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Primary Yolk Sac Tumor of the Prostate: A Case Report and Review of the Literature
We report a case of prostatic EST, the first case in which the patient had a history of previous testis cancer. Treatment included cisplatin-based chemotherapy and radical prostatectomy. Previous cases of primary ESTs and use of cisplatin-based therapy as well as metastatic tumors to the prostate are discussed.Urol Int
Source: Urologia Internationalis - April 1, 2015 Category: Urology & Nephrology Source Type: research
Direct Effects of Microalgae and Protists on Herring (Clupea harengus) Yolk Sac Larvae
This study investigated effects of microalgae (Rhodomonas baltica) and heterotrophic protists (Oxyrrhis marina) on the daily growth, activity, condition and feeding success of Atlantic herring (Clupea harengus) larvae from hatch, through the end of the endogenous (yolk sac) period. Yolk sac larvae were reared in the presence and absence of microplankton and, each day, groups of larvae were provided access to copepods. Larvae reared with microalgae and protists exhibited precocious (2 days earlier) and ≥ 60% increased feeding incidence on copepods compared to larvae reared in only seawater (SW). In the absence and presenc...
Source: PLoS One - June 2, 2015 Category: Biomedical Science Authors: Björn Illing et al. Source Type: research
Vaginal Yolk Sac Tumor in an Infant: A Case Report and Literature Review of the Last 30 Years
Vaginal yolk sac tumor is a rare malignant germ-cell tumor occurring most commonly in young girls. The treatment has evolved over the last 3 decades from radical surgery to conservative surgery with chemotherapy to chemotherapy alone. Here we present a case of a 6-month-old girl successfully treated with upfront surgery followed by chemotherapy. We include a literature review of studies on vaginal yolk sac tumor published in the last 30 years. We discuss the role of upfront surgery where possible followed by chemotherapy as a safe alternative to chemotherapy alone for the treatment of this rare malignancy.
Source: Journal of Pediatric Hematology Oncology - June 25, 2015 Category: Hematology Tags: Online Articles: Clinical and Laboratory Observations Source Type: research
Accuracy of first‐trimester ultrasound in diagnosis of intrauterine pregnancy prior to visualization of the yolk sac: a systematic review and meta‐analysis
ConclusionVisualization of a gestational sac, double decidual sac sign, intradecidual sign or chorionic rim sign increases the probability of an intrauterine pregnancy but is not as accurate for diagnosis as the detection of the yolk sac. However, the findings were limited by the small number and poor quality of the studies included and heterogeneity in the index test and reference standard. Copyright © 2014 ISUOG. Published by John Wiley & Sons Ltd.
Source: Ultrasound in Obstetrics and Gynecology - June 29, 2015 Category: Radiology Authors: A. Richardson, I. Gallos, S. Dobson, B. K. Campbell, A. Coomarasamy, N. Raine‐Fenning Tags: Systematic Review Source Type: research
Definitive Hematopoiesis In The Yolk Sac Emerges from Wnt‐responsive Hemogenic Endothelium Independently Of Circulation and Arterial Identity
This article is protected by copyright. All rights reserved.
Graphical Abstract
Definitive hematopoiesis initiates as a broad temporal wave of yolk sac‐derived erythro‐myeloid progenitor (EMP) colony‐forming potential (red arrow with shaded area). EMPs emerge from flattened hemogenic endothelium (HE; green dotted line) between embryonic day (E)8.5 through as late as E10.5‐11, which correlates with the known temporal requirement for Runx1 in mediating EMP formation (green trapezoid). EMPs emerge from both arterial and venous regions of the yolk sac and do not require blood flow, but are regulated by Wnt signaling. ...
Source: Stem Cells - September 30, 2015 Category: Stem Cells Authors: Jenna M. Frame, Katherine H. Fegan, Simon J. Conway, Kathleen E. McGrath, James Palis Tags: Tissue‐Specific Stem Cells Source Type: research
Transdifferentiation of mouse visceral yolk sac cells into parietal yolk sac cells in vitro.
Abstract
The mouse embryonic yolk sac is an extraembryonic membrane that consists of a visceral yolk sac (VYS) and parietal yolk sac (PYS), and functions in hematopoietic-circulation in the fetal stage. The present study was undertaken to examine the normal development of both murine VYS and PYS tissues using various molecular markers, and to establish a novel VYS cell culture system in vitro for analyzing differentiation potentials of VYS cells. RT-PCR and immunohistochemical analyses of gene expression in VYS and PYS tissues during development revealed several useful markers for their identification: HNF1β, HNF...
Source: Biochemical and Biophysical Research communications - January 25, 2016 Category: Biochemistry Authors: Yagi S, Tagawa YI, Shiojiri N Tags: Biochem Biophys Res Commun Source Type: research
Ovarian Yolk Sac Tumor: The Experience of a Regional Cancer Center
Conclusions: Postsurgery satisfactory AFP decline was an independent significant prognostic factor for patient survival. Omentectomy might not be of therapeutic significance for clinical stage I-II patients.
Source: International Journal of Gynecological Cancer - May 24, 2016 Category: Cancer & Oncology Tags: Ovarian Cancer Source Type: research
Pure Yolk sac presenting with inferior vena cava thrombus extending from bilateral external iliac veins to hepatic vein
Conclusion: We review this seldom case and discuss the literature with regard to its diagnosis and treatment.
