This page shows you your search results in order of date. This is page number 8.
Order by Relevance | Date
Total 150319 results found since Jan 2013.
Do Nanoparticles of Calcium Disodium EDTA Minimize the Toxic Effects of Cadmium in Female Rats?
Biol Trace Elem Res. 2023 Sep 18. doi: 10.1007/s12011-023-03842-6. Online ahead of print.ABSTRACTThe present study aims to investigate the ability of CaNa2EDTA (ethylenediaminetetraacetic acid) macroparticles and nanoparticles to treat cadmium-induced toxicity in female rats and to compare their efficacies. Forty rats were divided into 4 equal groups: control, cadmium, cadmium + CaNa2EDTA macroparticles and Cd + CaNa2EDTA nanoparticles. Cadmium was added to the drinking water in a concentration of 30 ppm for 10 weeks. CaNa2EDTA macroparticles and nanoparticles (50 mg/kg) were intraperitoneally injected during the last 4 we...
Source: Biological Trace Element Research - September 18, 2023 Category: Biology Authors: Safa M Saleh Osama S El-Tawil Manal B Mahmoud Sahar S Abd El-Rahman Eiman M El-Saied Peter A Noshy Source Type: research
Photoactivatable base editors for spatiotemporally controlled genome editing in vivo
This study opens a promising way to improve the operability, safety, and precision of base editing.PMID:37722184 | DOI:10.1016/j.biomaterials.2023.122328
Source: Biomaterials - September 18, 2023 Category: Materials Science Authors: Quan Zou Yi Lu Bo Qing Na Li Ting Zhou Jinbin Pan Xuejun Zhang Xuening Zhang Yupeng Chen Shao-Kai Sun Source Type: research
Folate conjugated nanomedicines for selective inhibition of mTOR signaling in polycystic kidneys at clinically relevant doses
Biomaterials. 2023 Sep 13;302:122329. doi: 10.1016/j.biomaterials.2023.122329. Online ahead of print.ABSTRACTAlthough rapamycin is a very effective drug for rodents with polycystic kidney disease (PKD), it is not encouraging in the clinical trials due to the suboptimal dosages compelled by the off-target side effects. We here report the generation, characterization, specificity, functionality, pharmacokinetic, pharmacodynamic and toxicology profiles of novel polycystic kidney-specific-targeting nanoparticles (NPs). We formulated folate-conjugated PLGA-PEG NPs, which can be loaded with multiple drugs, including rapamycin (a...
Source: Biomaterials - September 18, 2023 Category: Materials Science Authors: Rajasekharreddy Pala Ayan K Barui Ashraf M Mohieldin Jing Zhou Surya M Nauli Source Type: research
Application of nanoparticles in Dentistry
Bioinformation. 2023 Jan 31;19(1):14-18. doi: 10.6026/97320630019014. eCollection 2023.ABSTRACTNanoparticles(NPs) are of particle sizes lesser than 100nm and are insoluble the field which deal with the handling of these particles is coined as "Nanotechnology" as their particle size is smaller, they can penetrate easily therefore they are applied in various medical fields, drug delivery and in dentistry as they have antimicrobial property, reduces friction, anti-inflammatory and antioxidant property. Many studies have been done to evaluate its application and its cytotoxicity by varying its concentration and various studies...
Source: Bioinformation - September 18, 2023 Category: Bioinformatics Authors: Sheloni Missier Mary Mahesh Ramakrishnan Saravana Dinesh Sudalaimani Paulpandian Shanmugam Rajeshkumar Jebilla Pringle Source Type: research
Fabrication of a Novel Co/CoO@Fe < sub > 2 < /sub > V < sub > 4 < /sub > O < sub > 13 < /sub > Composite Catalyst as a Photoanode for Enhanced Photoelectrochemical Water Oxidation
Chem Asian J. 2023 Sep 18:e202300537. doi: 10.1002/asia.202300537. Online ahead of print.ABSTRACTHerein, the synthesis of a novel composite photocatalyst, Co/CoO@Fe2 V4 O13 , is reported by the deposition of CoO metal oxide nanoparticles on the surface of Fe2 V4 O13 bimetallic oxide. The synthesised photocatalyst exhibited a band gap of roughly 1.8 eV, rendering it responsive to the complete visible light spectrum of the sun, thereby enabling optimal absorption of solar radiation. The Co/CoO@Fe2 V4 O13 composites demonstrated an enhanced photoelectrochemical water oxidation capacity compared to pristine Fe2 V4 O13 when exp...
