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Translocation of CdS nanoparticles in maize (Zea mays L.) plant and its effect on metabolic response
Chemosphere. 2023 Sep 14:140189. doi: 10.1016/j.chemosphere.2023.140189. Online ahead of print.ABSTRACTCadmium sulfide nanomaterials are of great concern because of their potential toxicity and unavoidable releases due to multiple commercial applications of nanoparticles (NPs). Commercial NPs act as mediators of damage to plant cells and pose potential toxicity to plants and human health. In the current study, investigated the phytotoxicology, absorption, translocation, antioxidant enzyme activity, and metabolic profiles of maize (Zea mays L.) seedlings exposed to different hydroponic treatments for fifteen days. The diffe...
Source: Chemosphere - September 16, 2023 Category: Chemistry Authors: Hameed Ullah Wang Zheng Yanqing Sheng Source Type: research
The linkage between microRNA and cancer and its delivery as cancer therapy: A mini-review
Cell Mol Biol (Noisy-le-grand). 2023 Jul 31;69(7):7-18. doi: 10.14715/cmb/2023.69.7.2.ABSTRACTThe central dogma of molecular biology was no longer "central" after ground-breaking discoveries conveyed gene expression involves more complex physiological functions in cancer pathogenesis over the last decade. MicroRNAs (miRNAs) are short non-coding RNA that regulate gene expression, affecting key molecular pathways involved in sustaining the proliferative signalling for tumour development, evasion of cellular death, invasion, angiogenesis, as well as metastasis in a plethora of cancer types. MiRNA expression is dysregulated in...
Source: Mol Biol Cell - September 16, 2023 Category: Molecular Biology Authors: Syed Umar Faruq Syed Najmuddin Ammar Akram Kamarudin Suraya Abdul Sani Mohd Nor Faiz Norrrahim Nur 'Atikah Abdul Latif Lucky Goh Poh Wah Source Type: research
Effects of Cr(VI) oxyanion, humic acid and solution chemistry on the aggregation and colloidal stability of green synthesized chlorapatite nanoparticles
This study investigated the aggregation kinetics and colloidal stability of nClAP as a function of pH, humic acid (HA), Cr(VI) oxyanions, monovalent and divalent electrolytes. Results showed that pH values from 5 to 9 had a notable impact on the aqueous behaviors of nClAP. The addition of HA made the zeta potential (ZP) of nClAP more negative and thus enhanced nClAP stability through electrostatic and steric effects. Similarly, the adsorption of Cr(VI) on the surface of nClAP created a physical barrier and negative charge, improving the stability of nClAP by inducing steric force. Lower ZP and hydrodynamic diameter (HDD) r...
Source: Chemosphere - September 16, 2023 Category: Chemistry Authors: Mengjia Zhang Wei Wei Yang Chen Xuan Han Source Type: research
The linkage between microRNA and cancer and its delivery as cancer therapy: A mini-review
Cell Mol Biol (Noisy-le-grand). 2023 Jul 31;69(7):7-18. doi: 10.14715/cmb/2023.69.7.2.ABSTRACTThe central dogma of molecular biology was no longer "central" after ground-breaking discoveries conveyed gene expression involves more complex physiological functions in cancer pathogenesis over the last decade. MicroRNAs (miRNAs) are short non-coding RNA that regulate gene expression, affecting key molecular pathways involved in sustaining the proliferative signalling for tumour development, evasion of cellular death, invasion, angiogenesis, as well as metastasis in a plethora of cancer types. MiRNA expression is dysregulated in...
Source: Cellular and Molecular Biology - September 16, 2023 Category: Molecular Biology Authors: Syed Umar Faruq Syed Najmuddin Ammar Akram Kamarudin Suraya Abdul Sani Mohd Nor Faiz Norrrahim Nur 'Atikah Abdul Latif Lucky Goh Poh Wah Source Type: research
Development of Green-Synthesized Carbon-Based Nanoparticle for Prevention of Surface Wound Biofilm
Appl Biochem Biotechnol. 2023 Sep 16. doi: 10.1007/s12010-023-04695-4. Online ahead of print.ABSTRACTThe development of microbial biofilm occurs with the adherence of the microbial cells on biotic and abiotic surfaces with the help of pili and with extracellular polymeric substances. The surfaces on which biofilm formation take place can be inert, abiotic, or biotic. The sessile microbial cells behave differently from their planktonic counterpart. The biofilm developed by Alcaligenes faecalis is responsible for the development of skin and soft-tissue infection. It was observed that green-synthesized carbon nanoparticles (N...
