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Child in Montana becomes third person this year to be struck down with SWINE FLU after close contact with infected pigs at county fair
A third case of swine flu in the US this year was confirmed in an unnamed patient who had recently been in contact with pigs at a fair. The Centers for Disease Control announced it in a Tweet.
Source: the Mail online | Health - September 22, 2023 Category: Consumer Health News Source Type: news

Montana child becomes third American this year to be struck down with SWINE FLU after close contact with infected pigs at county fair
A third case of swine flu in the US this year was confirmed in an unnamed patient who had recently been in contact with pigs at a fair. The Centers for Disease Control announced it in a Tweet.
Source: the Mail online | Health - September 22, 2023 Category: Consumer Health News Source Type: news

Sliding on cortical shell: Biomechanical characterization of the vertebral cannulation for pedicle screw insertion
Characterizing pedicle cannulation enables to predict extra pedicular perforation. Influence of bone mineral density and patient-specific morphology on pedicle cannulation has been highlighted together with a comparison of swine and cadaver models.
Source: Clinical Biomechanics - September 22, 2023 Category: Orthopaedics Authors: Lugdivine Leblond, Yves Godio-Raboutet, Florent Tomi, Yann Glard, Raphael La Greca, Thomas Clement, Morgane Evin Source Type: research

Viruses, Vol. 15, Pages 1980: Animal Models for Henipavirus Research
olsey Hendra virus (HeV) and Nipah virus (NiV) are zoonotic paramyxoviruses in the genus Henipavirus (HNV) that emerged nearly thirty years ago. Outbreaks of HeV and NiV have led to severe respiratory disease and encephalitis in humans and animals characterized by a high mortality rate. Despite the grave threat HNVs pose to public health and global biosecurity, no approved medical countermeasures for human use currently exist against HeV or NiV. To develop candidate vaccines and therapeutics and advance the field’s understanding of HNV pathogenesis, animal models of HeV and NiV have been instrumental and ...
Source: Viruses - September 22, 2023 Category: Virology Authors: Declan D. Pigeaud Thomas W. Geisbert Courtney Woolsey Tags: Review Source Type: research

Understanding the interface between European wild boar (Sus scrofa) and domestic pigs (Sus scrofa domesticus) in Sweden through a questionnaire study
In recent years, the wildlife/livestock interface has attracted increased attention due to disease transmission between wild and domestic animal populations. The ongoing spread of African swine fever (ASF) in ...
Source: Acta Veterinaria Scandinavica - September 22, 2023 Category: Veterinary Research Authors: Linda Ernholm, Karl St åhl, Aleksija Neimanis, Stefan Widgren and Susanna Sternberg-Lewerin Tags: Research Source Type: research

Seroimmunotyping of African swine fever virus
The extreme genetic and immunobiological heterogeneity exhibited by the African swine fever virus (ASFV) has been a significant impediment in the development of an efficacious vaccine against this disease. Consequently, the lack of internationally accepted protocols for the laboratory evaluation of candidate vaccines has become a major concern within the scientific community. The formulation of such protocols necessitates the establishment of a consensus at the international level on methods for the determination of homologous and heterologous isolates/strains of ASFV. The present article provides a comprehensive descripti...
Source: Frontiers in Microbiology - September 22, 2023 Category: Microbiology Source Type: research

The 3' end of the coding region of senecavirus A contains a highly conserved sequence that potentially forms a stem-loop structure required for virus rescue
AbstractSenecavirus A (SVA) can cause a vesicular disease in swine. It is a positive-strand RNA virus belonging to the genusSenecavirus in the familyPicornaviridae. Positive-strand RNA viruses possess positive-sense, single-stranded genomes whose untranslated regions (UTRs) have been reported to containcis-acting RNA elements. In the present study, a total of 100 SVA isolates were comparatively analyzed at the genome level. A highly conserved fragment (HCF) was found to be located in the 3D sequence and to be close to the 3' UTR. The HCF was computationally predicted to form a stem-loop structure. Eight synonymous mutation...
Source: Archives of Virology - September 22, 2023 Category: Virology Source Type: research

Subsistence swine farming: seroprevalence and risk factors associated with Lawsonia intracellularis infection in the state of Minas Gerais Brazil in 2016
In conclusion, anti-L. intracellularis antibodies were widely dispersed in subsistence pig farming ’s in Minas Gerais, indicating a wide circulation of the agent in this type of production system. The interactions of animals raised close to peri-urban areas, extensively, and close to landfills are risk factors for spread of PPE.
Source: Tropical Animal Health and Production - September 22, 2023 Category: Veterinary Research Source Type: research

