy, and digital problem-solving skills are important indicators of a nation ’s well-being as they represent civic engagement, economic development, and the human capital of the population. Although these critical social indicators have been previously examined in silos, the interrelationships are yet to be examined in the adult populations in the United States. The curren t study analyzed the 2012/2014/2017 U.S. Program for the International Assessment of Adult Competencies (PIAAC) data of adults aged between 25...
Source: Social Indicators Research - September 21, 2023 Category: International Medicine & Public Health Source Type: research
Cutting cartel recruitment could be the only way to reduce Mexico ’s violence
For decades, the Mexican government has been fighting a losing war against dozens of cartels involved in drug trading, human trafficking, extortion, and other crimes. Even though thousands of cartel members land in prison each year, cartel-related violence has continued to grow: The number of homicides resulting from the organizations fighting one another—including thousands of innocent bystanders caught in their crossfire each year—tripled between 2006 and 2018.
Now, researchers have developed a mathematical model of cartel recruitment and losses that hints at a better way out of this cycle of violence. The study...
Source: Science of Aging Knowledge Environment - September 21, 2023 Category: Geriatrics Source Type: research
Results from Human Clinical Trials Do Not Support Metformin as a Longevity Drug
The SENS Research Foundation staff have carried out the public service of extensively discussing and dismantling the evidence commonly cited in support of metformin as a way to modestly slow aging, showing that said evidence is problematic, to say the least. Metformin might make life modestly better for diabetics, but it doesn't slow aging. This view of the human data matches the poor quality of the animal model data, in which metformin makes a poor showing in comparison to the robust data for a modest slowing of aging that is produced by the use of, say, mTOR inhibitors, or the practice of calorie restriction.
Rega...
Source: Fight Aging! - September 21, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Redefining Money: America ’s digital currency dilemma
As the United States House Financial Services Committee looks to further impede the introduction of a digital dollar, where does this resistance to a CBDC stem from?#cbdc
Source: Reuters: Health - September 21, 2023 Category: Consumer Health News Source Type: news
Hsa_circ_0102899 promotes epithelial –mesenchymal transition in non-small cell lung cancer
Conclusioncirc_0102899 promotes EMT and metastasis in NSCLC by regulating the miR-885-5p/EIF4G2 axis.
Source: Clinical and Translational Oncology - September 21, 2023 Category: Cancer & Oncology Source Type: research
ALDH2 activation attenuates oxygen –glucose deprivation/reoxygenation-induced cell apoptosis, pyroptosis, ferroptosis and autophagy
ConclusionsCollectively, our results implied that ALDH2 attenuated OGD/R-induced cell apoptosis, pyroptosis, ferroptosis and autophagy to promote cell viability in HT22 cells and mouse cortical neurons.
Source: Clinical and Translational Oncology - September 21, 2023 Category: Cancer & Oncology Source Type: research
AKAP12 promotes cancer stem cell-like phenotypes and activates STAT3 in colorectal cancer
ConclusionThis study suggests Colorectal CSCs overexpress AKAP12 and maintain stem cell characteristics through the
AKAP12/PKC/STAT3 pathway. AKAP12 may be an important therapeutic target for blocking the development of colorectal
cancer in the field of cancer stem cells.
Source: Clinical and Translational Oncology - September 21, 2023 Category: Cancer & Oncology Source Type: research
MTF1 has the potential as a diagnostic and prognostic marker for gastric cancer and is associated with good prognosis
ConclusionMTF1 is relatively lowly expressed in gastric cancer. MTF1 is also an independent prognostic factor for gastric cancer patients and is associated with good prognosis. It has the potential to be a diagnostic and prognostic marker for gastric cancer.
Source: Clinical and Translational Oncology - September 21, 2023 Category: Cancer & Oncology Source Type: research
Induction of perineural invasion in salivary adenoid cystic carcinoma by circular RNA RNF111
ConclusionTaken together, circ-RNF111 stimulates PNI in SACC by miR-361-5p/HMGB2 axis and may serve as a potential therapeutic target for SACC.
Source: Clinical and Translational Oncology - September 21, 2023 Category: Cancer & Oncology Source Type: research
Dipeptidyl peptidase 4 inhibitor reduces tumor-associated macrophages and enhances anti-PD-L1-mediated tumor suppression in non-small cell lung cancer
ConclusionsAnagliptin can enhance PD-L1 blockade efficacy in NSCLC by inhibiting macrophage differentiation and M2 macrophage polarization, and combination therapy may be a promising strategy for treating PD-L1 blockade therapy-resistant patients with NSCLC.
Source: Clinical and Translational Oncology - September 21, 2023 Category: Cancer & Oncology Source Type: research
Towards an atomic scale understanding on the early-stage deterioration mechanism of LSCF
J. Mater. Chem. A, 2023, Accepted Manuscript DOI: 10.1039/D3TA04585D, PaperShu-Sheng Liu, Katherine Develos-Bagarinao, Riyan Achmad Budiman, Tomohiro Ishiyama, Haruo Kishimoto, Katsuhiko Yamaji The early-stage degradation behaviour of a porous lanthanum strontium cobalt ferrite (LSCF) cathode in a solid oxide fuel cell is investigated at a low temperature of 600 °C by operating... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - J. Mater. Chem. latest articles - September 21, 2023 Category: Chemistry Authors: Shu-Sheng Liu Source Type: research
IRP Lectures
Ada Lovelace Day, held every year on the second Tuesday of October, was created to celebrate one of the first woman computer programmers. It is an international celebration of the achievements of women in science, technology, engineering and mathematics (STEM). It aims to increase the roles of women within the STEM sectors and support women already working in STEM.
Source: NLM General Announcements - September 21, 2023 Category: Databases & Libraries Source Type: news
