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Effect of obesity and hypothyroidism on hepcidin concentration in pregnancy - a pilot study using maternal and umbilical cord blood at delivery day
J Physiol Pharmacol. 2022 Oct;73(5). doi: 10.26402/jpp.2022.5.04. Epub 2023 Mar 16.ABSTRACTHepcidin is a primary regulator of iron metabolism in the human body. By promoting ferroportin degradation, hepcidin reduces intestinal iron absorption and its release from intracellular stores. In the course of pregnancy, gradually declining hepcidin concentrations encourage placental iron transfer, thereby providing the appropriate amount of iron for fetal development. Hence, we aimed to investigate changes in maternal and cord blood hepcidin and iron metabolism parameters in normal-weight (n=17) and obese (n=17) gestating women, a...
Source: J Physiol Pharmacol - March 21, 2023 Category: Drugs & Pharmacology Authors: M Wojciechowska O W Wisniewski E Pruszynska-Oszmalek H Krauss M Sassek N Leciejewska P Kolodziejski M Wilczak Source Type: research