A CRISPR-Cas12a-based platform facilitates the detection and serotyping of Streptococcus suis serotype 2
In this study, we developed a high-fidelity detection and serotyping platform for S. suis serotype 2 based on recombinase polymerase amplification (RPA) and a clustered regularly interspaced short palindromic repeat (CRISPR)-Cas12a system called Cards-SSJ/K. Cards-SSJ had a detection limit of 10 CFU, takes <60 min, and no cross-reaction was found with other S. suis serotypes, closely related Streptococcus spp., or common pig pathogens, and Cards-SSK could differentiate serotype 2 from serotype 1/2. Results from Cards-SSJ and qPCR were equivalent in detecting S. suis serotype 2 in tissue samples. Analysis indicated that ...
Source: Talanta - September 21, 2023 Category: Chemistry Authors: Lu Wang Jing Sun Jiyu Zhao Jieyu Bai Yueling Zhang Yao Zhu Wanjiang Zhang Chunlai Wang Paul R Langford Siguo Liu Gang Li Source Type: research

Recovery of Extracorporeal Lungs Using Cross-Circulation with Injured Recipient Swine
Lung transplantation remains limited by the shortage of healthy organs. Cross-circulation with a healthy swine recipient provides a durable physiologic environment to recover injured donor lungs. In a clinical application, a recipient awaiting lung transplantation could be placed on cross-circulation to recover damaged donor lungs, enabling eventual transplantation. Our objective was to assess the ability of recipient swine with respiratory compromise to tolerate cross-circulation and support recovery of donor lungs subjected to extended cold ischemia.
Source: The Journal of Thoracic and Cardiovascular Surgery - September 21, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Panpan Chen, Julie Van Hassel, Meghan R. Pinezich, Mohamed Diane, Maria R. Hudock, Sarah R. Kaslow, Olimpia P. Gavaudan, Kenmond Fung, Mandy L. Kain, Hermogenes Lopez, Anjali Saqi, Brandon A. Guenthart, Ahmed E. Hozain, Alexander Romanov, Matthew Bacchett Source Type: research

Population structure and genetic diversity of Streptococcus suis isolates obtained from the United States
This study applied whole genome sequencing and cgMLST-based typing to evaluate the population structure and genetic relatedness among S. suis isolates obtained within the U.S. The established high-resolution phylogenomic framework revealed extensive genomic variation and diversity among the sampled S. suis isolates, with isolates from the U.S. and from countries outside the U.S. found interspersed in the phylogeny. S. suis isolates obtained within the U.S. did not cluster by state or geographic location, however, isolates with similar serotypes, both obtained from within and outside the U.S., generally clustered together. ...
Source: Frontiers in Microbiology - September 21, 2023 Category: Microbiology Source Type: research

VETRIMEC FOR CATTLE AND SWINE (ivermectin) injection, solution MWI/VetOne
Updated Date: Wed, 20 Sep 2023 00:00:00 EDT
Source: DailyMed Drug Label Updates - September 20, 2023 Category: Drugs & Pharmacology Source Type: alerts

Viruses, Vol. 15, Pages 1955: Seasonal Occurrence of African Swine Fever in Wild Boar and Domestic Pigs in EU Member States
Sauter-Louis Since 2007, African swine fever (ASF) has spread widely within Europe and beyond. Most affected countries recorded outbreaks in domestic pigs and cases in wild boar. Outbreak data from 2014 to 2021 were used to investigate the seasonal pattern of ASF in domestic pigs and wild boar across affected member states of the European Union, since knowledge of seasonal patterns may provide the potential to adapt prevention, surveillance and control during times of increased risk. In domestic pigs, a yearly peak was observed in many European countries in summer (predominantly in July and August). In wild boar, the p...
Source: Viruses - September 20, 2023 Category: Virology Authors: Lisa Rogoll Ann-Kathrin G üttner Katja Schulz Hannes Bergmann Christoph Staubach Franz J. Conraths Carola Sauter-Louis Tags: Article Source Type: research

Viruses, Vol. 15, Pages 1959: Fitness Determinants of Influenza A Viruses
ins Influenza A (IAV) is a major human respiratory pathogen that causes illness, hospitalizations, and mortality annually worldwide. IAV is also a zoonotic pathogen with a multitude of hosts, allowing for interspecies transmission, reassortment events, and the emergence of novel pandemics, as was seen in 2009 with the emergence of a swine-origin H1N1 (pdmH1N1) virus into humans, causing the first influenza pandemic of the 21st century. While the 2009 pandemic was considered to have high morbidity and low mortality, studies have linked the pdmH1N1 virus and its gene segments to increased disease in humans and animal mod...
Source: Viruses - September 20, 2023 Category: Virology Authors: Emily Fate Griffin Stephen Mark Tompkins Tags: Review Source Type: research

Interleukin-17 producing cells in swine induced by microbiota during the early postnatal period - a brief research report
Interleukin-17A (IL-17) is a pro-inflammatory cytokine involved in the immune response to many pathogens playing also a role in certain chronic and autoimmune diseases. The presented study focused on the early postnatal development of IL-17 producing cells in swine. In agreement with previous studies, αβ T-helper (CD3+CD4+) and γδ T (CD3+TCRγδ+) cells were found to be the major producers of IL-17. In newborn conventional piglets, αβ T-helper cells positive for IL-17 were almost undetectable, but their frequency increased markedly with age in all issues examined, i.e., blood, spleen, and mesenteric lymph nodes (MLN)...
Source: Frontiers in Immunology - September 20, 2023 Category: Allergy & Immunology Source Type: research