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Total 478012 results found since Jan 2013.
Validating a software for the automatic detection of aortic aneurysms
The objective of this study was to evaluate and validate a new software for automated detection, follow-up, and decision support in patients with aortic aneurysms.
Source: Annals of Vascular Surgery - September 20, 2023 Category: Surgery Authors: Aude Gatinot, Soumia Sebaihi, Lamia Stephan, Florian Bernard, Simon Rinckenbach, Lucie Salomon Du Mont Source Type: research
Radiation protection training by Monte Carlo Simulation and virtual reality
The objective of this study was to combine VR and Monte Carlo (MC) simulation-based dosimetry in radiation protection education.
Source: Annals of Vascular Surgery - September 20, 2023 Category: Surgery Authors: Bahaa Nasr, Barbara Guyomard, Dimitris Visvikis, Julien Bert Source Type: research
The implication of viability and pathogenicity by truncated lipopolysaccharide in Yersinia enterocolitica
In this study, truncated LPS caused by waaF deletion was used as a model of envelope stress in Y. enterocolitica. We investigated the mechanisms of envelope stress responses and the cellular functions affected by truncated LPS. Transcriptome analysis and phenotypic validation showed that LPS truncation reduced flagellar assembly, bacterial chemotaxis, and inositol phosphate metabolism, presenting lower pathogenicity and viability both in vivo and in vitro environments. Further 4D label-free phosphorylation analysis confirmed that truncated LPS perturbed multiple intracellular signal transduction pathways. Specifically, a c...
Source: Applied Microbiology and Biotechnology - September 20, 2023 Category: Microbiology Authors: Fan Wu Fengyun Ren Xixian Xie Jiao Meng Xin Wu Source Type: research
Impact of tidal volume strategy at birth on initiating lung injury in preterm lambs
Am J Physiol Lung Cell Mol Physiol. 2023 Sep 20. doi: 10.1152/ajplung.00159.2023. Online ahead of print.ABSTRACTTidal ventilation is essential in supporting the transition to air-breathing at birth, but excessive tidal volume (VT) is an important factor in preterm lung injury. Few studies have assessed the impact of specific VT levels on injury development. Here we used a lamb model of preterm birth to investigate the role of different levels of VT during positive pressure ventilation (PPV) in promoting aeration and initiating early lung injury pathways. VT was delivered as; (i) 7ml/kg throughout (VTstatic), (ii) begun at ...
Source: Am J Physiol Lung Ce... - September 20, 2023 Category: Respiratory Medicine Authors: Prue M Pereira-Fantini Kelly R Kenna Monique Fatmous Arun Sett Ellen Douglas Sophia Dahm Magdy Sourial Haoyun Fang David W Greening David G Tingay Source Type: research
Essential Competencies in Entry-Level Neurologic Physical Therapist Education: Erratum
J Neurol Phys Ther. 2023 Oct 1;47(4):216. doi: 10.1097/NPT.0000000000000460. Epub 2023 Aug 7.NO ABSTRACTPMID:37728440 | DOI:10.1097/NPT.0000000000000460
Source: Physical Therapy - September 20, 2023 Category: Physiotherapy Source Type: research
Peroxiredoxins in erythrocytes: far beyond the antioxidant role
J Mol Med (Berl). 2023 Sep 20. doi: 10.1007/s00109-023-02368-7. Online ahead of print.ABSTRACTThe red blood cells (RBCs) are essential to transport oxygen (O2) and nutrients throughout the human body. Changes in the structure or functioning of the erythrocytes can lead to several deficiencies, such as hemolytic anemias, in which an increase in reactive oxidative species generation is involved in the pathophysiological process, playing a significant role in the severity of several clinical manifestations. There are important lines of defense against the damage caused by oxidizing molecules. Among the antioxidant molecules, ...