Source: Chemistry, an Asian Journal - September 18, 2023 Category: Chemistry Authors: Mohd Asim Abuzar Khan Source Type: research
Multifunctional nanozyme-reinforced copper-coordination polymer nanoparticles for drug-resistance bacteria extinction and diabetic wound healing
CONCLUSIONS: The Cu-CPNs@EPL complex has impressive antioxidant properties and antibacterial effects, making it a promising solution for treating drug-resistant bacterial infections in chronic wounds. The complex's ability to neutralize multiple ROS and reduce ROS-induced inflammation can help relieve inflammation at the wound site. Schematic illustration of the ROS scavenging and bacteriostatic function induced by Cu-CPNs@EPL nanozyme in the treatment of MRSA-infected wounds.PMID:37723499 | PMC:PMC10506277 | DOI:10.1186/s40824-023-00429-z
Source: Cell Research - September 18, 2023 Category: Cytology Authors: Jiahui Zhao Tengfei Xu Jichao Sun Haitao Yuan Mengyun Hou Zhijie Li Jigang Wang Zhen Liang Source Type: research
Cell-nanocarrier drug delivery system: a promising strategy for cancer therapy
Drug Deliv Transl Res. 2023 Sep 18. doi: 10.1007/s13346-023-01429-1. Online ahead of print.ABSTRACTTumor targeting has been a great challenge for drug delivery systems. A number of nanotechnology-derived drug carriers have been developed for cancer treatment to improve efficacy and biocompatibility. Among them, the emergence of cell-nanocarriers has attracted great attention, which simulates cell function and has good biocompatibility. They can also escape the clearance of reticuloendothelial system, showing a long-cycle effect. The inherent tumor migration and tumor homing ability of cells increase their significance as t...
Source: Cell Research - September 18, 2023 Category: Cytology Authors: Jiefen Yang Xiongxi Shi Yanting Kuang Ruting Wei Lanni Feng Jianming Chen Xin Wu Source Type: research
A new solid phase extraction sorbent developed based on cyanopropyl functionalized silica nanoparticles for organophosphorus pesticides determination
Environ Res. 2023 Sep 16:117167. doi: 10.1016/j.envres.2023.117167. Online ahead of print.ABSTRACTIn this work, a simple sol-gel approach was used for the preparation of cyanopropyl (CNPr) functionalized silica nanoparticles (SiO2-CNPr) that tetraethoxysilane (TEOS) and cyanopropyltriethoxysilane (CNPrTEOS) used as precursors. This as-prepared SiO2-CNPr nanoparticle sorbent was first characterized using FESEM, EDX, FTIR, TGA, and BET techniques. Then, the SiO2-CNPr nanoparticle was applied as a new SPE sorbent for determining trace levels of OPPs in environmental water samples. To enhance the simultaneous extraction of non...
Source: Environmental Research - September 18, 2023 Category: Environmental Health Authors: Zahra Sotoudehnia Korrani Elham Khalili Hesam Kamyab Wan Aini Wan Ibrahim Haslenda Hashim Source Type: research
Ionic-Liquid-Based Nanofluids and Their Heat-Transfer Applications: A Comprehensive Review
Chemphyschem. 2023 Sep 18:e202300191. doi: 10.1002/cphc.202300191. Online ahead of print.ABSTRACTDue to their improved thermophysical characteristics, such as their strong ionic conductivity, negligible vapor pressure, and thermal stability at high temperatures, the ionic liquids (ILs) are being looked at viable contender for future heat transfer fluids. Additionally, the dispersing nanoparticles can further improve the thermophysical characteristics and thermal performance of ionic liquids, which is one of the emerging research interests to increase the heat transfer rates of the thermal devices. The latest investigations...
Source: Chemphyschem - September 18, 2023 Category: Chemistry Authors: Syam Sundar Lingala Source Type: research
Improvement and Regulation of Steviol Glycoside Biosynthesis in Stevia rebaudiana Bertoni
Gene. 2023 Sep 16:147809. doi: 10.1016/j.gene.2023.147809. Online ahead of print.ABSTRACTStevia rebaudiana Bertoni is a natural sweetener plant that is progressively used not only for its sweetening properties but also for its medicinal properties. The plant contains steviol glycoside (SG) which is reported to be up to 300 times sweeter than sucrose. The plant is said to have no side effects on human health and has been approved by FDA. On the basis of previous studies and available databases, this review discusses the extensive understanding of the different approaches for enhancements of SG in S. rebaudiana. To improve t...
