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The Lack of Consensus on Approaches to Aging as a Flaw to be Fixed
It can be argued that the largest challenge facing the development of means to treat aging as a medical condition is that there is, as of yet, no useful consensus position on how to measure aging, how to define aging, or which of the countless measurable aspects of biochemistry that change with age are the most appropriate targets for therapy. This means that any given research group or biotech startup has a lot of leeway to argue that their approach is the right one - and it might take twenty years to establish the effects of their therapies on long-term health and life span, even given a successful development program. T...
Source: Fight Aging! - September 19, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Self-limiting thin film deposition of amorphous metal oxides from aprotic solvents for oxygen evolution electrocatalysis
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Rafael Prato, Jan Fransaer, Xochitl Dominguez-Benetton In the context of global energy and environmental challenges, developing efficient and sustainable methods for energy storage and conversion is essential. Amorphous thin films of nanoporous single and mixed Ni,... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - J. Mater. Chem. latest articles - September 19, 2023 Category: Chemistry Authors: Rafael Prato Source Type: research

Data-Driven Deep Generative Design of Stable Spintronic Materials
CrystEngComm, 2023, Accepted Manuscript DOI: 10.1039/D3CE00765K, PaperEdirisuriya Siriwardane, Yong Zhao, Jianjun Hu Discovering novel magnetic materials is essential for advancing the spintronic technology with significant applications in data communication, data storage, quantum computing, and etc. While Density functional theory (DFT) has been... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - CrystEngComm latest articles - September 19, 2023 Category: Chemistry Authors: Edirisuriya Siriwardane Source Type: research

Catalogues of EQ-5D-3L Health-Related Quality of Life Scores for 199 Chronic Conditions and Health Risks for Use in the UK and the USA
ConclusionsThis study provides comprehensive catalogues of UK/US EQ-5D-3L HRQoL utilities. Results are relevant in cost-effectiveness analysis, for NICE submissions, and for comparing and identifying facets of disease burden.
Source: PharmacoEconomics - September 19, 2023 Category: Health Management Source Type: research

The racialization of Latino families - Baca Zinn M, Wells B.
While racial and demographic changes producing a multiracial United States are well-acknowledged in the family field, insufficient attention is given to Latinos as a racialized population. As the Latino population continues to expand, it is essential for f...
Source: SafetyLit - September 19, 2023 Category: International Medicine & Public Health Tags: Jurisprudence, Laws, Legislation, Policies, Rules Source Type: news

Integrating spatial cost path and multi-criteria analysis for finding alternative routes during flooding - Rasam ARA, Taileh V, Lin S, Adnan NA, Ghazali R.
Route accessibility is essential infrastructure, facilitating more convenient transit for individuals. Nonetheless, the seasonal monsoon can lead to flooding and impair the accessibility of local transportation, especially in hilly-lowland areas. This stud...
Source: SafetyLit - September 19, 2023 Category: International Medicine & Public Health Tags: Disaster Preparedness Source Type: news

Educational agents and institutions called into action in suicide prevention, intervention, and postvention - de Oliveira JM, Due ñas JM, Morales-Vives F, Gallardo-Nieto E.
IntroductionSuicide is the second leading cause of death in the 15 to 29 age group worldwide, and is a severe public health problem. Adolescent and young adult individuals attend educational institutions which can play an essential role in detecting and pr...
Source: SafetyLit - September 19, 2023 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Antibiotics Destroy Memories?
Even in my earliest days of practicing medicine, I was never a big fan of prescribing antibiotics – except, of course, in cases of extreme or life-threatening infections. Because even back then, I was concerned about the damage these drugs could cause to your gut. That’s because trillions of microscopic bacteria – some that protect against certain diseases and some that can cause disease – live in your microbiome and exist in a delicate balance with each other. The problem is that antibiotics can’t distinguish between so-called “good” bacteria and the “bad” ones causing the infection. These drugs kill eve...
Source: Al Sears, MD Natural Remedies - September 19, 2023 Category: Complementary Medicine Authors: Jacob Tags: Anti-Aging Source Type: news

IVD Trends 2023-2028: Emerging Growth Markets in Asia, Latin America, and the Middle East
South Korea, Mexico, and Saudi Arabia are international markets that are essential to the present and future of in vitro diagnostics, finds Kalorama Information in the new report "The Worldwide Market for In Vitro Diagnostic Tests, 16th Edition" ARLINGTON, Va., Sept. 19, 2023...
Source: PRWeb: Medical Pharmaceuticals - September 19, 2023 Category: Pharmaceuticals Tags: SVY Source Type: news

