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Unilateral acute iris transillumination syndrome with glaucoma and iris pigment epithelium dispersion simulating iris melanoma
CONCLUSION AND IMPORTANCE: Unilateral acute iris transillumination syndrome with diffuse iris pigment epithelial loss can simulate iris melanoma. Prompt herpes viral studies may be informative.PMID:37680309 | PMC:PMC10481171 | DOI:10.1016/j.ajoc.2023.101912
Source: Herpes - September 8, 2023 Category: Infectious Diseases Authors: Orlando G Gonzalez Martinez Carol L Shields Jerry A Shields Patricia Ch évez-Barrios Debbie Rigney Walley Ralph C Eagle Tatyana Milman Source Type: research
Comparison of In Vitro Corneal Permeation and In Vivo Ocular Bioavailability in Rabbits of Three Marketed Latanoprost Formulations
ConclusionBAK did not influence the corneal penetration of latanoprost inin vitro andin vivo studies. The formulation containing a non-ionic surfactant resulted in lower and slower ocular penetration compared with preserved or PF SF formulations. This raises questions about the relevance of BAK and some surfactants in enhancing corneal penetration of ocular formulations.
Source: European Journal of Drug Metabolism and Pharmacokinetics - September 8, 2023 Category: Drugs & Pharmacology Source Type: research
Calcium Channel Blockers Again Linked to Glaucoma
(MedPage Today) -- Patients on calcium channel blockers (CCBs) had a higher likelihood of glaucoma than their counterparts, according to a population-based, cross-sectional study.
Examining data on more than 400,000 participants in the U.K. Biobank...
Source: MedPage Today Cardiovascular - September 7, 2023 Category: Cardiology Source Type: news
Chromatic Pupillometry - a New Technique for Assessing Function in Glaucoma?
Klin Monbl Augenheilkd. 2023 Sep 7. doi: 10.1055/a-2130-0546. Online ahead of print.ABSTRACTChromatic pupillometry allows quantification of photoreceptor-driven (extrinsic) and melanopsin-driven (intrinsic) responses of the intrinsic-photosensitive retinal ganglion cells (ipRGCs). This small subpopulation of retinal ganglion cells is also affected by glaucoma, making chromatic pupillometry a potential diagnostic tool. Studies show reduced phasic and tonic responses in glaucoma patients. The diagnostic value in earlier studies depended on the technical details and the study design. The purpose of this article is to give an ...
Source: Klinische Monatsblatter fur Augenheilkunde - September 7, 2023 Category: Opthalmology Authors: Cord Huchzermeyer Source Type: research
Acute angle closure glaucoma misdiagnosed as sinusitis
Pract Neurol. 2023 Sep 7:pn-2023-003864. doi: 10.1136/pn-2023-003864. Online ahead of print.ABSTRACTA 69-year-old woman developed severe right suprabulbar pain with blurred right-sided vision. There were no haloes around lights, photophobia, nausea or vomiting. Investigations in the emergency department excluded a posterior communicating/internal carotid artery aneurysm. However, she did not have an ophthalmological assessment and the initial diagnosis was of sinusitis-related headache. An urgent ear, nose and throat assessment found no abnormality, but a local ophthalmologist subsequently diagnosed and managed the patient...
Source: Practical Neurology - September 7, 2023 Category: Neurology Authors: Natalie Si-Yi Lee Thomas L Woo Ashish Agar Ian C Francis Source Type: research
Application of IPSC and M üller glia derivatives in retinal degenerative diseases
Prog Mol Biol Transl Sci. 2023;199:351-362. doi: 10.1016/bs.pmbts.2023.03.026. Epub 2023 Apr 27.ABSTRACTRetinal degenerative diseases cause blindness characterized by a progressive decline in the number and function of retinal pigment epithelium (RPE), photoreceptor cells, and ganglion cells. Such diseases include retinitis pigmentosa (RP), glaucomatous optic neuropathy, age-related macular degeneration and diabetic optic neuropathy. Recent studies have demonstrated that Müller glial cells (MGCs), an endogenous alternative source of retinal neurons, are important glial cells involved in retinal development, damage, and re...
Source: Mol Biol Cell - September 7, 2023 Category: Molecular Biology Authors: Guoge Han Pinghui Wei Quanhong Han Source Type: research
Chromatic Pupillometry - a New Technique for Assessing Function in Glaucoma?
Klin Monbl Augenheilkd. 2023 Sep 7. doi: 10.1055/a-2130-0546. Online ahead of print.ABSTRACTChromatic pupillometry allows quantification of photoreceptor-driven (extrinsic) and melanopsin-driven (intrinsic) responses of the intrinsic-photosensitive retinal ganglion cells (ipRGCs). This small subpopulation of retinal ganglion cells is also affected by glaucoma, making chromatic pupillometry a potential diagnostic tool. Studies show reduced phasic and tonic responses in glaucoma patients. The diagnostic value in earlier studies depended on the technical details and the study design. The purpose of this article is to give an ...
