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Total 26176 results found since Jan 2013.
Clinical Efficacy of Omidenepag Isopropyl for Primary Open-Angle Glaucoma, Normal Tension Glaucoma, or Ocular Hypertension: A Meta-Analysis
Journal of Ocular Pharmacology and Therapeutics, Ahead of Print.
Source: Journal of Ocular Pharmacology and Therapeutics - August 9, 2023 Category: Opthalmology Authors: Hou-Ting Kuo Cyuan-Yi Yeh Alan Y. Hsu Jennifer Hui-Chun Ho Chun-Ju Lin Yi-Yu Tsai Source Type: research
Risk Factors for Flat Anterior Chamber Requiring Intervention After Glaucoma Drainage Implant- a Retrospective Case-Controlled Study
To identify risk factors for flat anterior chamber that required additional intervention in the postoperative period (90 days) after uncomplicated Baerveldt Glaucoma Implant (BGI) surgery.
Source: American Journal of Ophthalmology - August 9, 2023 Category: Opthalmology Authors: Huda Sheheitli, Ann V. Quan, Elizabeth A. Vanner, Richard K. Parrish Tags: Original Articles Source Type: research
One-year outcomes of ab externo Xen45 gel stent implantation with an open conjunctiva approach in patients with open-angle glaucoma
CONCLUSIONS: Xen45 gel stent implantation with the open conjunctiva approach is effective in reducing IOP and glaucoma medication for over 1 year in patients with OAG.PMID:37553094 | DOI:10.3341/kjo.2023.0044
Source: Korean Journal of Ophthalmology : KJO - August 8, 2023 Category: Opthalmology Authors: Kwangeon Han Jiwoong Lee Sangwoo Moon Source Type: research
Profiling and factors associated with glaucoma diagnostic practice in sub-Saharan Africa-a cross sectional study of Nigerian and Ghanaian optometrists
Ghana and Nigeria are the two countries in Africa that currently run the Doctor of Optometry (OD) program in sub-Saharan Africa (SSA). Optometrists in these countries are licensed to provide glaucoma care. Des...
Source: BMC Ophthalmology - August 8, 2023 Category: Opthalmology Authors: Stephen Ocansey, Edgar Ekure, Uchechukwu L. Osuagwu, Bernadine N. Ekpenyong, Godwin Ovenseri-Ogbomo, Sylvester Kyeremeh, Kelechi C. Ogbuehi, Kingsley E. Agho, Khathutshelo P. Mashige, Antor O. Ndep and Kovin S. Naidoo Tags: Research Source Type: research
Retro-mode: a newer insight into dry age-related macular degeneration (AMD)
AbstractThe purpose of this study is to study the role of retro-mode (RM) in early detection and to compare it with other preexisting available modalities on multimodal imaging system in dry AMD. A prospective observational cross-sectional study was done between November 2020 and October 2021 which included 409 eyes of 207 patients. For study purpose, eyes were divided into 3 groups according to the size and number of the drusen, viz, group 1: No AMD, group 2: early AMD and group 3: intermediate AMD which was further divided into 2 subgroups, viz, subgroup A: eyes with drusen size 63 –125 μm and subgroup B: eyes with dr...
Source: Lasers in Medical Science - August 8, 2023 Category: Laser Surgery Source Type: research
Cataract, glaucoma, and diabetic retinopathy are independent risk factors affecting falls in the older adult with eye diseases - Ouyang S, Zhang X, Li H, Tang X, Ning X, Li R, Ke P, Li Y, Huang F, Liu B, Fang Y, Liang Y.
OBJECTIVES: Falls are the leading cause of injury-related hospitalization in older adult, presenting a significant public health concern. To examine the specific eye diseases for risk factors of falls in the older adult. METHODS: A total of 775 old...
Source: SafetyLit - August 7, 2023 Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news
Vision-related quality of life among 70-year-olds diagnosed with glaucoma - Johansson LH, Kalaboukhova L, Erhag HF, Skoog I, Zetterberg M.
PURPOSE: To evaluate the effect of glaucoma on vision-related quality of life (VRQoL), lifestyle, physical factors and socioeconomic status in a 70-year-old population in Gothenburg, Sweden. METHODS: Responses to questionnaires (N = 1182) betwe...
Source: SafetyLit - August 7, 2023 Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news
The efficient induction of human retinal ganglion-like cells provides a platform for studying optic neuropathies
Cell Mol Life Sci. 2023 Aug 4;80(8):239. doi: 10.1007/s00018-023-04890-w.ABSTRACTRetinal ganglion cells (RGCs) are essential for vision perception. In glaucoma and other optic neuropathies, RGCs and their optic axons undergo degenerative change and cell death; this can result in irreversible vision loss. Here we developed a rapid protocol for directly inducing RGC differentiation from human induced pluripotent stem cells (hiPSCs) by the overexpression of ATOH7, BRN3B, and SOX4. The hiPSC-derived RGC-like cells (iRGCs) show robust expression of various RGC-specific markers by whole transcriptome profiling. A functional asse...
