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Total 478012 results found since Jan 2013.
In-vitro antibacterial activity and mechanism of Monarda didyma essential oils against Carbapenem-resistant Klebsiella pneumoniae
To fight the global epidemic of drug-resistant bacteria, essential oils have gained increasing attention as a new source of antibiotics. The antimicrobial activity of Monarda didyma essential oils (MDEO) for the
Source: BMC Microbiology - September 20, 2023 Category: Microbiology Authors: Ying Chen, Jinda Zhao, Chenyu Liu, Dongmei Wu and Xianhe Wang Tags: Research Source Type: research
CTCF is essential for proper mitotic spindle structure and anaphase segregation
AbstractMitosis is an essential process in which the duplicated genome is segregated equally into two daughter cells. CTCF has been reported to be present in mitosis and has a role in localizing CENP-E, but its importance for mitotic fidelity remains to be determined. To evaluate the importance of CTCF in mitosis, we tracked mitotic behaviors in wild-type and two different CTCF CRISPR-based genetic knockdowns. We find that knockdown of CTCF results in prolonged mitoses and failed anaphase segregation via time-lapse imaging of SiR-DNA. CTCF knockdown did not alter cell cycling or the mitotic checkpoint, which was activated ...
Source: Chromosoma - September 20, 2023 Category: Genetics & Stem Cells Source Type: research
A high-throughput big-data orchestration and processing system for the High Energy Photon Source
High-data-throughput and multimodal-acquisition experiments will prevail in next-generation synchrotron beamlines. Orchestrating dataflow pipelines connecting the data acquisition, processing, visualization and storage ends are becoming increasingly complex and essential for enhancing beamline performance. Mamba Data Worker (MDW) has been developed to address the data challenges for the forthcoming High Energy Photon Source (HEPS). It is an important component of the Mamba experimental control and data acquisition software ecosystem, which enables fast data acquisition and transmission, dynamic configuration of data proces...
Source: Journal of Synchrotron Radiation - September 20, 2023 Category: Physics Authors: Li, X. Zhang, Y. Liu, Y. Li, P. Hu, H. Wang, L. He, P. Dong, Y. Zhang, C. Tags: beamline software data acquisition data management high-throughput experiment multimodal experiments research papers Source Type: research
Online dynamic flat-field correction for MHz microscopy data at European XFEL
The high pulse intensity and repetition rate of the European X-ray Free-Electron Laser (EuXFEL) provide superior temporal resolution compared with other X-ray sources. In combination with MHz X-ray microscopy techniques, it offers a unique opportunity to achieve superior contrast and spatial resolution in applications demanding high temporal resolution. In both live visualization and offline data analysis for microscopy experiments, baseline normalization is essential for further processing steps such as phase retrieval and modal decomposition. In addition, access to normalized projections during data acquisition can play ...
Source: Journal of Synchrotron Radiation - September 20, 2023 Category: Physics Authors: Birnsteinova, S. Ferreira de Lima, D.E. Sobolev, E. Kirkwood, H.J. Bellucci, V. Bean, R.J. Kim, C. Koliyadu, J.C.P. Sato, T. Dall'Antonia, F. Asimakopoulou, E.M. Yao, Z. Buakor, K. Zhang, Y. Meents, A. Chapman, H.N. Mancuso, A.P. Villanueva-Perez, P. Vago Tags: MHz X-ray microscopy flat-field correction online data processing X-ray free-electron laser research papers Source Type: research
Genome-wide identification, phylogenetic and expression pattern analysis of HSF family genes in the Rye (Secale cereale L.)
Heat shock factor (HSF), a typical class of transcription factors in plants, has played an essential role in plant growth and developmental stages, signal transduction, and response to biotic and abiotic stres...
Source: BMC Plant Biology - September 20, 2023 Category: Biology Authors: Yanyan Ren, Rui Ma, Muhua Xie, Yue Fan, Liang Feng, Long Chen, Hao Yang, Xiaobao Wei, Xintong Wang, Kouhan Liu, Peng Cheng and Baotong Wang Tags: Research Source Type: research
Obstetric referrals, complications and health outcomes in maternity wards of large hospitals during the COVID-19 pandemic: a mixed methods study of six hospitals in Guinea, Nigeria, Uganda and Tanzania
Conclusions
Maternal and perinatal survival was negatively affected in referral hospitals in sub-Saharan Africa during COVID-19. Routine data systems in referral hospitals must be fully used as they hold potential in informing adaptations of maternal care services. If combined with information on women’s and care providers’ needs, this can contribute to ensuring continuation of essential care provision during emergency.
Source: BMJ Open - September 20, 2023 Category: General Medicine Authors: Benova, L., Semaan, A., Afolabi, B. B., Amongin, D., Babah, O. A., Dioubate, N., Harissatou, N., Kikula, A. I., Nakubulwa, S., Ogein, O., Adroma, M., Anzo Adiga, W., Diallo, A., Diallo, I. S., Diallo, L., Cellou Diallo, M., Maomou, C., Mtinangi, N., Sy, T Tags: Open access, Health services research, COVID-19 Source Type: research
Evaluation of different debridement strategies for implant-abutment connections: An in vitro study
Technical complications, including abutment fracture, are a clinical reality. After retrieving failed components, re-establishing a reliable implant-abutment connection is essential, but recommendations on how to clean the interface are lacking.
