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Total 478012 results found since Jan 2013.
Construction, evaluation, and AOP framework-based application of the EpPRS as a genetic surrogate for assessing environmental pollutants
CONCLUSIONS: EpPRSs can serve as a proxy for assessing pollutant internal exposure. The application of the EpPRS to disease risk assessment can reveal the toxic pathway and mode of action linking exposure and disease in detail, providing a basis for the development of environmental pollutant control strategies.PMID:37734146 | DOI:10.1016/j.envint.2023.108202
Source: Environment International - September 21, 2023 Category: Environmental Health Authors: Silu Chen Junyi Xin Zhutao Ding Lingyan Zhao Shuai Ben Rui Zheng Shuwei Li Huiqin Li Wei Shao Yifei Cheng Zhengdong Zhang Mulong Du Meilin Wang Source Type: research
Boron contamination and related health risk assessment in the soils collected from olive groves in İzmir province, Türkiye
In this study, it was aimed to determine the B pollution degree of the soils taken from the olive groves of İzmir province, which is approximately 180 km away from the B deposits in the Bigadiç district. In addition, the factors affecting boron adsorption and availability were discussed and the ecological and health risks of boron were evaluated. For this, soil samples were collected at depths of 0-30 cm from 118 olive groves and their B, Al, Fe, pH and organic matter contents were determined. The mean B content (47.08 mg/kg) of the study area was comparable to world-soil average B concentration (42 mg/kg). Also, B had a...
Source: Chemosphere - September 21, 2023 Category: Chemistry Authors: Memet Varol Ai şe Deliboran Halil Aytop Özgür Ateş Source Type: research
Benthic macroinvertebrate assemblages in relation to high ammonia loading: A 5-year fertilization experiment in 5 subtropical ponds
This study supported that ammonia toxicity to aquatic organisms was scale-dependent and should be evaluated at multiple scales.PMID:37734630 | DOI:10.1016/j.envpol.2023.122587
Source: Environmental Pollution - September 21, 2023 Category: Environmental Health Authors: Yan Li Yajing He Miao Liu Kazi Belal Uddin Yongjing Zhao Haijun Wang Yongde Cui Hongzhu Wang Source Type: research
Complications of epicutaneo-caval catheters: Pericardial effusion and cardiac tamponade in three preterm infants
This report presents, three cases of ECC-associated PCE/CT during NICU stay. All three patients were born before 30 weeks of gestation and weighed less than 1500 g. Echocardiography was used for diagnosis all patients. PCE/CT was detected incidentally in one patient and after hemodynamic deterioration in the other two. In one patient, CT was developed due to catheter malposition, and the other two patient, the catheter tip was found in the right atrium. PCE did not recur in any of the patients after pericardial fluid was drained and the catheters were removed. No PCE/CT-related deaths were observed. In all three patients, ...
Source: The Journal of Vascular Access - September 21, 2023 Category: Surgery Authors: Yasemin Ezgi K östekci Özlem Bayram Saniye Mertek Jeyhun Bakhtiyarzada Alperen Ayd ın Mehmet Mustafa Y ılmaz Beg üm Murt Ferhan Demirta ş Mehmet G ökhan Ramoğlu Emel Okulu Ömer Erdeve Tayfun U çar Beg üm Atasay Zeynep Eyileten Saadet Arsan Source Type: research
Essential Domains, Core Outcome Sets, and Measurements to Capture the Benefits and Harms of Implant Dentistry Interventions: The ID-COSM Initiative
Int J Periodontics Restorative Dent. 2023 Sep-Oct;43(5):537-539. doi: 10.11607/prd.2023.5.e.ABSTRACTConsensus on a valid and comprehensive set of outcomes to capture the full benefits and harms of implant dentistry interventions is key for progressing toward better clinical guidelines and policy. In this field, research remains fragmented and uses too many different outcomes. Studies are unable to cover the full breadth necessary to properly evaluate benefits, harms, and costs. Best-practice examples inspired the Implant Dentistry Core Outcome Set and Measurements (ID-COSM) initiative that identified four core outcome doma...