Source: Cellular and Molecular Life Sciences : CMLS - August 4, 2023 Category: Cytology Authors: Roxanne Hsiang-Chi Liou Shih-Wei Chen Hui-Chen Cheng Pei-Chun Wu Yu-Fen Chang An-Guor Wang Ming-Ji Fann Yu-Hui Wong Source Type: research
Intravitreal bevacizumab improves trabeculectomy survival at 12 months: the bevacizumab in trabeculectomy study-a randomised clinical trial
CONCLUSION: Bevacizumab given as a single intravitreal dose during trabeculectomy with MMC resulted in improved surgical success as 12 months. Furthermore, bevacizumab was associated with a significant reduction in the need for additional medication or further surgery to achieve target IOP. Bevacizumab was also associated with larger blebs that were less inflamed and required fewer subsequent interventions.TRIAL REGISTRATION NUMBER: ACTRN12614000375651.PMID:37541768 | DOI:10.1136/bjo-2023-323526
Source: The British Journal of Ophthalmology - August 4, 2023 Category: Opthalmology Authors: John A Landers Sean Mullany Jamie E Craig Source Type: research
NAD < sup > + < /sup > metabolism and eye diseases: current status and future directions
Mol Biol Rep. 2023 Aug 4. doi: 10.1007/s11033-023-08692-y. Online ahead of print.ABSTRACTCurrently, there are no truly effective treatments for a variety of eye diseases, such as glaucoma, age-related macular degeneration (AMD), and inherited retinal degenerations (IRDs). These conditions have a significant impact on patients' quality of life and can be a burden on society. However, these diseases share a common pathological process of NAD+ metabolism disorders. They are either associated with genetically induced primary NAD+ synthase deficiency, decreased NAD+ levels due to aging, or enhanced NAD+ consuming enzyme activit...
Source: Molecular Biology Reports - August 4, 2023 Category: Molecular Biology Authors: Siyuan Liu Wenfang Zhang Source Type: research
Retracted: 23G Minimally Invasive Vitrectomy Combined with Glaucoma Drainage Valve Implantation and Phacoemulsification Cataract Extraction for Neovascular Glaucoma Secondary to Proliferative Diabetic Retinopathy with Vitreous Hemorrhage
Comput Math Methods Med. 2023 Jul 26;2023:9868749. doi: 10.1155/2023/9868749. eCollection 2023.ABSTRACT[This retracts the article DOI: 10.1155/2022/7393661.].PMID:37538480 | PMC:PMC10396716 | DOI:10.1155/2023/9868749
Source: Computational and Mathematical Methods in Medicine - August 4, 2023 Category: Statistics Authors: Computational And Mathematical Methods In Medicine Source Type: research
NAD < sup > + < /sup > metabolism and eye diseases: current status and future directions
Mol Biol Rep. 2023 Aug 4. doi: 10.1007/s11033-023-08692-y. Online ahead of print.ABSTRACTCurrently, there are no truly effective treatments for a variety of eye diseases, such as glaucoma, age-related macular degeneration (AMD), and inherited retinal degenerations (IRDs). These conditions have a significant impact on patients' quality of life and can be a burden on society. However, these diseases share a common pathological process of NAD+ metabolism disorders. They are either associated with genetically induced primary NAD+ synthase deficiency, decreased NAD+ levels due to aging, or enhanced NAD+ consuming enzyme activit...
Source: Molecular Biology Reports - August 4, 2023 Category: Molecular Biology Authors: Siyuan Liu Wenfang Zhang Source Type: research
The efficient induction of human retinal ganglion-like cells provides a platform for studying optic neuropathies
Cell Mol Life Sci. 2023 Aug 4;80(8):239. doi: 10.1007/s00018-023-04890-w.ABSTRACTRetinal ganglion cells (RGCs) are essential for vision perception. In glaucoma and other optic neuropathies, RGCs and their optic axons undergo degenerative change and cell death; this can result in irreversible vision loss. Here we developed a rapid protocol for directly inducing RGC differentiation from human induced pluripotent stem cells (hiPSCs) by the overexpression of ATOH7, BRN3B, and SOX4. The hiPSC-derived RGC-like cells (iRGCs) show robust expression of various RGC-specific markers by whole transcriptome profiling. A functional asse...
Source: Cellular and Molecular Life Sciences : CMLS - August 4, 2023 Category: Cytology Authors: Roxanne Hsiang-Chi Liou Shih-Wei Chen Hui-Chen Cheng Pei-Chun Wu Yu-Fen Chang An-Guor Wang Ming-Ji Fann Yu-Hui Wong Source Type: research