Source: Molecular Medicine - September 20, 2023 Category: Molecular Biology Authors: Carla Peres de Paula Jo ão Pedro Maia de Oliveira da Silva Karen Simone Romanello Victoria Sim ões Bernardo Flaviene Felix Torres Danilo Gr ünig Humberto da Silva Anderson Ferreira da Cunha Source Type: research
A New Strategy for Rejuvenating Primary Healthcare: The Government-Society Partnership Model
J Prim Care Community Health. 2023 Jan-Dec;14:21501319231200763. doi: 10.1177/21501319231200763.ABSTRACTPrimary healthcare systems worldwide are under stress as increased demands during pandemic surges have exposed deficiencies in the system. Primary healthcare centers have significant responsibilities but are often underfunded and understaffed. Recent events, including the COVID-19 pandemic, have highlighted the importance of a strong primary health center network to promote community health and save lives. Most governments have multiple competing financial needs for scarce resources, ultimately limiting the advancement o...
Source: Primary Care - September 20, 2023 Category: Primary Care Authors: Siddarth S Kasi Source Type: research
Shuttle between arginine and lysine: influence on cancer immunonutrition
Amino Acids. 2023 Sep 20. doi: 10.1007/s00726-023-03327-9. Online ahead of print.ABSTRACTAmino acids which are essential nutrients for all cell types' survival are also recognised to serve as opportunistic/alternative fuels in cancers auxotrophic for specific amino acids. Accordingly, restriction of amino acids has been utilised as a therapeutic strategy in these cancers. Contrastingly, amino acid deficiencies in cancer are found to greatly impair immune functions, increasing mortality and morbidity rates. Dietary and supplemental amino acids in such conditions have revealed their importance as 'immunonutrients' by modulat...
Source: Amino Acids - September 20, 2023 Category: Biochemistry Authors: R Sindhu M Supreeth Shashanka K Prasad M Thanmaya Source Type: research
Unique Presentations of Burkholderia gladioli Infections in Several Strains of Immunocompromised Mice
Comp Med. 2023 Sep 20. doi: 10.30802/AALAS-CM-23-000016. Online ahead of print.ABSTRACTFour strains of experimentally naïve mice (NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ [NSG], NOD.Cg-Rag1tm1Mom Il2rgtm1Wjl/SzJ[NRG], B6.129S(Cg)-Stat1tm1Dlv/J [STAT1-/-], and B6.129S7-Ifngr1tm1Agt/J [IFNγR-/-] housed in a barrier facility developedunusual and seemingly unrelated clinical signs. Young NSG/NRG mice (n = 49, mean age = 4 ± 0.4 mo) exhibited nonspecificclinical signs of moderate-to-severe lethargy, hunched posture, decreased body condition, and pallor. In contrast to the NSG/NRGmice, the STAT1-/- and IFNγR-/-mice (n = 5) developed...
Source: Comparative Medicine - September 20, 2023 Category: Zoology Authors: Andrea J Osborne Sarah E Clark Tiffany L Whitcomb Penny L Devlin Matthew R Lanza Hannah M Atkins Source Type: research
Comprehensive profiling of the metabolome in corn silage inoculated with or without < em > Lactiplantibacillus plantarum < /em > using different untargeted metabolomics analyses
Arch Anim Nutr. 2023 Sep 19:1-19. doi: 10.1080/1745039X.2023.2247824. Online ahead of print.ABSTRACTSilage fermentation is a complicated biochemical process involving interactions between microbes and metabolites. However, the overall metabolome feature of ensiled forage and its response to lactic acid bacteria inoculation is poorly understood. Hence, in this study metabolome profiles of whole-plant corn silage inoculated with or without Lactiplantibacillus plantarum were characterised via solid-phase microextraction/gas chromatography/mass spectrometry (SPME-GC-MS), gas chromatography/time-of-flight mass spectrometry (GC-...
