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Total 150319 results found since Jan 2013.

Size, Surface Properties, and Ion Release of Zinc Oxide Nanoparticles: Effects on Cytotoxicity, Dopaminergic Gene Expression, and Acetylcholinesterase Inhibition in Neuronal PC-12 Cells
Biol Trace Elem Res. 2023 Sep 15. doi: 10.1007/s12011-023-03832-8. Online ahead of print.ABSTRACTThe extensive applications of zinc oxide nanoparticles (ZnO NPs) have resulted in a substantial risk of human exposure. However, the knowledge of the toxicity of these NPs in the nervous system is still limited. A comparative analysis of ZnO NPs of various sizes and NPs of the same size, with and without surface coating, and the potential role of released zinc ions is yet to be thoroughly explored. As a result, we have studied the cellular toxicity of two different-sized ZnO NPs, ZnO-22 (22 nm) and ZnO-43 (43 nm), and NPs with ...
Source: Biological Trace Element Research - September 15, 2023 Category: Biology Authors: Jitendra Kumar Suthar Anuradha Vaidya Selvan Ravindran Source Type: research

Evaluation of the Therapeutic Effect of Curcumin-Conjugated Zinc Oxide Nanoparticles on Reserpine-Induced Depression in Wistar Rats
In conclusion, curcumin-conjugated zinc oxide nanoparticles demonstrate potent antidepressant effects, alleviating depressive-like behavior in rats. These findings support Zn(cur)O NPs as a promising therapeutic strategy for depression management, warranting further investigation and clinical validation.PMID:37713054 | DOI:10.1007/s12011-023-03849-z
Source: Biological Trace Element Research - September 15, 2023 Category: Biology Authors: Heba M Fahmy Fatmaalzahraa A Aboalasaad Ayman S Mohamed Fathi A Elhusseiny Yasser A Khadrawy Ahmed Elmekawy Source Type: research

Photoelectrocatalytic modification of nanofiltration membranes with SrF 2 /Ti 3 C 2 T x to simultaneously enhance heavy metal ions rejection and permeability
In this study, a water bath method was used to form SrF2/Ti3C2Tx (ST) nanoparticles on the surface of polyvinylidene fluoride (PVDF) membranes and an additional polyamide (PA) functional layer was formed at the interface by crosslinking. ST@PA composite NF membranes (STPP) with good photocatalytic performance were obtained. The separation and catalytic properties of the STPP membranes were controlled by the ST content, which modifies the surface structure and properties of the membranes. The membrane with optimal ST crosslinking exhibited a water contact angle of 50.8°, pure water flux of 24.6 L·m-2·h-1·bar-1, and reje...
Source: Chemosphere - September 15, 2023 Category: Chemistry Authors: Huiqi Zheng Xiaorong Meng Jiao Wu Danghao Liu Shanshan Huo Source Type: research

Fabrication of Nickel/Zinc Oxide Nanocomposites from Citrus sinensis Extract Prompts Apoptosis Through Impeding JAK/STAT3 Signaling in Gastric Cancer
In this study, we sought to fabricate nickel/zinc oxide nanocomposites utilizing Citrus sinensis (C. sinensis) peel extract (CS-Ni/ZnO NCs) and investigate their ability to impede the JAK/STAT3 signaling pathway in gastric cancer AGS cells. Different methods, including UV-Vis spectral analysis, FT-IR, XRD, FE-SEM, EDAX, DLS, and zeta potential, were used to characterize the fabricated CS-Ni/ZnO NCs. By measuring ROS, MMP, and apoptotic cell death using the appropriate fluorescence describing procedures, the anticancer potential of CS-Ni/ZnO NCs was examined against AGS cells. The synthesized CS-Ni/ZnO NCs displayed a rod s...
Source: Applied Biochemistry and Biotechnology - September 15, 2023 Category: Biochemistry Authors: Zhifei Li Zhongwei Sun Source Type: research

