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Total 26176 results found since Jan 2013.
Ocular findings in patients with acquired ATTRv amyloidosis following domino liver transplantation
ConclusionWhile cases of choroidal amyloid angiopathy were observed, serious amyloidosis-related ocular complications such as vitreous opacity or secondary glaucoma did not occur even in the long term after domino liver transplantation.
Source: PLoS One - September 15, 2023 Category: Biomedical Science Authors: Junya Kitahara Source Type: research
Biomaterials for Glaucoma Surgery
AbstractPurpose of ReviewHigh rates of fibrosis and bleb failure after conventional glaucoma surgeries have stimulated a renewed interest in developing biomaterials for glaucoma surgery. We review the latest findings on a variety of materials used to modify trabeculectomy, glaucoma drainage devices, nonpenetrating glaucoma surgeries and microinvasive glaucoma surgeries (MIGS).Recent FindingsWhile traditional implant materials like silicone and polypropylene can be inflammatory and lead to device encapsulation, new biomaterials are aimed at lessening postoperative inflammation and fibrosis. Natural polymers found in the eye...
Source: Current Ophthalmology Reports - September 15, 2023 Category: Opthalmology Source Type: research
Identification and Analysis of Primary Cilia in the Corneal Endothelial Cells of Patients with Bullous Keratopathy
CONCLUSION: The findings in this study clearly demonstrate the expression of primary cilia in the CECs of patients afflicted with BK.PMID:37706487 | DOI:10.1080/02713683.2023.2259633
Source: Current Eye Research - September 14, 2023 Category: Opthalmology Authors: Hideto Deguchi Hidetoshi Tanioka Mako Watanabe Noriko Horiuchi Hideki Fukuoka Osamu Hieda Tsutomu Inatomi Shigeru Kinoshita Chie Sotozono Source Type: research
Factors Associated with Topical Medication Instillation Failure in Glaucoma: VRAMS-QPiG Study
CONCLUSION: In addition to older age, decreased cognitive function, hyperopia, and decreased foveal sensitivity are risks for failed eyedrop instillation. Treating physicians can screen patients who require guidance by checking the risk factors of instillation failure rather than by relying on patient reports.PMID:37707675 | DOI:10.1007/s12325-023-02646-3
Source: Adv Data - September 14, 2023 Category: Epidemiology Authors: Masaki Tanito Mihoko Mochiji Aika Tsutsui Akiko Harano Sho Ichioka Yuji Takayanagi Yumiko Kataoka Yasutaka Takagi Daisuke Shii Source Type: research
Identification and Analysis of Primary Cilia in the Corneal Endothelial Cells of Patients with Bullous Keratopathy
CONCLUSION: The findings in this study clearly demonstrate the expression of primary cilia in the CECs of patients afflicted with BK.PMID:37706487 | DOI:10.1080/02713683.2023.2259633
Source: Current Eye Research - September 14, 2023 Category: Opthalmology Authors: Hideto Deguchi Hidetoshi Tanioka Mako Watanabe Noriko Horiuchi Hideki Fukuoka Osamu Hieda Tsutomu Inatomi Shigeru Kinoshita Chie Sotozono Source Type: research
Anterior segment complications after dexamethasone implantations:real world data
ConclusionThis study is the first long-term follow-up study in our country evaluating the safety of dexamethasone implant injections in various retinal diseases and presenting the first real world data. Cataract progression and increased IOP were found to be the most common side effects. We observed that the patient ’s diagnosis did not cause a statistically significant change in the observation of side effects. As a result of our findings, close follow-up of IOP after the injection of dexamethasone implants would be appropriate.
Source: International Ophthalmology - September 14, 2023 Category: Opthalmology Source Type: research
Impact of primary glaucoma on health-related quality of life in China: the handan eye study
We assessed health-related quality of life (HRQOL) and its determinants among rural glaucoma participants compared to age-matched normal controls in the population-based Handan Eye Study (HES), in rural Yongni...
Source: BMC Ophthalmology - September 14, 2023 Category: Opthalmology Authors: Di Song, Sujie Fan, Qiang Zhou, Xiaohui Yang, Sizhen Li, Lynne Lohfeld, Weihe Zhou, Nathan Congdon, Yuanbo Liang and Ningli Wang Tags: Research Source Type: research
Phase 3 Clinical Trial Comparing the Safety and Efficacy of Netarsudil to Ripasudil in Patients with Primary Open-Angle Glaucoma or Ocular Hypertension: Japan Rho Kinase Elevated Intraocular Pressure Treatment Trial (J-ROCKET)
ConclusionNetarsudil ophthalmic solution 0.02% dosed QD (p.m.) was well tolerated and more effective in reducing IOP than ripasudil ophthalmic solution 0.4% dosed BID. Netarsudil 0.02% QD may become an important option for the treatment of Japanese patients with primary open-angle glaucoma (POAG) or ocular hypertension (OHT).Trial registrationClinicalTrials.gov identifier, NCT04620135.
Source: Advances in Therapy - September 13, 2023 Category: Drugs & Pharmacology Source Type: research
Potential of mesenchymal stem cell-derived conditioned medium/secretome as a therapeutic option for ocular diseases
Regen Med. 2023 Sep 13. doi: 10.2217/rme-2023-0089. Online ahead of print.ABSTRACTResearch has shown that the therapeutic effect of mesenchymal stem cells (MSCs) is partially due to its secreted factors as opposed to the implantation of the cells into the treated tissue or tissue replacement. MSC secretome, especially in the form of conditioned medium (MSC-CM) is now being explored as an alternative to MSCs transplantation. Despite the observed benefits of MSC-CM, only a few clinical trials have evaluated it and other secretome components in the treatment of eye diseases. This review provides insight into the potential the...
Source: Regenerative Medicine - September 13, 2023 Category: Genetics & Stem Cells Authors: Wesley Harrisson Bouche Djatche Huimin Zhu Wenlei Ma Yue Li Ziang Li Hong Zhao Zhizhen Liu Hua Qiao Source Type: research
