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Total 26176 results found since Jan 2013.

Effect of the iridocorneal angle size on the diurnal pressure profile in a glaucoma suspect cohort and patients with glaucoma
ConclusionAn ICAS of larger than 10 ° in HCG or glaucoma patients with an open-angle does not influence the minimum, average, maximum or range of IOP. Additionally, an angle size larger than 10° does not allow the prediction of IOP changes in these two cohorts.
Source: International Ophthalmology - September 2, 2023 Category: Opthalmology Source Type: research

Fecal calprotectin as an intestinal inflammation marker is elevated in glaucoma
Conclusion: Elevated fecal calprotectin might indicate potential intestinal inflammation in glaucoma.PMID:37656013 | DOI:10.2217/bmm-2023-0352
Source: Future Medicine: Biomarkers in Medicine - September 1, 2023 Category: Internal Medicine Authors: Zuo Wang Hang Yuan Xiong Zhu Jinxia Wang Wenbo Xiu Yang Chen Gao Zhang Jing Fu Kun Peng An Li Donghua Liu Xijing Huang Chong He Fang Lu Source Type: research

Increasing Role of OCT in Glaucoma Diagnostics and Disease Progression
Understanding structural changes in the optic nerve head, peripapillary retina, and macula due to glaucoma is important not only for diagnosis and management but also for insight on glaucoma pathophysiology. Studies in experimental glaucoma have provided significant clues on the sequence of neuronal and nonneuronal events in these tissues that clinicians recognize as glaucomatous neuropathy. However, the limitations of experimental glaucoma regarding applicability to humans and limitations of clinical studies that do not permit adequate parallel clinical and histological analyses means that an inevitable knowledge gap exists.
Source: JAMA Ophthalmology - September 1, 2023 Category: Opthalmology Source Type: research

Glaucoma Following Cataract Surgery in Children —Finally, a Clue
Childhood cataract is among the more common treatable causes of childhood visual disability and blindness, representing some 10% to 15% of children enrolled globally in schools for blind individuals. Congenital cataracts are genetically heterogeneous with 234 entries on Online Mendelian Inheritance in Man using the search terms congenital cataract. They may be isolated, associated with other ocular anomalies such as microphthalmia or sclerocornea, or be a part of systemic disorders such as trisomy 21 or Lowe syndrome. Some are associated with metabolic conditions such as galactosemia or cerebrotendinous xanthomatosis that ...
Source: JAMA Ophthalmology - September 1, 2023 Category: Opthalmology Source Type: research

Three-Dimensional Structural Phenotype of the Optic Nerve Head as a Function of Glaucoma Severity
This cross-sectional study examines optical coherence tomography images to describe 3-dimensional structural differences in both connective and neural tissues of the optic nerve head using traditional clinician-defined and artificial intelligence approaches.
Source: JAMA Ophthalmology - September 1, 2023 Category: Opthalmology Source Type: research

GJA3 Genetic Variation and Autosomal Dominant Congenital Cataracts and Glaucoma Following Cataract Surgery
This genetic association study assesses the family members in a 4-generation pedigree with congenital cataracts caused by a GJA3 variant who have a remarkably high incidence of glaucoma following cataract surgery in early childhood.
Source: JAMA Ophthalmology - September 1, 2023 Category: Opthalmology Source Type: research

Deep Ocular Phenotyping Across Primary Open-Angle Glaucoma Genetic Burden
This cross-sectional study investigates how the phenotypic features of patients vary across genetic burden for primary open-angle glaucoma.
Source: JAMA Ophthalmology - September 1, 2023 Category: Opthalmology Source Type: research

Ocular surface and glaucoma, a mutual relationship. Practical suggestions for classification and management
Eur J Ophthalmol. 2023 Aug 30:11206721231199157. doi: 10.1177/11206721231199157. Online ahead of print.ABSTRACTThe chronic use of glaucoma medications could improve the development of an ocular comorbidity, the glaucoma therapy-related ocular surface disease. This could be related to the exposure of the conjunctiva to preservatives, but also active compounds such as prostaglandin analogues may improve the risk of ocular surface inflammation. Inflammation has a negative impact on tolerability and adherence to eyedrops and to the outcome of filtration surgery as well. A stratification of glaucoma patients based not only on v...
Source: European Journal of Ophthalmology - August 31, 2023 Category: Opthalmology Authors: Michele Figus Matteo Sacchi Gemma Caterina Rossi Silvia Babighian Jos é Manuel Benitez Del Castillo Laura de Polo Eugenio Melchionda Chiara Posarelli Source Type: research

Multiple (frontloaded) visual field tests increase identification of very slow mean deviation progression in glaucoma
CONCLUSIONS: Frontloading VF tests at 6-monthly intervals improve detection rates of MD progression in slowly progressive glaucoma patients compared with performing 1 test per visit at yearly intervals.PMID:37652089 | DOI:10.1016/j.jcjo.2023.07.023
Source: Canadian Journal of Ophthalmology - August 31, 2023 Category: Opthalmology Authors: Jack Phu Jeremy Tan Michael Kalloniatis Source Type: research

The Incidence and Risk Factors of Optic Nerve Damage of Posner-Schlossman Syndrome: A Meta-Analysis
CONCLUSION: A fraction of PSS patients ultimately develop GOND so physicians should not be highly optimistic about the prognosis of PSS patients and timely and effective treatment is very important. Patients of higher age, those with double eyes affected, and suffering from a long disease duration might be at a greater risk of developing GOND.PMID:37652409
Source: Alternative Therapies in Health and Medicine - August 31, 2023 Category: Complementary Medicine Authors: Lan Yu Liang Zhang Lu He Kunming Cui Qingsong Wu Source Type: research