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Total 26176 results found since Jan 2013.
Potential of mesenchymal stem cell-derived conditioned medium/secretome as a therapeutic option for ocular diseases
Regen Med. 2023 Sep 13. doi: 10.2217/rme-2023-0089. Online ahead of print.ABSTRACTResearch has shown that the therapeutic effect of mesenchymal stem cells (MSCs) is partially due to its secreted factors as opposed to the implantation of the cells into the treated tissue or tissue replacement. MSC secretome, especially in the form of conditioned medium (MSC-CM) is now being explored as an alternative to MSCs transplantation. Despite the observed benefits of MSC-CM, only a few clinical trials have evaluated it and other secretome components in the treatment of eye diseases. This review provides insight into the potential the...
Source: Regenerative Medicine - September 13, 2023 Category: Genetics & Stem Cells Authors: Wesley Harrisson Bouche Djatche Huimin Zhu Wenlei Ma Yue Li Ziang Li Hong Zhao Zhizhen Liu Hua Qiao Source Type: research
Coexistence of open-angle glaucoma and sarcoidosis-associated optic neuropathy
We present a case of preexisting open-angle glaucoma and concurrent invol...
Source: BMC Ophthalmology - September 13, 2023 Category: Opthalmology Authors: Eun Hye Jung, Woonghee Kim, Ra Gyoung Yoon and Ko Eun Kim Tags: Case Report Source Type: research
Half of Older Adults With Glaucoma Unaware They Have It
TUESDAY, Sept. 12, 2023 -- Many older adults with glaucoma may be undiagnosed, according to a study published online July 17 in Acta Ophthalmologica.
Lena Havstam Johansson, from the University of Gothenburg in Sweden, and colleagues estimated the...
Source: Drugs.com - Pharma News - September 12, 2023 Category: Pharmaceuticals Source Type: news
GSE213217 High concentration of adrenaline blocks key cell cycle genes and exhibits antifibrotic and vasoconstrictor effects in glaucoma surgery
Contributor : Cynthia Yu-Wai-ManSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTo investigate the effects of adrenaline on fibrosis in glaucoma surgery. Human Tenon ’s fibroblasts (HTFs) were treated with adrenaline (0%, 0.0005%, 0.01%) for 24 hours and RNA-Sequencing was performed on the Illumina NextSeq2000. We carried out detailed gene ontology, pathway, disease and drug enrichment analyses.
Source: GEO: Gene Expression Omnibus - September 12, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
Intravitreal fluocinolone acetonide 0.19 mg (ILUVIEN®) in patients with non-infectious uveitis: real-world effectiveness and safety outcomes at 12 months
ConclusionThe FAc implant is safe and effective at treating NIU over 12 months in a real-world setting in Spain.
Source: International Ophthalmology - September 12, 2023 Category: Opthalmology Source Type: research
Novel Quinazolinone Derivatives: Synthetic Analogues for the Treatment of Glaucoma, Alzheimer's Disease and Diabetes Mellitus
Chem Biodivers. 2023 Sep 11:e202301134. doi: 10.1002/cbdv.202301134. Online ahead of print.ABSTRACTNovel quinazolinone derivatives (1-21) were synthesized from the reaction of acylated derivatives of 4-hydroxy benzaldehyde (AAD) with 3-amino-2-alkylquinazolin-4(3H)-ones (QD) with good yields (85-94%). The structures of the novel molecules were characterized using Fourier-transform Infrared (FTIR), Nuclear Magnetic Resonance (1H NMR - 13C NMR), and High-Resolution Mass Spectroscopy (HRMS). As the application of the synthesized compounds, their inhibition properties of the synthesized compounds on α-Glucosidase (α-Glu), Ac...
Source: Chemistry and Biodiversity - September 11, 2023 Category: Biochemistry Authors: Feyzi Sinan Tokal ı Parham Taslimi Burak Tuzun Ahmet Karaku ş Nastaran Sadeghian İlhami Gulçin Source Type: research
Association between helicobacter pylori infection and primary open-angle glaucoma: a systematic review and meta-analysis
This systematic review and meta-analysis summarize the evidence for the association between Helicobacter pylori infection and Primary Open-Angle Glaucoma.
Source: BMC Ophthalmology - September 11, 2023 Category: Opthalmology Authors: Elnaz Ezzati Amini and Yousef Moradi Tags: Research Source Type: research
Assessment of the iridocorneal angle pigmentation and structures after the implantation of EVO+ Visian Implantable Collamer Lens
ConclusionsThe EVO+ ICL implantation after uneventful procedures appears not to clinically affect the iridocorneal angle pigmentation and/or structures during a short-medium follow-up using gonioscopy assessment. The intra-rater reliability of glaucoma specialists assessing iridocorneal angle structures using gonios copy images is very high.
Source: International Ophthalmology - September 11, 2023 Category: Opthalmology Source Type: research
Utility of targeted mean total deviation trend analysis for detecting progressive visual field changes in early-to-moderate stage glaucoma
Eye, Published online: 11 September 2023; doi:10.1038/s41433-023-02726-2Utility of targeted mean total deviation trend analysis for detecting progressive visual field changes in early-to-moderate stage glaucoma
Source: Eye - September 11, 2023 Category: Opthalmology Authors: Woo Keun Song Ko Eun Kim Anna Lee Jooyoung Yoon Michael S. Kook Source Type: research
Adverse Association Identified for Calcium Channel Blocker Use, Glaucoma
FRIDAY, Sept. 8, 2023 -- There is an adverse association between calcium channel blocker (CCB) use and glaucoma, according to a study published online Sept. 7 in JAMA Ophthalmology.
Alan Kastner, M.D., from Moorfields Eye Hospital National Health...
Source: Drugs.com - Pharma News - September 8, 2023 Category: Pharmaceuticals Source Type: news
Older people may have common eye condition that causes blindness without realising - study
In new research, half of those diagnosed with glaucoma were unaware of having it.
Source: Daily Express - Health - September 8, 2023 Category: Consumer Health News Source Type: news
Some With Glaucoma May Not Even Know They Have It
FRIDAY, Sept. 8, 2023 -- New Swedish research suggests that up to 5% of 70-year-olds have glaucoma, and half of those diagnosed didn ' t even know they had the disease. “Of those who were diagnosed with glaucoma via the study, 15 people -- or 2.7%...
Source: Drugs.com - Daily MedNews - September 8, 2023 Category: General Medicine Source Type: news
Unilateral acute iris transillumination syndrome with glaucoma and iris pigment epithelium dispersion simulating iris melanoma
CONCLUSION AND IMPORTANCE: Unilateral acute iris transillumination syndrome with diffuse iris pigment epithelial loss can simulate iris melanoma. Prompt herpes viral studies may be informative.PMID:37680309 | PMC:PMC10481171 | DOI:10.1016/j.ajoc.2023.101912
Source: Herpes - September 8, 2023 Category: Infectious Diseases Authors: Orlando G Gonzalez Martinez Carol L Shields Jerry A Shields Patricia Ch évez-Barrios Debbie Rigney Walley Ralph C Eagle Tatyana Milman Source Type: research
