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Hyperferritinemia and non-HFE hemochromatosis: differential diagnosis and workup
Acta Gastroenterol Belg. 2023 Apr-Jun;86(2):356-359. doi: 10.51821/86.2.11249.ABSTRACTHyperferritinemia is a common reason for referral to a hepatogastroenterologist. The most frequent causes are not associated with iron overload (e.g. inflammatory diseases, alcohol abuse, metabolic syndrome, etc.). However, hyperferritinemia can also be caused by a genetic variant in one of the iron regulatory genes, called hereditary hemochromatosis, often but not always associated with iron overload. A variation in the human Hemostatic Iron Regulator protein (HFE) gene is the most common genotype, but many other variants have been descr...
Source: Acta Gastro-Enterologica Belgica - July 10, 2023 Category: Gastroenterology Authors: E Lommaert W Verlinden I Duysburgh T Holvoet J Schouten Source Type: research