Source: Klinische Monatsblatter fur Augenheilkunde - September 7, 2023 Category: Opthalmology Authors: Cord Huchzermeyer Source Type: research
COMfort Eye Trial (COMET) results - a non-inferiority, randomized, investigator-masked, two-parallel group, phase III clinical trial, to evaluate the efficacy and safety of a preservative free formulation of latanoprost versus a reference drug (Xalatan ®) in patients with primary open-angle glaucoma (POAG) or ocular hypertension (OHT)
CONCLUSIONS: YSLT eye drops demonstrated non-inferiority to latanoprost in reducing IOP. Both products were well tolerated without serious TEAEs reported.PMID:37674345 | DOI:10.1080/14740338.2023.2252341
Source: Expert Opinion on Drug Safety - September 7, 2023 Category: Drugs & Pharmacology Authors: Stylianos Kandarakis Alexandros P Papadopoulos Georgios Roussopoulos Eustathios Georgopoulos Youngsik Chung Leonidas Doumazos Areum Baek Nefeli Ioanna Paizi Hyunik Shin Pantelis A Papadopoulos Source Type: research
Surgical outcomes of unwrapped acrylic orbital implants: A review of 192 patients
CONCLUSIONS: The stability and functional outcomes of unwrapped acrylic orbital implants in this group of patients were satisfactory during the follow-up period.PMID:37679221 | DOI:10.1016/j.jfo.2023.03.021
Source: Journal Francais d Ophtalmologie - September 7, 2023 Category: Opthalmology Authors: W Mularska M Wr óblewska-Zierhoffer W Adamski I Rospond-Kubiak Source Type: research
COMfort Eye Trial (COMET) results - a non-inferiority, randomized, investigator-masked, two-parallel group, phase III clinical trial, to evaluate the efficacy and safety of a preservative free formulation of latanoprost versus a reference drug (Xalatan ®) in patients with primary open-angle glaucoma (POAG) or ocular hypertension (OHT)
CONCLUSIONS: YSLT eye drops demonstrated non-inferiority to latanoprost in reducing IOP. Both products were well tolerated without serious TEAEs reported.PMID:37674345 | DOI:10.1080/14740338.2023.2252341
Source: Expert Opinion on Drug Safety - September 7, 2023 Category: Drugs & Pharmacology Authors: Stylianos Kandarakis Alexandros P Papadopoulos Georgios Roussopoulos Eustathios Georgopoulos Youngsik Chung Leonidas Doumazos Areum Baek Nefeli Ioanna Paizi Hyunik Shin Pantelis A Papadopoulos Source Type: research
Surgical outcomes of unwrapped acrylic orbital implants: A review of 192 patients
CONCLUSIONS: The stability and functional outcomes of unwrapped acrylic orbital implants in this group of patients were satisfactory during the follow-up period.PMID:37679221 | DOI:10.1016/j.jfo.2023.03.021
Source: Journal Francais d Ophtalmologie - September 7, 2023 Category: Opthalmology Authors: W Mularska M Wr óblewska-Zierhoffer W Adamski I Rospond-Kubiak Source Type: research
Application of IPSC and M üller glia derivatives in retinal degenerative diseases
Prog Mol Biol Transl Sci. 2023;199:351-362. doi: 10.1016/bs.pmbts.2023.03.026. Epub 2023 Apr 27.ABSTRACTRetinal degenerative diseases cause blindness characterized by a progressive decline in the number and function of retinal pigment epithelium (RPE), photoreceptor cells, and ganglion cells. Such diseases include retinitis pigmentosa (RP), glaucomatous optic neuropathy, age-related macular degeneration and diabetic optic neuropathy. Recent studies have demonstrated that Müller glial cells (MGCs), an endogenous alternative source of retinal neurons, are important glial cells involved in retinal development, damage, and re...
Source: Mol Biol Cell - September 7, 2023 Category: Molecular Biology Authors: Guoge Han Pinghui Wei Quanhong Han Source Type: research
Acute angle closure glaucoma misdiagnosed as sinusitis
Pract Neurol. 2023 Sep 7:pn-2023-003864. doi: 10.1136/pn-2023-003864. Online ahead of print.ABSTRACTA 69-year-old woman developed severe right suprabulbar pain with blurred right-sided vision. There were no haloes around lights, photophobia, nausea or vomiting. Investigations in the emergency department excluded a posterior communicating/internal carotid artery aneurysm. However, she did not have an ophthalmological assessment and the initial diagnosis was of sinusitis-related headache. An urgent ear, nose and throat assessment found no abnormality, but a local ophthalmologist subsequently diagnosed and managed the patient...
Source: Practical Neurology - September 7, 2023 Category: Neurology Authors: Natalie Si-Yi Lee Thomas L Woo Ashish Agar Ian C Francis Source Type: research
Chromatic Pupillometry - a New Technique for Assessing Function in Glaucoma?
Klin Monbl Augenheilkd. 2023 Sep 7. doi: 10.1055/a-2130-0546. Online ahead of print.ABSTRACTChromatic pupillometry allows quantification of photoreceptor-driven (extrinsic) and melanopsin-driven (intrinsic) responses of the intrinsic-photosensitive retinal ganglion cells (ipRGCs). This small subpopulation of retinal ganglion cells is also affected by glaucoma, making chromatic pupillometry a potential diagnostic tool. Studies show reduced phasic and tonic responses in glaucoma patients. The diagnostic value in earlier studies depended on the technical details and the study design. The purpose of this article is to give an ...
Source: Klinische Monatsblatter fur Augenheilkunde - September 7, 2023 Category: Opthalmology Authors: Cord Huchzermeyer Source Type: research