Source: Archives of Animal Nutrition - September 20, 2023 Category: Nutrition Authors: Rina Su Wencan Ke Jie Bai Musen Wang Samaila Usman Dongmei Xie Dongmei Xu Mengyan Chen Xusheng Guo Source Type: research
Mineral elements and adiposity-related consequences in adolescents with intellectual disabilities
CONCLUSION: The intellectual disability of moderate type (MID) was associated with abnormal changes in the levels of essential mineral elements and adipokines and increased levels of cellular oxidative stress. Thus, evaluating plasma mineral elements and adipokines levels could be a potential diagnostic parameter for diagnosing MID.PMID:37730529 | DOI:10.1186/s12860-023-00490-5
Source: Mol Biol Cell - September 20, 2023 Category: Molecular Biology Authors: Ahmad H Alghadir Sami A Gabr Amir Iqbal Source Type: research
Effects of management objectives and rules on marine conservation outcomes
This article is protected by copyright. All rights reserved.PMID:37728514 | DOI:10.1111/cobi.14156
Source: Conservation Biology - September 20, 2023 Category: Biology Authors: Natalie C Ban Emily S Darling Georgina G Gurney Whitney Friedman Stacy D Jupiter W Peni Lestari Irfan Yulianto Sinta Pardede Sukma A R Tarigan Puji Prihatiningsih Sangeeta Mangubhai Waisea Naisilisili Sirilo Dulunaqio Josheena Naggea Ravaka Ranaivoson Ver Source Type: research
Assessment of the Alga < em > Cladophora glomerata < /em > as a Source for Cellulose Nanocrystals
Biomacromolecules. 2023 Sep 20. doi: 10.1021/acs.biomac.3c00380. Online ahead of print.ABSTRACTNanocellulose is isolated from cellulosic fibers and exhibits many properties that macroscale cellulose lacks. Cellulose nanocrystals (CNCs) are a subcategory of nanocellulose made of stiff, rodlike, and highly crystalline nanoparticles. Algae of the order Cladophorales are the source of the longest cellulosic nanocrystals, but manufacturing these CNCs is not well-studied. So far, most publications have focused on the applications of this material, with the basic manufacturing parameters and material properties receiving little a...
Source: Biomacromolecules - September 20, 2023 Category: Biochemistry Authors: Karl Mihhels Neptun Yousefi Jaanika Blomster Iina Solala Laleh Solhi Eero Kontturi Source Type: research
Whole-genome resequencing reveals new mutations in candidate genes for Beichuan-white goat prolificacya
In this study, we evaluated the copy number variation in the genomes of two groups of Beichuan-white goat populations with large differences in litter size by FST method, and identified 1739 genes and 485 missense mutations in the genes subject to positive selection. Through functional enrichment, ITGAV, LRP4, CDH23, TPRN, RYR2 and CELSR1 genes, involved in embryonic morphogenesis, were essential for litter size trait, which received intensive attention. In addition, some mutation sites of these genes have been proposed (ITGAV: c.38C > T; TPRN: c.133A > T, c.1192A > G, c.1250A > C; CELSR1: c.7640T > C), whos...
Source: Animal Biotechnology - September 20, 2023 Category: Biotechnology Authors: Aimin Zhou Yi Ding Xiaohui Zhang Yugang Zhou Yadong Liu Tingjian Li Long Xiao Source Type: research
Applications and Challenges of Bacteriostatic Aptamers in the Treatment of Common Pathogenic Bacteria Infections
Biomacromolecules. 2023 Sep 20. doi: 10.1021/acs.biomac.3c00634. Online ahead of print.ABSTRACTThe continuous evolution and spread of common pathogenic bacteria is a major challenge in diagnosis and treatment with current biotechnology and modern molecular medicine. To confront this challenge, scientists urgently need to find alternatives for traditional antimicrobial agents. Various bacteriostatic aptamers obtained through SELEX screening are one of the most promising strategies. These bacteriostatic aptamers can reduce bacterial infection by blocking bacterial toxin infiltration, inhibiting biofilm formation, preventing ...
Source: Biomacromolecules - September 20, 2023 Category: Biochemistry Authors: Diandian Li Yuan Su Jie Li Rong Liu Bing Fang Jingjing He Wentao Xu Longjiao Zhu Source Type: research