Source: International Journal of Periodontics and Restorative Dentistry - September 21, 2023 Category: Dentistry Authors: Maurizio S Tonetti Lisa Heitz-Mayfield Panos N Papapanou Mariano Sanz Source Type: research
Editorial: Essential Domains, Core Outcome Sets, and Measurements to Capture the Benefits and Harms of Implant Dentistry Interventions: The ID-COSM Initiative
Int J Periodontics Restorative Dent. 2023 Sep-Oct;43(5):537-539. doi: 10.11607/prd.2023.5.3.ABSTRACTConsensus on a valid and comprehensive set of outcomes to capture the full benefits and harms of implant dentistry interventions is key for progressing toward better clinical guidelines and policy. In this field, research remains fragmented and uses too many different outcomes. Studies are unable to cover the full breadth necessary to properly evaluate benefits, harms, and costs. Best-practice examples inspired the Implant Dentistry Core Outcome Set and Measurements (ID-COSM) initiative that identified four core outcome doma...
Source: International Journal of Periodontics and Restorative Dentistry - September 21, 2023 Category: Dentistry Source Type: research
Boron contamination and related health risk assessment in the soils collected from olive groves in İzmir province, Türkiye
In this study, it was aimed to determine the B pollution degree of the soils taken from the olive groves of İzmir province, which is approximately 180 km away from the B deposits in the Bigadiç district. In addition, the factors affecting boron adsorption and availability were discussed and the ecological and health risks of boron were evaluated. For this, soil samples were collected at depths of 0-30 cm from 118 olive groves and their B, Al, Fe, pH and organic matter contents were determined. The mean B content (47.08 mg/kg) of the study area was comparable to world-soil average B concentration (42 mg/kg). Also, B had a...
Source: Chemosphere - September 21, 2023 Category: Chemistry Authors: Memet Varol Ai şe Deliboran Halil Aytop Özgür Ateş Source Type: research
Phospholipid dependency of membrane protein insertion by the Sec translocon
Biochim Biophys Acta Biomembr. 2023 Sep 19:184232. doi: 10.1016/j.bbamem.2023.184232. Online ahead of print.ABSTRACTMembrane protein insertion into and translocation across the bacterial cytoplasmic membrane are essential processes facilitated by the Sec translocon. Membrane insertion occurs co-translationally whereby the ribosome nascent chain is targeted to the translocon via signal recognition particle and its receptor FtsY. The phospholipid dependence of membrane protein insertion has remained mostly unknown. Here we assessed in vitro the dependence of the SecA independent insertion of the mannitol permease MtlA into t...
Source: Biochimica et Biophysica Acta - September 21, 2023 Category: Biochemistry Authors: Max J den Uijl Arnold J M Driessen Source Type: research
NMR chemical shift prediction and structural elucidation of linker-containing oligo- and polysaccharides using the computer program CASPER
Carbohydr Res. 2023 Sep 4;533:108937. doi: 10.1016/j.carres.2023.108937. Online ahead of print.ABSTRACTCarbohydrate structures containing alkyl groups as aglycones are useful for investigating enzyme activity and glycan-protein interactions. Moreover, linker-containing oligosaccharides with a spacer group are commonly used to print glycan microarrays or to prepare protein-conjugates as vaccine candidates. The structural accuracy of these synthesized glycans are essential for interpretation of results from biological experiments in which the compounds have been used and NMR spectroscopy can unravel and confirm their structu...
Source: Carbohydrate Research - September 21, 2023 Category: Genetics & Stem Cells Authors: Kevin M Dorst G öran Widmalm Source Type: research
Carbon-Based Electron Buffer Layer on ZnOx-Fe5C2-Fe3O4 Boosts Ethanol Synthesis from CO2 Hydrogenation
Angew Chem Int Ed Engl. 2023 Sep 21:e202311786. doi: 10.1002/anie.202311786. Online ahead of print.ABSTRACTThe conversion of CO2 into ethanol with renewable H2 has attracted tremendous attention due to its integrated functions of carbon elimination and chemical synthesis, but still being challenging. The electronic property of catalyst is essential to determine the adsorption strength and configuration of the key intermediates, therefore altering the reaction network for targeted synthesis. Here, a carbon buffer layer is employed to tailor the electronic property of the ternary ZnOx-Fe5C2-Fe3O4, in which the electron trans...
