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Total 1132 results found since Jan 2013.

Cyclovirobuxine D pretreatment ameliorates septic heart injury through mitigation of ferroptosis
In conclusion, these findings suggest that CVB-D alleviated sepsis-induced cardiac iron toxicity by alleviating iron metabolism.PMID:37522059 | PMC:PMC10375449 | DOI:10.3892/etm.2023.12106
Source: Experimental and Therapeutic Medicine - July 31, 2023 Category: General Medicine Authors: Jianxin Wang Peng Guan Yu Chen Meng Xu Na Wang Ensheng Ji Source Type: research

Diagnosis and treatment of iron overload
Rev Med Interne. 2023 Jul 26:S0248-8663(23)00680-X. doi: 10.1016/j.revmed.2023.07.002. Online ahead of print.ABSTRACTEtiological investigation of hyperferritinemia includes a full clinical examination, with the measurement of waist circumference, and simple biological tests including transferrin saturation. The classification between hyperferritinemia without iron overload (inflammation, excessive alcohol intake, cytolysis, L-ferritin mutation) or with iron overload is then relatively easy. Dysmetabolic iron overload syndrome is the most common iron overload disease and is defined by an unexplained serum ferritin level ele...
Source: Revue de Medecine Interne - July 28, 2023 Category: Internal Medicine Authors: M Ruivard H Lobbes Source Type: research

Hyperferritinemia and non-HFE hemochromatosis: differential diagnosis and workup
Acta Gastroenterol Belg. 2023 Apr-Jun;86(2):356-359. doi: 10.51821/86.2.11249.ABSTRACTHyperferritinemia is a common reason for referral to a hepatogastroenterologist. The most frequent causes are not associated with iron overload (e.g. inflammatory diseases, alcohol abuse, metabolic syndrome, etc.). However, hyperferritinemia can also be caused by a genetic variant in one of the iron regulatory genes, called hereditary hemochromatosis, often but not always associated with iron overload. A variation in the human Hemostatic Iron Regulator protein (HFE) gene is the most common genotype, but many other variants have been descr...
Source: Acta Gastro-Enterologica Belgica - July 10, 2023 Category: Gastroenterology Authors: E Lommaert W Verlinden I Duysburgh T Holvoet J Schouten Source Type: research