Source: Gene - September 18, 2023 Category: Genetics & Stem Cells Authors: Pritom Biswas Ankita Kumari Arpan Modi Nitish Kumar Source Type: research
PNIPAM-stabilized cubosomes as fusogenic delivery nanovectors for anticancer applications
Colloids Surf B Biointerfaces. 2023 Sep 9;231:113532. doi: 10.1016/j.colsurfb.2023.113532. Online ahead of print.ABSTRACTIn recent years, lipid cubic nanoparticles have emerged as promising nanocarriers for drug delivery, due to the several advantages they exhibit with respect to other lipid systems. Here, we report on lipid cubic nanoparticles stabilized by PNIPAM-based amphiphilic block copolymers, specifically, poly(N, N-dimethylacrylamide)-block-poly(N-isopropylacrylamide) (PDMA-b-PNIPAM), as a new class of drug delivery systems (DDS). In vitro studies on the internalization efficiency of the DDS towards two types of h...
Source: Colloids and Surfaces - September 18, 2023 Category: Biotechnology Authors: Arianna Balestri Laure Gibot Heinz Amenitisch Lorenzo Cervelli Costanza Montis Barbara Lonetti Debora Berti Source Type: research
Molecular Complex of HSIM-loaded Polymeric Nanoparticles: Potential Carriers in Osteoporosis
CONCLUSION: Bone-targeting nanoparticles incorporating functionalized simvastatin can target bone. Thus, in order to distribute simvastatin subcutaneously for the treatment of osteoporosis, the developed nanoparticles may act as a promising approach.PMID:37718521 | DOI:10.2174/1389450124666230915092910
Source: Current Drug Targets - September 18, 2023 Category: Drugs & Pharmacology Authors: Malkiet Kaur Manju Nagpal Amarjot Kaur Grewal Samrat Chauhan Chander Parkash Dora Thakur Gurjeet Singh Source Type: research
SERS-substrates based on ZnO nanoflowers prepared by green synthesis
Anal Biochem. 2023 Sep 16:115328. doi: 10.1016/j.ab.2023.115328. Online ahead of print.ABSTRACTZnO nanoparticles (NPs) with a flower-like morphology, synthesized by an affordable colloidal route using an aqueous fungi extract of Ganoderma lucidum as a reducing agent and stabilizer, are investigated as SERS-substrate. Each "flower" has large effective surface that is preserved at packing particles into a dense film and thus exhibits an advantageous property for SERS and similar sensing applications. The mycoextract used in our low-cost and green synthesis as surface stabilizer allows subsequent deposition of metal NPs or la...
Source: Analytical Biochemistry - September 18, 2023 Category: Biochemistry Authors: Volodymyr Dzhagan Oleksandr Smirnov Mariia Kovalenko Oleksandr Gudymenko Nazar Mazur Olga Kapush Mykola Skoryk Yaroslav Pirko Alla Yemets Mykhailo Valakh Petro Shepeliavyi Volodymyr Yukhymchuk Source Type: research
Fe-NPs and Zn-NPs: Advancing Aquaculture Performance Through Nanotechnology
Biol Trace Elem Res. 2023 Sep 18. doi: 10.1007/s12011-023-03850-6. Online ahead of print.ABSTRACTAquaculture is a growing industry facing several challenges, including disease control, water quality management, and sustainable feed production. One potential solution to these challenges is the use of trace elements such as iron (Fe) and zinc (Zn), either in their conventional form or as nanoparticles (NPs). Aquatic animals need these micronutrients for normal growth, physiological processes, and overall health. In marine species, iron boosts development, immunity, and disease resistance. At the same time, zinc enhances meta...
Source: Biological Trace Element Research - September 18, 2023 Category: Biology Authors: Farkhanda Asad Navaira Batool Aiman Nadeem Shehar Bano Noshaba Anwar Rafia Jamal Shahbaz Ali Source Type: research
Multi-level biological responses of Daphnia magna exposed to settleable atmospheric particulate matter from metallurgical industries
Aquat Toxicol. 2023 Sep 9;263:106692. doi: 10.1016/j.aquatox.2023.106692. Online ahead of print.ABSTRACTMetallurgical industries are a continuous source of air pollution due to the amount of settleable particulate matter (SePM) they release. This SePM is a complex mixture formed by metallic nanoparticles and metals, which reach terrestrial and aquatic ecosystems and can be a significant source of contamination. The aim of this study was to evaluate the adverse effects of SePM at different levels of biological organization in order to estimate its ecological impacts on aquatic ecosystems. For this purpose, the crustacean Da...
Source: Aquatic Toxicology - September 18, 2023 Category: Toxicology Authors: Mar ía Pilar González Andrea Cordero-de-Castro David Salvatierra Rajaa Kholssi Marisa Narciso Fernandes Juli án Blasco Cristiano V M Ara újo Camilo Dias Seabra Pereira Source Type: research