Source: Angewandte Chemie - September 21, 2023 Category: Chemistry Authors: Yang Wang Wenhang Wang Ruosong He Meng Li Jinqiang Zhang Fengliang Cao Jianxin Liu Shiyuan Lin Xinhua Gao Guohui Yang Mingqing Wang Tao Xing Tao Liu Qiang Liu Han Hu Noritatsu Tsubaki Mingbo Wu Source Type: research
Caccinia macranthera Brand var. macranthera: Phytochemical analysis, phytotoxicity and antimicrobial investigations of essential oils with concomitant in silico molecular docking based on OPLS force-field
This study was conducted to extract the essential oils (EOs) of Caccinia macranthera identify their phytochemicals, evaluate their phytotoxicity, antimicrobial activity and enzyme inhibition effects using in silico molecular docking technique. EOs of aerial parts, seeds, and roots of C. macranthera were extracted and analyzed via Gas chromatography-Mass Spectrometry. The antibacterial activity of EOs were determined on nine microorganisms via disk diffusion and microbroth dilution assays. In addition, the allelopathic properties of EOs were investigated by calculating the IC50s for inhibition of germination, seedling lengt...
Source: Toxicon - September 21, 2023 Category: Toxicology Authors: Hadi Ghanbari Reza Ghanbari Abbas Delazar Samad Nejad Ebrahimi Mohammad Yousef Memar Sedigheh Bamdad Moghadam Sanaz Hamedeyazdan Hossein Nazemiyeh Source Type: research
Antivenom for sale? Availability and affordability of snakebite medicines across public and private health facilities in Rwanda
Toxicon. 2023 Sep 19:107292. doi: 10.1016/j.toxicon.2023.107292. Online ahead of print.ABSTRACTAntivenom is considered the safest and most effective treatment against snake envenomation (SBE); however, global shortages mean that many low-income countries struggle to meet demand. In Rwanda, chronic shortages of essential medicines are an important barrier to robust healthcare delivery and discourage snakebite victims from seeking hospital care. The aim of this retrospective, cross-sectional study was to evaluate the availability and affordability of commodities to treat SBE at hospitals and health centers. In total, our tea...
Source: Toxicon - September 21, 2023 Category: Toxicology Authors: Janna M Schurer Elijah Murara Janneke van Oirschot Gaby Ooms Source Type: research
Activism Is an Essential Nursing Role
Am J Nurs. 2023 Oct 1;123(10):52-58. doi: 10.1097/01.NAJ.0000979100.16233.cc.ABSTRACTNursing has a long history of activism, yet nurses are often heard to express their dislike of "politics" and their desire to stay away from the tense and contentious situations associated with political activism. Nurses, however, have a fundamental duty to advocate on behalf of their patients and communities. In this article, the authors discuss the rationale for and roots of political activism in nursing, the values that shape it, and the importance of nursing's stance on policies related to the health and well-being of those they serve....
Source: The American Journal of Nursing - September 21, 2023 Category: Nursing Authors: Peggy L Chinn Maureen Shawn Kennedy Source Type: research
Novel insight into the phenotype of microcephaly 19 in the patient with missense COPB2 mutation
This study describes a missense pathogenic homozygous variant (NM_004766.3:c.760 C > T, p.Arg254Cys) in the COPB2 gene, which was identified by Whole-Exome sequencing and confirmed by Sanger sequencing. The proband of the present study is an eight-and-a-half-year-old Iranian female who was born to consanguineous parents. She manifests global developmental delay, intellectual disability, microcephaly, seizures, spasticity, strabismus, and failure to thrive symptoms. Moreover, she is unable to stand, walk, or speak. Here we report the second homozygous mutation (NM_004766.3:c.760 C > T, p.Arg254Cys) in the COPB2 gene i...
Source: European Journal of Medical Genetics - September 21, 2023 Category: Genetics & Stem Cells Authors: Amirmasoud Shiri Hossein Jafari Khamirani Neda Kamal Jamal Manoochehri Mehdi Dianatpour Seyed Mohammad Bagher Tabei Seyed Alireza Dastgheib Source Type: research
Nutrition-associated health levels in persons with cancer: item response modelling based on the International Classification of Functioning, Disability and Health
CONCLUSIONS: The study constructed an evidence-based ICF scale for nutrition conditions in patients with cancer with 32-item and 2PLM for evaluating nutrition-associated health level in persons with cancer, including high validity and reliability.CLINICAL REHABILITATION IMPACT: The IRT model based on ICF provided a promising assessment tool to discriminate nutrition-associated health level of persons with cancer, and offered an auxiliary method for selecting rehabilitation intervention targets. This has the potential to lead to improved outcomes in cancer treatment and increased quality of life for cancer survivors.PMID:37...
Source: European Journal of Physical and Rehabilitation Medicine - September 21, 2023 Category: Rehabilitation Authors: Jin-Jin Chen Zi-Yan Zhu Jia-Jia Bian Feng Lin Source Type: research