Management of Mechanical Nasal Obstruction Isolated or Associated to Upper Airway Inflammatory Diseases in Real Life: Use of both Subjective and Objective Criteria
AbstractPurpose of ReviewMechanical nasal obstruction (MNO) is a prevalent condition with a high impact on patient ’s quality-of-life (QoL) and socio-economic burden. The aim of this study was to determine the usefulness of both subjective and objective criteria in the appropriate management of MNO, either alone or associated to upper airway inflammatory diseases such as allergic rhinitis (AR) or chronic rhino sinusitis with nasal polyps (CRSwNP).Recent FindingsA long debate persists about the usefulness of subjective and objective methods for making decisions on the management of patients with nasal obstruction. Establi...
Source: Current Allergy and Asthma Reports - September 19, 2023 Category: Allergy & Immunology Source Type: research

“Only Enough is Enough” campaign launched to expose hospital understaffing
Hospitals will be held accountable for unsafe staff levels under a new “Only Enough is Enough” campaign from UNISON launching this autumn, says the union today (Tuesday). As a result of having too few employees, many NHS trusts are unable to provide safe staffing levels, says UNISON. The union’s campaign aims to highlight hospitals that are failing to provide sufficient numbers of staff with the time they need to deliver quality patient care. The union wants trusts to work in partnership with NHS workers to solve their staffing problems. The campaign will initially have six pilot areas – Birmingham, Cam...
Source: UNISON Health care news - September 19, 2023 Category: UK Health Authors: Dan Ashley Tags: Article News Press release NHS staff safe staffing Source Type: news

‘ Only Enough is Enough ’ campaign launched to expose hospital understaffing
Hospitals will be held accountable for unsafe staff levels under a new ‘Only Enough is Enough’ campaign from UNISON launching this autumn, says the union today (Tuesday). As a result of having too few employees, many NHS trusts are unable to provide safe staffing levels, says UNISON. The union’s campaign aims to highlight hospitals that are failing to provide sufficient numbers of staff with the time they need to deliver quality patient care. The union wants trusts to work in partnership with NHS workers to solve their staffing problems. The campaign will initially have six pilot areas – Birming...
Source: UNISON meat hygiene - September 19, 2023 Category: Food Science Authors: Dan Ashley Tags: Article News Press release NHS staff safe staffing Source Type: news

One common virus is still killing thousands of children every year – but new vaccines offer hope | Devi Sridhar
Exciting scientific developments offer solutions to respiratory syncytial virus (RSV). The only barrier is costThe number one cause of infants being hospitalised in the US and Europe is a virus you ’ve probably never heard of:RSV. Most people experience it as a mild infection resembling a cold. But it can be very serious in babies and elderly people. The tell-tale symptoms are abnormally fast breathing, a caving-in of the chest between and under the ribs, and wheezing or crackles – worrying noises caused by the bronchial tubes being inflamed, or the small air sacs in the lungs filling with fluid. The virus makes it har...
Source: Guardian Unlimited Science - September 19, 2023 Category: Science Authors: Devi Sridhar Tags: Vaccines and immunisation Science Health Drugs Children Infant and child mortality Source Type: news

Identification of nonfunctional PABPC1L causing oocyte maturation abnormalities and early embryonic arrest in female primary infertility
In this study, we identified a homozygous missense mutation (c.536G>A, p.R179Q) and a compound heterozygous mutation (c.793C>T, p.R265W; c.1201C>T, p.Q401*) in PABPC1L in two unrelated infertile females characterized by recurrent oocyte maturation abnormalities and early embryonic arrest. These variants resulted in nonfunctional PABPC1L protein and were associated with impaired chromatin configuration and transcriptional silencing in GV oocytes. Moreover, the binding capacity of mutant PABPC1L to mRNAs related to oocyte maturation and early embryonic development was decreased significantly. Our findings revealed n...
Source: Clinical Genetics - September 19, 2023 Category: Genetics & Stem Cells Authors: Xiang Wang Ruixi Zhou Xiaowei Lu Siyu Dai Mohan Liu Chuan Jiang Yanting Yang Ying Shen Yan Wang Hanmin Liu Source Type: research

Student Perceptions of a New Course Using Argumentation in Medical Education
CONCLUSION: These findings support evidence from educational scholarship outside of medicine showing argumentation as a learning tool is well received by students. Further work is needed to determine whether it improves critical thinking skills and enhances learning in medical education.PMID:37724185 | PMC:PMC10505381 | DOI:10.2147/AMEP.S394219
Source: Adv Data - September 19, 2023 Category: Epidemiology Authors: Andrew J Foy Kent E Vrana Paul Haidet Bernice L Hausman Nancy E Adams Ira Ropson Daniel R Wolpaw David Rabago Richard B Mailman Xuemei Huang Source Type: research