Storage stability of chocolate can be enhanced using locust protein-based film incorporated with E. purpurea flower extract-based nanoparticles
Ultrason Sonochem. 2023 Sep 7;100:106594. doi: 10.1016/j.ultsonch.2023.106594. Online ahead of print.ABSTRACTThe study aimed to develop a locust protein (Loct-Prot)-based film to enhance the lipid oxidative and storage stability of chocolate. The E. purpurea flower extract based-nanoparticles (EFNPs) were developed using ultrasonication (500 W and 20 kHz for 10 min) following a green method of synthesis. The EFPNs were incorporated at different levels [T0 (0%), T1 (1.0%), T2 (1.5%), and T3 (2.0%)] to impart bioactive properties to the Loct-Prot-based films which were used for packaging of white chocolate during 90 days tri...
Source: Ultrasonics Sonochemistry - September 15, 2023 Category: Chemistry Authors: Shubam Singh Hina F Bhat Sunil Kumar Rana Muhammad Aadil Maneesha S Mohan Charalampos Proestos Zuhaib F Bhat Source Type: research

Synthesis and evaluation of biological effects of modified graphene oxide nanoparticles containing Lawson (Henna extract) on gastric cancer cells
CONCLUSION: This study showed the efficacy of nanoparticles in inhibiting gastric cancer cells by relying on inhibiting angiogenesis.PMID:37715021 | DOI:10.1007/s11033-023-08797-4
Source: Molecular Biology Reports - September 15, 2023 Category: Molecular Biology Authors: Mohammed Abdullah Hamdan Alkwedhim Vahid Pouresmaeil Fatemeh Davoodi-Dehaghani Mobina Mahavar Masoud Homayouni Tabrizi Source Type: research

Unraveling the potential of M13 phages in biomedicine: Advancing drug nanodelivery and gene therapy
Environ Res. 2023 Sep 13:117132. doi: 10.1016/j.envres.2023.117132. Online ahead of print.ABSTRACTM13 phages possessing filamentous phage genomes offer the benefits of selective display of molecular moieties and delivery of therapeutic agent payloads with a tolerable safety profile. M13 phage-displayed technology for resembling antigen portions led to the discovery of mimetic epitopes that applied to antibody-based therapy and could be useful in the design of anticancer vaccines. To date, the excremental experiences have engaged the M13 phage in the development of innovative biosensors for detecting biospecies, biomolecule...
Source: Environmental Research - September 15, 2023 Category: Environmental Health Authors: Mahmood Fadaie Hassan Dianat-Moghadam Elham Ghafouri Shamsi Naderi Mohammad Hossein Darvishali Mahsa Ghovvati Hossein Khanahmad Maryam Boshtam Pooyan Makvandi Source Type: research

An appraisal of the utilization of natural gums as corrosion inhibitors: Prospects, challenges, and future perspectives
Int J Biol Macromol. 2023 Sep 13:126904. doi: 10.1016/j.ijbiomac.2023.126904. Online ahead of print.ABSTRACTNatural gums are macro compounds containing monosaccharide (sugar) units bonded by glycosidic to form long polymeric sugar chains of considerably high molecular weight. Natural gums are multifaceted in applications with the main areas being the food and pharmaceutical industries. The recent research interest in corrosion inhibitors is considering natural gums because of their abundance and ecological compatibility. Hence, this review takes a look at the use of natural gums in pure and modified forms in metals protect...
Source: International Journal of Biological Macromolecules - September 15, 2023 Category: Biochemistry Authors: Ukeme J Timothy Peace S Umoren Moses M Solomon Isaac O Igwe Saviour A Umoren Source Type: research

Bacterial cellulose composite hydrogel for pre-concentration and mass spectrometric detection of thiol-containing biomarker
Int J Biol Macromol. 2023 Sep 13:126855. doi: 10.1016/j.ijbiomac.2023.126855. Online ahead of print.ABSTRACTSimple soaking of bacterial cellulose (BC) membrane in carboxymethyl cellulose (CMC) solution yielded BC/CMC hydrogel having re-swellable property. Then, gold nanoparticles (AuNPs) were embedded in the BC/CMC hydrogel via in situ chemical reduction to form BC/CMC/AuNPs composite hydrogel. It was found that the composite hydrogel exhibited physical/chemical characteristics similar to those of BC. The AuNPs with an average diameter of 13 nm distributed uniformly within the BC/CMC matrix as verified by transmission elec...
Source: International Journal of Biological Macromolecules - September 15, 2023 Category: Biochemistry Authors: Panlop Lormaneenopparat Jutiporn Yukird Nadnudda Rodthongkum Voravee P Hoven Source Type: research