Source: Applied Biochemistry and Biotechnology - September 16, 2023 Category: Biochemistry Authors: Miaolin Yang Zhi Li Source Type: research
Removal of an agricultural herbicide (2,4-Dichlorophenoxyacetic acid) using magnetic nanocomposite: A combined experimental and modeling studies
This study focused on modeling the removal of one of the widely used agricultural herbicides known as 2,4-Dichlorophenoxyacetic acid (2,4-D) using polypyrrole-coated Fe2O3 nanoparticles (Fe2O3@PPy). The Fe2O3@PPy nanocomposite was synthesized by surface-coating the Tabebuia aurea leaf extract synthesized Fe2O3 nanoparticles with polypyrrole. After characterization, the adsorptive potential of the nanocomposite for removing 2,4-D from aqueous solution was examined. Central composite design (CCD) was employed for optimizing the adsorption, revealing an adsorption efficiency of 90.65% at a 2,4-D concentration of 12 ppm, a dos...
Source: Environmental Research - September 16, 2023 Category: Environmental Health Authors: Sridevi H Ramananda Bhat M Raja Selvaraj Source Type: research
Effects of polyvinylchloride microplastics on the toxicity of nanoparticles and antibiotics to aerobic granular sludge: Nitrogen removal, microbial community and resistance genes
Environ Res. 2023 Sep 14:117151. doi: 10.1016/j.envres.2023.117151. Online ahead of print.ABSTRACTCopper oxide nanoparticles (CuO NPs) and ciprofloxacin (CIP) have ecological risk to humans and ecosystems. Polyvinylchloride microplastics (PVC MPs), as a representative of microplastics, may often coexist with CuO NPs and CIP in wastewater treatment systems due to their widespread application. However, the co-impact of PVC MPs in wastewater systems contained with CuO NPs and CIP on nitrogen removal and ecological risk is not clear. In this work, PVC MPs co-impacts on the toxicity of CuO NPs and CIP to aerobic granular sludge...
Source: Environmental Research - September 16, 2023 Category: Environmental Health Authors: Yu-Qi Li Bai-Hang Zhao Yu-Qing Zhang Xin-Yue Zhang Xiao-Tang Chen Hai-Shan Yang Source Type: research
Nanoparticles and nanofiltration for wastewater treatment: From polluted to fresh water
Environ Res. 2023 Sep 14:117114. doi: 10.1016/j.envres.2023.117114. Online ahead of print.ABSTRACTWater pollution poses significant threats to both ecosystems and human health. Mitigating this issue requires effective treatment of domestic wastewater to convert waste into bio-fertilizers and gas. Neglecting liquid waste treatment carries severe consequences for health and the environment. This review focuses on intelligent technologies for water and wastewater treatment, targeting waterborne diseases. It covers pollution prevention and purification methods, including hydrotherapy, membrane filtration, mechanical filters, r...
Source: Environmental Research - September 16, 2023 Category: Environmental Health Authors: Tomy Muringayil Joseph Hussein E Al-Hazmi Bogna Śniatała Amin Esmaeili Sajjad Habibzadeh Source Type: research
A novel magneto-mediated electrochemical biosensor integrated DNAzyme motor and hollow nanobox-like Pt@Ni-Co electrocatalyst as dual signal amplifiers for vanilla detection
Biosens Bioelectron. 2023 Sep 12;241:115690. doi: 10.1016/j.bios.2023.115690. Online ahead of print.ABSTRACTHerein, a novel magneto-mediated electrochemical aptasensor using the signal amplification technologies of DNAzyme motor and electrocatalyst for vanilla (VAN) detection was fabricated. The D/B duplex, formed by the DNAzyme motor that was each silenced by a blocker, and hairpin DNA1 (H1) containing adenosine ribonucleotide (rA) site were tethered on the sites of the gold nanoparticles@hollow porphyrinic-Metal-organic framework/polyethyleneimine-reduced graphene oxide (AuHPCN-222/PEI-rGO)-modified gold electrode (AuE)....
Source: Biosensors and Bioelectronics - September 16, 2023 Category: Biotechnology Authors: Jingyi Zhu Baoshan He Yao Liu Yuling Wang Jinshui Wang Ying Liang Huali Jin Min Wei Wenjie Ren Zhiguang Suo Yiwei Xu Source Type: research
Development of mucoadhesive Timolol loaded chitosan-nanocomposite to treat glaucoma
Int J Biol Macromol. 2023 Sep 14:126917. doi: 10.1016/j.ijbiomac.2023.126917. Online ahead of print.ABSTRACTTimolol Maleate is an aqueous soluble β-blocker antiglaucoma drug used to suppress intraocular pressure. Several commercially available ocular formulations are not effective in delivering to the target site due to their water-soluble property and low mucoadhesiveness. Hence, there is a requirement for a highly mucoadhesive drug-loaded nanocomposite to suppress intraocular pressure with enhanced bioavailability. Herein, we have prepared a mucoadhesive Timolol-loaded graphene quantum dot-chitosan-nanocomposite to trea...