Source: International Braz J Urol - November 25, 2016 Category: Urology & Nephrology Source Type: research
Different mechanisms of Na+ uptake and ammonia excretion by the gill and yolk sac epithelium of early life stage rainbow trout RESEARCH ARTICLE
Alex M. Zimmer, Jonathan M. Wilson, Patricia A. Wright, Junya Hiroi, and Chris M. Wood In rainbow trout, the dominant site of Na+ uptake (JNain) and ammonia excretion (Jamm) shifts from the skin to the gills over development. Post-hatch (PH; 7 days post-hatch) larvae utilize the yolk sac skin for physiological exchange, whereas by complete yolk sac absorption (CYA; 30 days post-hatch), the gill is the dominant site. At the gills, JNain and Jamm occur via loose Na+/NH4+ exchange, but this exchange has not been examined in the skin of larval trout. Based on previous work, we hypothesized that, contrary to the gill model, JNa...
Source: Journal of Experimental Biology - December 12, 2016 Category: Biology Authors: Zimmer, A. M., Wilson, J. M., Wright, P. A., Hiroi, J., Wood, C. M. Tags: RESEARCH ARTICLE Source Type: research
Chemotherapy for primary mediastinal yolk sac tumor in a patient undergoing chronic hemodialysis: a case report
ConclusionsBecause of the altered pharmacokinetics pharmacodynamics status of patients with renal dysfunction undergoing hemodialysis, pharmacokinetics pharmacodynamics analysis is deemed to be helpful for effective and safe management of chemotherapy in patients undergoing hemodialysis.
Source: Journal of Medical Case Reports - February 15, 2017 Category: Journals (General) Source Type: research
Different mechanisms of Na+ uptake and ammonia excretion by the gill and yolk sac epithelium of early life stage rainbow trout RESEARCH ARTICLE
Alex M. Zimmer, Jonathan M. Wilson, Patricia A. Wright, Junya Hiroi, and Chris M. Wood
In rainbow trout, the dominant site of Na+ uptake (JNa,in) and ammonia excretion (Jamm) shifts from the skin to the gills over development. Post-hatch (PH; 7 days post-hatch) larvae utilize the yolk sac skin for physiological exchange, whereas by complete yolk sac absorption (CYA; 30 days post-hatch), the gill is the dominant site. At the gills, JNa,in and Jamm occur via loose Na+/NH4+ exchange, but this exchange has not been examined in the skin of larval trout. Based on previous work, we hypothesized that, contrary to the gi...
Source: Journal of Experimental Biology - February 28, 2017 Category: Biology Authors: Zimmer, A. M., Wilson, J. M., Wright, P. A., Hiroi, J., Wood, C. M. Tags: RESEARCH ARTICLE Source Type: research
ZBTB16 is a sensitive and specific marker in detection of metastatic and extragonadal yolk sac tumor
ConclusionZBTB16 is a sensitive and specific marker for YST and is diagnostically superior to AFP and Glypican‐3 in metastatic and extragonadal settings.This article is protected by copyright. All rights reserved.
Source: Histopathology - June 1, 2017 Category: Pathology Authors: Guang ‐Qian Xiao, David S. Priemer, Christina Wei, Manju Aron, Qi Yang, Muhammad T. Idrees Tags: Original Article Source Type: research
Embryo yolk sac membrane kynurenine formamidase of l-tryptophan to NAD(+) pathway as a primary target for organophosphorus insecticides (OPI) in OPI-induced NAD-associated avian teratogenesis.
The objective of this study was to provide in ovo evidence for the proposed role of kynurenine formamidase of l-tryptophan to NAD(+) pathway in embryo yolk sac membranes as a primary target for organophosphorus insecticide (OPI) teratogens in OPI-induced NAD-associated avian teratogenesis. Slices prepared from yolk sac membranes or embryo livers of chicken eggs treated with the OPI dicrotophos and/or methyl parathion were incubated with l-tryptophan. Yolk sac membrane slices metabolized l-tryptophan in the pathway to NAD(+) before that function was established in livers. OPI interfered in ovo with the second step of l-tryp...
Source: Toxicology in Vitro - August 4, 2017 Category: Toxicology Authors: Seifert J Tags: Toxicol In Vitro Source Type: research
Management and prognosis of ovarian yolk sac tumors; an analysis of the National Cancer Data Base.
CONCLUSIONS: Women with OYST commonly present with early stage disease. Administration of adjuvant chemotherapy, early stage and younger age are associated with superior outcomes.
PMID: 28803748 [PubMed - as supplied by publisher]
Source: Gynecologic Oncology - August 10, 2017 Category: Cancer & Oncology Authors: Nasioudis D, Chapman-Davis E, Frey MK, Caputo TA, Holcomb K Tags: Gynecol Oncol Source Type: research
A histopathological connection between a fatal endolymphatic sac tumour and von Hippel-Lindau disease from 1960.
CONCLUSION: Endolymphatic sac tumours are rare neoplasms of the temporal bone that can occur sporadically or as part of von Hippel-Lindau disease. The connection between endolymphatic sac tumour and von Hippel-Lindau disease was first proposed in 1988 and formalised in 1997. We believe that this case represents the first documented connection between endolymphatic sac tumour and von Hippel-Lindau disease.
PMID: 28874214 [PubMed - as supplied by publisher]
Source: Journal of Laryngology and Otology - September 8, 2017 Category: ENT & OMF Tags: J Laryngol Otol Source Type: research