Source: Journal of Prosthetic Dentistry - September 20, 2023 Category: Dentistry Authors: Lilly K. Lang, Matthias Karl, Virgilia Kl är Tags: Research and Education Source Type: research
Achieving optimal implant esthetics using a team approach Part 1 a review of evidence-based criteria in implant treatment
As dental implants have evolved into a universally accepted treatment option, it is essential to identify nuances of the peri-implant complex and their impact on treatment given the increasing evidence of peri-implantitis and implant loss. A thorough knowledge of anatomy and biology, careful treatment planning, correct placement, prosthetic and occlusal design, and proper long-term maintenance all play a role in dental implant therapy. The goal of this part 1 presentation is to review evidence-based criteria in implant treatment including the surgical and restorative parameters, and the desired implant features, with the o...
Source: Journal of Prosthetic Dentistry - September 20, 2023 Category: Dentistry Authors: Graziano D. Giglio, Ana Becil Giglio Tags: JPD Digital Source Type: research
Peroxiredoxins in erythrocytes: far beyond the antioxidant role
AbstractThe red blood cells (RBCs) are essential to transport oxygen (O2) and nutrients throughout the human body. Changes in the structure or functioning of the erythrocytes can lead to several deficiencies, such as hemolytic anemias, in which an increase in reactive oxidative species generation is involved in the pathophysiological process, playing a significant role in the severity of several clinical manifestations. There are important lines of defense against the damage caused by oxidizing molecules. Among the antioxidant molecules, the enzyme peroxiredoxin (Prx) has the higher decomposition power of hydrogen peroxide...
Source: Journal of Molecular Medicine - September 20, 2023 Category: Molecular Biology Source Type: research
Interrelationship between dental clinicians and laboratory technicians: a qualitative study
Effective communication among members of the dental team is essential for the delivery of high-quality dental care. However, an in-depth understanding of issues concerning the interrelationship between dental ...
Source: BMC Oral Health - September 20, 2023 Category: Dentistry Authors: Eman H. Ismail and Dalya Al-Moghrabi Tags: Research Source Type: research
Synthesis of Superarmed Thioglycosides via the Ring Opening of 1,2-Orthoesters
Synlett DOI: 10.1055/a-2132-1938 Since the advent of the armed–disarmed strategy, thioglycosides have become essential tools in one-pot oligosaccharide synthesis. The continuum of glycosyl donor reactivity has since been expanded to include so-called ‘superarmed’ thioglycoside donors whose reactivity relies on more than just the inductive effects of protecting groups. Here we report a new method for the synthesis of superarmed thioglycosides via the ring opening of 1,2-orthoesters. This method ensures the necessary 1,2-trans stereochemistry, and importantly, makes use of trimethylsilyl thioethers as sulfur nucleophil...
Source: Synlett - September 20, 2023 Category: Chemistry Authors: Beato, Zoe Zhu, Xiangming Tags: letter Source Type: research
Interpretation of the Intracranial Electroencephalogram of the Human Hippocampus
Understanding and discriminating the normal and abnormal elements of the intracranial electroencephalogram (iEEG) is essential in decision-making for epilepsy surgery. The hippocampus is widely acknowledged as a key structure in decision-making processes for surgical treatment in temporal lobe epilepsy and epilepsies that involve the mesial temporal structures. This review will provide a summary of the current state of our knowledge and understanding regarding normal and abnormal features of the iEEG of the human hippocampus.
Source: Neurosurgery Clinics of North America - September 20, 2023 Category: Neurosurgery Authors: Vasileios Kokkinos Source Type: research
Behavior Changes Associated with Metabolic Disease of Dogs and Cats
Like many physical disorders, the clinical signs associated with metabolic diseases affecting thyroid, adrenal, and pancreatic function are reflective of nonspecific changes in behavior. Additionally, patients who have underlying disorders associated with fear, anxiety, stress, conflict, and/or panic may be under treatment with medications that alter basal thyroid, glucose, and cortisol levels. Through reinforcement and punishment of behaviors associated with clinical signs caused by organic or iatrogenic endocrine disease, behaviors can be perpetuated and become persistent patterns. Screening all patients presenting with ...
Source: Veterinary Clinics of North America: Small Animal Practice - September 20, 2023 Category: Veterinary Research Authors: Lisa Radosta Source Type: research
Disruption of the inositol phosphorylceramide synthase gene affects < i > Trypanosoma cruzi < /i > differentiation and infection capacity
by Nailma S. Aprigio-Santos, Carlos F. Estevez-Castro, Juan P. Macedo, Daniela F. Chame, Thiago Castro-Gomes, Mariana Santos-Cardoso, Gabriela A. Burle-Caldas, Courtney N. Covington, Patrick G. Steel, Terry K. Smith, Paul W. Denny, Santuza M. R. Teixeira
Sphingolipids (SLs) are essential components of all eukaryotic cellular membranes. In fungi, plants and many protozoa, the primary SL is inositol-phosphorylceramide (IPC).Trypanosoma cruzi is a protozoan parasite that causes Chagas disease (CD), a chronic illness for which no vaccines or effective treatments are available. IPC synthase (IPCS) has been considered an ideal ...
Source: PLoS Neglected Tropical Diseases - September 20, 2023 Category: Tropical Medicine Authors: Nailma S. Aprigio-Santos Source Type: research
Trial By Error: A Physiotherapist ’ s Guide to Understanding and Managing ME/CFS
By David Tuller, DrPH A new book, A Physiotherapist’s Guide to Understanding and Managing ME/CFS, has arrived at a timely moment. With so many long Covid patients being diagnosed with ME or ME/CFS, it is essential that physiotherapists—or physical therapists, in the US—grasp the essentials of the disease, and in particular the existence of post-exertional … Trial By Error: A Physiotherapist’s Guide to Understanding and Managing ME/CFS Read More »
Source: virology blog - September 19, 2023 Category: Virology Authors: David Tuller Tags: Uncategorized book physical therapy physios for ME physiotherapy Source Type: blogs