Source: International Journal of Biological Macromolecules - September 16, 2023 Category: Biochemistry Authors: B N Kumara R Shambhu Yoon-Bo Shim Jayabalan Nirmal K Sudhakara Prasad Source Type: research
A novel self-assembled nanoplatform based on retrofitting poloxamer 188 for triple-negative breast cancer targeting treatment
In this study, a novel self-assembled nanoplatform was developed for active targeting of folate receptor-overexpressing triple-negative breast cancer. This platform, FPP NPs, was prepared by the retrofitted poloxamer 188 derivatives, resulting in nanoparticles with an appropriate size (<100 nm), good stability, and satisfactory biocompatibility. Cellular uptake and in vivo distribution studies showed that the FPP NPs had strong tumor cell uptake and active targeting capabilities. Furthermore, docetaxel (DTX) was loaded into FPP NPs in this research. The resulting DTX/FPP NPs exhibited high drug encapsulation efficiency ...
Source: Chemico-Biological Interactions - September 16, 2023 Category: Molecular Biology Authors: Xueyan Hou Yalin Guan Sisi He Zeqing Wu Jintao Bai Jingjing Xu Jingwen Wang Suyue Xu Huiqing Zhu Yanyan Yin Xue Yang Yongli Shi Source Type: research
Translocation of CdS nanoparticles in maize (Zea mays L.) plant and its effect on metabolic response
Chemosphere. 2023 Sep 14:140189. doi: 10.1016/j.chemosphere.2023.140189. Online ahead of print.ABSTRACTCadmium sulfide nanomaterials are of great concern because of their potential toxicity and unavoidable releases due to multiple commercial applications of nanoparticles (NPs). Commercial NPs act as mediators of damage to plant cells and pose potential toxicity to plants and human health. In the current study, investigated the phytotoxicology, absorption, translocation, antioxidant enzyme activity, and metabolic profiles of maize (Zea mays L.) seedlings exposed to different hydroponic treatments for fifteen days. The diffe...
Source: Chemosphere - September 16, 2023 Category: Chemistry Authors: Hameed Ullah Wang Zheng Yanqing Sheng Source Type: research
Effects of Cr(VI) oxyanion, humic acid and solution chemistry on the aggregation and colloidal stability of green synthesized chlorapatite nanoparticles
This study investigated the aggregation kinetics and colloidal stability of nClAP as a function of pH, humic acid (HA), Cr(VI) oxyanions, monovalent and divalent electrolytes. Results showed that pH values from 5 to 9 had a notable impact on the aqueous behaviors of nClAP. The addition of HA made the zeta potential (ZP) of nClAP more negative and thus enhanced nClAP stability through electrostatic and steric effects. Similarly, the adsorption of Cr(VI) on the surface of nClAP created a physical barrier and negative charge, improving the stability of nClAP by inducing steric force. Lower ZP and hydrodynamic diameter (HDD) r...
Source: Chemosphere - September 16, 2023 Category: Chemistry Authors: Mengjia Zhang Wei Wei Yang Chen Xuan Han Source Type: research
Progress in the treatment of drug-loaded nanomaterials in renal cell carcinoma
This article reviews the use of nanomaterials, such as liposomes, polymeric nanoparticles, nanocomposites, carbon nanomaterials, nanobubbles, nanomicelles, and mesoporous silica nanoparticles, for RCC treatment, and discusses their advantages and disadvantages.PMID:37716114 | DOI:10.1016/j.biopha.2023.115444
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 16, 2023 Category: Drugs & Pharmacology Authors: Jianyang Li Kunzhe Wu Jinmei Zhang Huan Gao Xiaohua Xu Source Type: research
Effects of polyvinylchloride microplastics on the toxicity of nanoparticles and antibiotics to aerobic granular sludge: Nitrogen removal, microbial community and resistance genes
Environ Res. 2023 Sep 14:117151. doi: 10.1016/j.envres.2023.117151. Online ahead of print.ABSTRACTCopper oxide nanoparticles (CuO NPs) and ciprofloxacin (CIP) have ecological risk to humans and ecosystems. Polyvinylchloride microplastics (PVC MPs), as a representative of microplastics, may often coexist with CuO NPs and CIP in wastewater treatment systems due to their widespread application. However, the co-impact of PVC MPs in wastewater systems contained with CuO NPs and CIP on nitrogen removal and ecological risk is not clear. In this work, PVC MPs co-impacts on the toxicity of CuO NPs and CIP to aerobic granular sludge...
Source: Cell Research - September 16, 2023 Category: Cytology Authors: Yu-Qi Li Bai-Hang Zhao Yu-Qing Zhang Xin-Yue Zhang Xiao-Tang Chen Hai-Shan Yang Source Type: research