An application of carbohydrate polymers-based surface-modified gold nanoparticles for improved target delivery to liver cancer therapy - A systemic review
This article provides an update on using carbohydrate-based GNPs in liver cancer treatment, imaging, and drug administration. Selective surface modification of several carbohydrate types and further biological uses of GNPs are focused on.PMID:37714232 | DOI:10.1016/j.ijbiomac.2023.126889
Source: International Journal of Biological Macromolecules - September 15, 2023 Category: Biochemistry Authors: Abdullah R Alzahrani Ibrahim Abdel Aziz Ibrahim Naiyer Shahzad Imran Shahid Ibrahim M Alanazi Alaa Hisham Falemban Mohd Fahami Nur Azlina Source Type: research

Cobalt oxide-chitosan based nanocomposites: Synthesis, characterization and their potential pharmaceutical applications
Int J Biol Macromol. 2023 Sep 13:126856. doi: 10.1016/j.ijbiomac.2023.126856. Online ahead of print.ABSTRACTThis research aimed to prepare, characterize, and investigate the biological efficacy of chitosan‑cobalt (II) oxide hybrid nanocomposites against a variety of micrograms. Analytical methods, FTIR, SEM, XRD, and EDX, were utilized to thoroughly characterize the produced CS-CoO nanocomposite. In FTIR spectra, the presence of the chitosan peaks in addition to that of CoO at 681 and 558 cm-1 confirmed that CoO molecules interact with the chitosan backbone. Moreover, in the XRD measurements, significantly less chitosan ...
Source: International Journal of Biological Macromolecules - September 15, 2023 Category: Biochemistry Authors: Ali H Bashal Khaled D Khalil Ahmed M Abu-Dief Mohamed A El-Atawy Source Type: research

Lanthanum nanoparticle (La 2 O 3 )-loaded adsorbents for removal of hexavalent chromium: a kinetics, isotherm, and thermodynamic study
Environ Sci Pollut Res Int. 2023 Sep 16. doi: 10.1007/s11356-023-29834-6. Online ahead of print.ABSTRACTNanocomposite adsorbents for wastewater treatment gained popularity in recent times. In the present study, nanoparticles prepared from lanthanum have been loaded on the powdered form of aquatic plants Salvinia molesta (S. molesta) and Typha latifolia (T. latifolia). These new adsorbents were NPS (nanoparticle-loaded S. molesta) and NPT (nanoparticle-loaded T. latifolia). The batch study was carried out to assess the effect of several factors on the adsorption of Cr(VI) by novel adsorbents NPS and NPT. XRD, SEM, FTIR, EDX...
Source: Environmental Science and Pollution Research International - September 15, 2023 Category: Environmental Health Authors: Asha Singh Dinesh Arora Renu Bala Anil Khokhar Sunil Kumar Source Type: research

ZIF-8 @polycarbonate nanocomposite membranes for improved permeability and selectivity for hydrogen gas
Environ Sci Pollut Res Int. 2023 Sep 15. doi: 10.1007/s11356-023-29650-y. Online ahead of print.ABSTRACTThrough this work, we are reporting high-performance ZIF-8 @polycarbonate nanocomposite membranes with satisfactory structural stability for improving the gas separation performance. ZIF-8 nanoparticles were synthesised using the wet chemical route with cubic morphology and controlled size using CTAB as a surfactant. The membranes were prepared using the solution casting method by adding ZIF-8 filler at various concentrations. The synthesised filler material and MMMs were characterised through X-ray diffraction spectrosc...
Source: Environmental Science and Pollution Research International - September 15, 2023 Category: Environmental Health Authors: Prashant Choudhary Nishel Saini Myung Han Yoon Kamlendra Awasthi Kamakshi Pandey Source Type: research

Drug Delivery System Approaches for Rheumatoid Arthritis Treatment: A Review
In conclusion, nanocarrier-based drug delivery systems have emerged as a promising solution for improving the treatment of rheumatoid arthritis. Further advancements in nanotechnology hold promise for enhancing the efficacy and safety of RA therapies, offering new hope for patients suffering from this debilitating disease.PMID:37711105 | DOI:10.2174/1389557523666230913105803
Source: Mini Reviews in Medicinal Chemistry - September 15, 2023 Category: Chemistry Authors: Anushka Garhwal Priyadarshi Kendya Sakshi Soni Shivam Kori Vandana Soni Sushil Kumar Kashaw Source Type: research

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